Promoting versatile vaccine development for emerging pandemicsPerspective Published on 2021-02-112022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] accelerate approach COVID-19 pandemic demonstrated Diseases flexible medical countermeasure Medical research pandemic Pandemics pathogen pathogen-specific Pathogens platform Preclinical research promote Promoting Research SARS-CoV-2 vaccine translate Vaccine Vaccine development vaccine platform Vaccines [DOI] 10.1038/s41541-021-00290-y PMC 바로가기 [Article Type] Perspective
On Drug-Membrane Permeability of Antivirals for SARS-CoV-2SARS-CoV-2에 대한 항바이러스제의 약물-막 투과성Article Published on 2021-02-112022-09-11 Journal: The journal of physical chemistry letters [Category] 치료제, [키워드] approach Behavior Bioavailability cellular organelles Characteristics Combination composed Compound contribute coronavirus determine drug drug design drugs effective drug effective drugs Efficacy endoplasmic reticulum membranes FIVE flexible Golgi highlight identify Interaction mammalian membrane membrane permeability membranes mitochondrial molecular dynamics Molecular dynamics simulation molecules negative correlation parameter permeability permeation plasma predict Proteins required SARS-CoV-2 Spike protein statistical analysis targets transmembrane variety Viral viral envelope [DOI] 10.1021/acs.jpclett.0c02397 PMC 바로가기 [Article Type] Article
Expressive Flexibility and Dispositional Optimism Contribute to the Elderly’s Resilience and Health-Related Quality of Life during the COVID-19 PandemicArticle Published on 2021-02-102022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] affecting age association baseline clinical psychology contribute COVID-19 COVID-19 outbreak dispositional optimism elderly emotional expression expressive expressive flexibility Factors Final flexibility flexible Follow-up help life Linear regression Mental mental component summary optimism Outpatient Perspective physical physical component summary physician promote Psychological Psychological factor psychologist public health Quality Quality of life recognize recruited Resilience subjects [DOI] 10.3390/ijerph18041698 PMC 바로가기 [Article Type] Article
CoronaHiT: high-throughput sequencing of SARS-CoV-2 genomesCoronaHiT: SARS-CoV-2 게놈의 높은 처리량 시퀀싱Method Published on 2021-02-092022-08-13 Journal: Genome Medicine [Category] MERS, 유전자 메커니즘, [키워드] ARTIC Clustering demonstrated flexible Genetic Genome genome coverage Illumina Illumina platforms likelihood MinION Multiplexing Nanopore NGS pandemic PCR products platform protocol rapid expansion SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequencing SARS-CoV-2 genomes sequenced Sequencing supplementary material transposase was obtained [DOI] 10.1186/s13073-021-00839-5 PMC 바로가기 [Article Type] Method
Curved-crease origami face shields for infection controlResearch Article Published on 2021-02-082022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] COVID-19 pandemic distribution face Face shield flat flexible fluids infection control methodology Personal protective equipment PPE produced shown Variation variety Volume [DOI] 10.1371/journal.pone.0245737 PMC 바로가기 [Article Type] Research Article
Remote data collection during COVID-19 restrictions: an example from a refugee and asylum-seeker participant group in the UKLetter Published on 2021-02-052022-10-29 Journal: Trials [Category] Coronavirus, MERS, [키워드] approach Arabic Asylum Asylum seeker benefit COVID-19 described digital divide Emergency evaluate example flexible Implementing implication indicated Intervention lockdown management novel refugee Registration remote Remote Data Collection researcher resulting risk Risk management self social distancing Stress Trial [DOI] 10.1186/s13063-021-05058-2 PMC 바로가기 [Article Type] Letter
In silico Exploration of Inhibitors for SARS-CoV-2’s Papain-Like ProteaseChemistry Published on 2021-02-042022-10-31 Journal: Frontiers in Chemistry [Category] COVID-19, [키워드] acute respiratory syndrome binding carried caused complex coronavirus Coronavirus disease 2019 COVID-19 docking exploration FDA-approved drug flexible global pandemic help in silico inhibiting inhibitor inhibitors investigated maturation MD simulation Molecular dynamics simulation molecular dynamics simulation (MD) molecular mechanism MPro Papain-like protease PLPro protease SARS-CoV-2 target Treatment [DOI] 10.3389/fchem.2020.624163 PMC 바로가기 [Article Type] Chemistry
Clinical trials in a COVID-19 pandemic: Shared infrastructure for continuous learning in a rapidly changing landscapeCOVID-19 전염병의 임상 시험: 빠르게 변화하는 환경에서 지속적인 학습을 위한 공유 인프라Articles Published on 2021-02-032022-09-11 Journal: Clinical Trials (London, England) [Category] MERS, SARS, 임상, [키워드] adaptive Analysis ARMS balancing benefit center clinical clinical trial clinical trials conducted coordinating core protocol COVID-19 COVID-19 crisis creating Data & Safety Monitoring Board Data collection Data Coordinating Center disease Effective vaccines Efficiency efficient infrastructure element elements Endpoint endpoints evaluate facilitate feature flexible include Infrastructure Intervention involved Master protocol Outpatient pandemic Patient platform Platform protocol Pragmatic protocol provide registry researchers resource respond rigor robust Safety Monitoring Board strength Therapies time-consuming translational Treatment Trial trials utility while [DOI] 10.1177/1740774520988298 PMC 바로가기 [Article Type] Articles
Access to data from clinical trials in the COVID-19 crisis: open, flexible, and time-sensitiveCOVID-19 위기의 임상 시험 데이터에 대한 액세스: 개방적이고 유연하며 시간에 민감합니다.Article Published on 2021-02-012022-09-11 Journal: Journal of clinical epidemiology [Category] 임상, [키워드] access clinical trial COVID-19 flexible [DOI] 10.1016/j.jclinepi.2020.10.008 PMC 바로가기 [Article Type] Article
Flexible care in breast cancer유방암의 유연한 치료Review Published on 2021-02-012022-09-12 Journal: ESMO open [Category] MERS, 진단, [키워드] Administered administration at-home care Breast cancer can be used Cancer cancer treatment Care clinical clinics COVID-19 COVID-19 pandemic element Europe expand feasible flexible hcp Healthcare professional hospital hospitals intravenous Local Numerous offer oncology outpatient clinic Patient patient selection patients Patients with cancer pilot study primary care Quality of life reduce reducing remote cancer care subcutaneous administration the patient trastuzumab. Travel Treatment Trial [DOI] 10.1016/j.esmoop.2020.100007 PMC 바로가기 [Article Type] Review