Serological response to a third booster dose of BNT162b2 COVID-19 vaccine among seronegative cancer patients혈청 음성 암 환자에서 BNT162b2 COVID-19 백신의 3차 추가 접종에 대한 혈청학적 반응Article Published on 2022-08-012022-09-11 Journal: Cancer Reports [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Administered antibody Antibody Response anticancer BNT162b2 booster booster dose Cancer cancer patient COVID-19 COVID-19 vaccine detect domain dose elicit ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated IgG IgG titers Immunoglobulin Immunoglobulin G of BNT162b2 Patient Patients with cancer Pfizer/BioNTech pilot study Receptor-binding domain Sample SARS-CoV-2 second vaccination serological response seronegative seropositive small sample size student t-test the RBD two-sided vaccine dose vaccine doses [DOI] 10.1002/cnr2.1645 PMC 바로가기 [Article Type] Article
Difference in safety and humoral response to mRNA SARS-CoV-2 vaccines in patients with autoimmune neurological disorders: the ANCOVAX study자가면역 신경계 장애 환자에서 mRNA SARS-CoV-2 백신에 대한 안전성 및 체액 반응의 차이: ANCOVAX 연구Article Published on 2022-08-012022-09-11 Journal: Journal of Neurology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 95% CI ANC anti-CD20 anti-SARS-CoV-2 anti-SARS-CoV-2 IgG Anti-spike antibody antibody levels Antibody Response Assessing Autoimmune Autoimmune neurological disorders BNT162b2 BNT162b2 vaccine Clinical practice condition Control difference dose Effect evaluated fingolimod humoral Humoral response IgG immune therapy immunotherapies Immunotherapy incidence increased risk IQR Local longitudinal study mAb median age mRNA mRNA vaccine mRNA vaccines mRNA-1273 mRNA-1273 vaccine Multiple multiple sclerosis neurological Neurological status not different of BNT162b2 Patient patients rate ratio Receptor binding domain reduced Relapse Safe SARS-CoV-2 SARS-CoV-2 vaccine Sars-Cov2-mRNA vaccine. second dose seroconversion rate side Side effects systemic reaction systemic reactions the antibody response Treatment vaccination Vaccine were assessed [DOI] 10.1007/s00415-022-11142-7 PMC 바로가기 [Article Type] Article
Comparative Profiles of SARS-CoV-2 Spike-Specific Human Milk Antibodies Elicited by mRNA- and Adenovirus-Based COVID-19 VaccinesArticle Published on 2022-08-012023-07-09 Journal: Breastfeeding medicine : the official journal of t [Category] COVID19(2023년), [키워드] COVID-19 IgG milk antibodies SARS-CoV-2 Secretory antibody Vaccines [DOI] 10.1089/bfm.2022.0019
Robust humoral and cellular immune responses in long-term convalescent COVID-19 individuals following one-dose SARS-CoV-2 inactivated vaccinationSARS-CoV-2 비활성화 백신 접종 후 장기간 회복 중인 COVID-19 개인의 강력한 체액 및 세포 면역 반응Article Published on 2022-08-012022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] addition anti-S Antigen antigen-specific T cell Antigen-specific T cells B cell booster caused CD4 Cellular immune response characterized convalescent COVID-19 death demonstrated Efficacy exhibited frequencies Frequency healthy healthy individual healthy individuals Hospitalization humoral IFN-γ IgG IL-2 immune immune responses inactivated Inactivated vaccine individual infected patient Infection long-term convalescent. NAbs Neutralizing antibodies neutralizing antibody neutralizing capacity RBD IgG RBD-specific IgG recipients recovered patient recovered patients robust SARS-CoV-2 SARS-CoV-2 inactivated vaccine SARS-CoV-2 RBD SARS-CoV-2 vaccine severe disease significantly significantly higher significantly increased single dose subject T cell T cell response T cell responses T cells the vaccine TNF-α utility vaccination Vaccine vaccine-induced immune response variants variants of concern VoC VOCs wild type [DOI] 10.3389/fimmu.2022.966098 PMC 바로가기 [Article Type] Article
Blood and saliva SARS-CoV-2 antibody levels in self-collected dried spot samples자가 수집 건조 반점 샘플의 혈액 및 타액 SARS-CoV-2 항체 수준Article Published on 2022-08-012022-09-12 Journal: Medical Microbiology and Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] analyses analyzed antibody Blood COVID-19 COVID-19 infection Dried spot sample examined exposure healthcare healthy IgA IgG IgM immune response Infection infections MONITOR Non-invasive participant percentage proportion questionnaire Questionnaires reported Saliva SARS-CoV-2 SARS-CoV-2 antibody sensitivity specificity vaccination Vaccinations while [DOI] 10.1007/s00430-022-00740-x PMC 바로가기 [Article Type] Article
Heterogeneity in IgG-CD16 signaling in infectious disease outcomesArticle Published on 2022-08-012022-11-15 Journal: Immunological reviews [Category] 진단, [키워드] acute infections allele binding contribute coronavirus disease COVID-19 dengue disease disease downstream driven by effector functions. expression Fc afucosylation form functions glycosylation heterogeneity IgG IgG antibody IgG1 IgG1 antibodies immune complex Immune homeostasis Infection Infectious disease Inflammation Inflammatory response inflammatory signaling ligands mechanism modulate outcome Pathogenesis pathogenic required Signaling viral infection while [DOI] 10.1111/imr.13109 PMC 바로가기
Vaccine based on folded receptor binding domain-PreS fusion protein with potential to induce sterilizing immunity to SARS-CoV-2 variantsSARS-CoV-2 변이체에 대한 살균 면역을 유도할 수 있는 접힌 수용체 결합 도메인-PreS 융합 단백질 기반 백신Article Published on 2022-08-012022-09-11 Journal: Allergy [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antibody Antibody Response Antigen C-terminus carrier cellular combination vaccine construction convalescent coronavirus COVID-19 COVID-19 pandemic fused fusion protein Genetic genotypes HBV healthy subject healthy subjects hepatitis B Hepatitis B virus human cell human cells IgG IgG antibodies IgG antibody IgG response Immunity immunized in vitro in vivo induce inhibited Interaction maintenance median mucosal secretions Neutralizing Neutralizing antibodies neutralizing antibody neutralizing titers Omicron variant pandemic Protein random Random sample RBD RBD-specific IgG RBD-specific IgG response receptor ACE2 Receptor binding Receptor-binding domain recombinant fusion protein Registered replicate respiratory response responsible robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specific antibodies specific IgG antibodies spike Spike protein sterilizing immunity subject subjects subunit Subunit vaccine surface antigen sustained Vaccine Viral viral replication virus entry virus-neutralizing VNT [DOI] 10.1111/all.15305 PMC 바로가기 [Article Type] Article
Cellular and humoral immune response to SARS-CoV-2 vaccination and booster dose in immunosuppressed patients: An observational cohort study면역억제 환자에서 SARS-CoV-2 예방접종 및 추가 용량에 대한 세포 및 체액 면역 반응: 관찰 코호트 연구Observational Study Published on 2022-08-012022-09-12 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Ad26.COV2.S anti-CD20 anti-SARS-CoV-2 S1 IgG B cell BNT162b2 booster booster dose booster vaccination Cellular immune response cellular immunity cellular response clinical COVID-19 defined ELISA Factor Healthcare system humoral humoral immune response IgG IGRA Immunosuppressed immunosuppressed patient Immunosuppression individual interferon gamma lymphoma median age monoclonal antibody mRNA-1273 Observational cohort study Patient patient groups performed populations positive receptor retrospective SARS-CoV-2 SARS-CoV-2 vaccination serology significantly higher sphingosine vaccination vaccine response variable were measured [DOI] 10.1016/j.jcv.2022.105217 PMC 바로가기 [Article Type] Observational Study
Efficacy and safety of mRNA SARS-CoV-2 vaccines in lung transplant recipients폐 이식 환자에서 mRNA SARS-CoV-2 백신의 효능 및 안전성Article Published on 2022-08-012022-09-12 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] adverse event analyzed Antibody Response BNT162b2 vaccine clinical study conducted Control controls COVID-19 dose Efficacy and safety evaluated Fever humoral immune response IgG Immunosuppression IMPROVE in both groups increase in Japan Logistic regression lung transplant lung transplantation mRNA mRNA vaccination mRNA vaccine mRNA-1273 vaccine nonrandomized Open-label percentage plasma concentration positive antibody response Prospective Study recipient recruited regimen SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 vaccination SARS-CoV-2 vaccine serology significantly the antibody response the vaccine university vaccination Vaccine Vaccines was measured while [DOI] 10.1016/j.jiac.2022.04.019 PMC 바로가기 [Article Type] Article
Impaired humoral and cellular response to primary COVID-19 vaccination in patients less than 2 years after allogeneic bone marrow transplant동종 골수 이식 후 2년 미만의 환자에서 1차 COVID-19 예방 접종에 대한 체액 및 세포 반응 손상Article Published on 2022-08-012022-09-11 Journal: British Journal of Haematology [Category] MERS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adverse outcome adverse outcomes Allogeneic allogeneic bone marrow transplant analysed anti-S IgG Anti-spike BNT162b2 Bone marrow booster Cell Cell-mediated immunity cellular response ChAdOx1 Cohort coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) Coronavirus-2 COVID-19 COVID-19 vaccination Critical defined enzyme-linked immunospot Evidence evidence of haematopoietic stem cell transplant (HSCT) HCs healthy control high risk HSCT HSCT recipient HSCT recipients humoral IFNγ IgG Immunoglobulin Immunoglobulin G ImmunoSpot Impaired interferon less majority Patient Prophylactic prophylactic measure prophylactic measures rate of seroconversion recipient respiratory responders Seroconversion Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) significantly higher significantly lower stem cell T-cell T-cell Response T-cell responses These data titre Transplant vaccination schedule Vaccination strategy Vaccine vaccine immunogenicity Vaccines variants [DOI] 10.1111/bjh.18312 PMC 바로가기 [Article Type] Article