Comparison of three serological chemiluminescence immunoassays for SARS-CoV-2, and clinical significance of antibody index with disease severitySARS-COV-2에 대한 3 개의 혈청 발광 면역 분석 및 질병 중증도에 대한 항체 지수의 임상 적 중요성의 비교Comparative Study Published on 2021-06-292022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 바이오마커, 진단, 치료법, [키워드] (Abbott Abbott access acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody automated Beckman Coulter chemiluminescence immunoassay clinical implication clinical implications clinical marker clinical markers Clinical severity Clinical significance collected coronavirus correlation correlation coefficient COVID-19 disease disease severity IgG IgG antibody IgM immunoassay Infection investigated Molecular tests nucleocapsid nucleocapsids Patient patients with COVID-19 Quantitative respiratory Result SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 IgG antibody SARS-CoV2 serological severe acute respiratory syndrome Coronavirus severe disease Siemens significantly significantly higher specimen spikes statistically the SARS-CoV-2 Total was measured [DOI] 10.1371/journal.pone.0253889 PMC 바로가기 [Article Type] Comparative Study
iCAT: diagnostic assessment tool of immunological history using high-throughput T-cell receptor sequencingiCAT: 고처리량 T 세포 수용체 시퀀싱을 사용한 면역학적 병력의 진단 평가 도구Software Tool Article Published on 2021-06-292022-09-12 Journal: F1000Research [Category] MERS, 진단, [키워드] absence Accuracy Biomarker Biomarkers can be used Classifier Cohort COVID-19 diagnose diagnosed diagnostic diagnostic classification DNA sequence Genetic high accuracy identify immune immunological independent Infection mice naïve pathogen pathogen-specific positive provide R software package R-package recorded SARS-CoV-2 sequence Sequencing statistically T-cell T-cell receptor T-cell receptor sequencing T-cell Response TCR loci TCR sequence TCR sequencing TCRs unique virus [DOI] 10.12688/f1000research.27214.2 PMC 바로가기 [Article Type] Software Tool Article
Comparing the impact on COVID ‐19 mortality of self‐imposed behavior change and of government regulations across 13 countriesResearch Article Published on 2021-06-282022-10-31 Journal: Health Services Research [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval adopted approaches arising change consequence coronavirus disease country COVID COVID‐19 death death rates decrease dimension disease Effect Efficacy European events Face mask fatality finding Google mobility data Government Impact impacts implication Intervention lockdown magnitude Mortality nonpharmaceutical intervention Nonpharmaceutical interventions NPI NPIs objective Other pandemic per day Primary outcome principal reduce reduced reducing regression analysis Regulation salience same order SARS‐CoV‐2 School secondary Source statistically subsequent Transmission Travel used to evaluate Variation voluntary behavior change Western Europe [DOI] 10.1111/1475-6773.13688 PMC 바로가기 [Article Type] Research Article
Evaluation of systemic involvement of Coronavirus disease 2019 through spleen; size and texture analysis비장을 통한 코로나바이러스 질병 2019의 전신적 관여 평가; 크기 및 질감 분석Article Published on 2021-06-282022-09-12 Journal: Turkish Journal of Medical Sciences [Category] MERS, SARS, 진단, [키워드] age Analysis change changes in co-occurrence Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 decrease demonstrated deviation diagnosed early stage evaluated feature Features females Follow-up follow-up time France heterogeneity Hounsfield unit interquartile range lung involvement males material no statistically significant difference noninvasive organs p-values parenchymal Patient Result spleen spleen size Standard deviation statistically statistically significant statistically significant difference Texture analysis Thoracic variance was performed [DOI] 10.3906/sag-2009-270 PMC 바로가기 [Article Type] Article
Evaluation of the chest computed tomography and hemogram data in patients with COVID-19: the importance of thymusCOVID-19 환자의 흉부 컴퓨터 단층 촬영 및 혈색소 측정 데이터 평가: 흉선의 중요성Article Published on 2021-06-282022-09-12 Journal: Turkish Journal of Medical Sciences [Category] MERS, 진단, [키워드] age blood cell calculated Chest Chest computed tomography Computed tomography COVID-19 COVID-19 patient COVID-19 patients evaluated fat imaging increase in involution laboratory data lung lung involvement lymphocyte Lymphocyte count material neutrophil NLR observer Patient patients patients with COVID-19 Peripheral blood peripheral blood cell Platelet platelet counts Pneumonia positive Radiologists Result RT-PCR testing scored severity significantly significantly lower statistical significance statistically thymus tissue tomography Viral pneumonia was determined were recorded [DOI] 10.3906/sag-2007-306 PMC 바로가기 [Article Type] Article
COVIDOUTCOME—estimating COVID severity based on mutation signatures in the SARS-CoV-2 genomeCOVIDOUTCOME - SARS-CoV-2 게놈의 돌연변이 시그니처를 기반으로 COVID 심각도 추정Original Article Published on 2021-06-262022-09-11 Journal: Database: The Journal of Biological Databases and [Category] SARS, 변종, [키워드] Accuracy adjusted age Algorithm an area Analysis approach association AUC automated best Bia confidence interval COVID COVID-19 cross disease severity Efficiency Final Follow-up Genome input multiple testing Mutation Numerous outcome platform Protein provide Random forest random forest classification Real-time analysis Region repeated SARS-CoV-2 sequence severe disease severity significantly statistical statistically stratified the SARS-CoV-2 genome training set untranslated region UTR Viral viral genome viral genomes were used [DOI] 10.1093/database/baab020 PMC 바로가기 [Article Type] Original Article
Association between Hyperglycemia at Hospital Presentation and Hospital Outcomes in COVID-19 Patients with and without Type 2 Diabetes: A Retrospective Cohort Study of Hospitalized Inner-City COVID-19 PatientsArticle Published on 2021-06-262022-10-30 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] Acute kidney injury Admission age blood glucose Boston center confounder confounders coronavirus COVID-19 COVID-19 patient database defined demographic determine diabete female higher risk hospital Hospitalized hyperglycemia ICU admission in-hospital mortality rate Inflammatory intubation Mortality occurred outcome Patient presentation SARS-CoV-2 severe COVID-19 Shock significantly statistically subset T2D Type type 2 diabete Type 2 diabetes mellitus university were excluded [DOI] 10.3390/nu13072199 PMC 바로가기 [Article Type] Article
Bell’s Palsy After 24 Hours of mRNA-1273 SARS-CoV-2 VaccineEmergency Medicine Published on 2021-06-262022-10-31 Journal: Cureus [Category] COVID-19, [키워드] administration Bell’s palsy bell’s palsy Brain Case report Coronavirus disease 2019 COVID-19 Diagnosis discharged home Emergency use authorization Facial nerve FDA Follow-up healthy hour incidence interferon interferons MRI mRNA COVID-19 vaccine mRNA vaccine mRNA vaccines mRNA-1273 mRNA-1273 vaccine offered palsy pandemic Patient Population potential mechanism randomized trial receiving risk factor SARS-CoV-2 second dose Side effect statistically stroke Surveillance Symptom the placebo group the vaccine Type Vaccine Vaccines weakness [DOI] 10.7759/cureus.15935 PMC 바로가기 [Article Type] Emergency Medicine
Assessment of Attentional Functioning in Health Professionals of a Brazilian Tertiary Referral Hospital for COVID-19Research Article Published on 2021-06-252022-10-28 Journal: Behavioural Neurology [Category] COVID-19, MERS, SARS, [키워드] age Analysis ANCOVA assessment Attention Test Brazil Contact Continuous covariates COVID-19 COVID-19 infection COVID-19 patient cut-off evaluated exposure group group higher risk hospital other variable participant Participants Patient patients patients with COVID-19 performed professional reached Referral remained response responses Rio de Janeiro Sample size SARS-COV-2 infection Sex significantly higher sleep quality statistical significance statistically target Tertiary tertiary referral hospital Variability Visual was performed with COVID-19 [DOI] 10.1155/2021/6655103 PMC 바로가기 [Article Type] Research Article
Pulmonary adverse drug event data in hypertension with implications on COVID-19 morbidityArticle Published on 2021-06-252022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] ACE2 ACEi ACEIs addition ADE ADEs Analysis angiotensin-converting enzyme 2 angiotensin-converting enzyme inhibitor antihypertensive medication Applied mathematics ARB ARBs association blocker Cluster combinations commonality Comorbidity Computational science Computer science confounder covariate COVID-19 database described determine drug evaluated event FDA Health policy hidden Host hypertension implication incidence Infectious diseases Logistic regression analysis morbidity Novel coronavirus Occurrence outcome Pairwise comparison Patient profile public health pulmonary receiving receptor Reporting responsible Retrospective analysis SARS-CoV-2 significant difference significantly higher Spontaneous statistical statistically Statistics underlying disease upregulated [DOI] 10.1038/s41598-021-92734-7 PMC 바로가기 [Article Type] Article