Preclinical assessment and randomized Phase I study of CT-P63, a broadly neutralizing antibody targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Article Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 비임상, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome Beta Blood caused clinically Concentration coronavirus COVID-19 creatine phosphokinase CT-P63 deaths declining Delta demonstrated detectable dose double-blind evaluated groups healthy volunteer Immunity in vitro in vivo Infection Infectious virus lung monoclonal monoclonal antibody morbidity and mortality mutated variant Neutralizing Neutralizing activity neutralizing antibody omicron pandemic parallel-group participant peaked phase Placebo placebo-controlled Preclinical prevalent Prophylactic Randomized reduced respiratory tract Safe SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants of concern Serious Adverse Events significantly single ascending dose study drug TEAE titre Tolerability Transgenic mouse treated Treatment treatment-emergent adverse event vaccination variants variants of SARS-CoV-2 wild-type [DOI] 10.1080/22221751.2022.2117094 PMC 바로가기
Heterologous booster with inhaled adenovirus vector COVID-19 vaccine generated more neutralizing antibodies against different SARS-CoV-2 variantsArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] addition adenoviral vector Adenovirus adenovirus type 5 vector vaccine Anti-RBD IgG booster COVID-19 COVID-19 vaccine D614G demonstrated dose effective Efficacy IgA immunization Inactivated vaccine Inactivated Vaccines Inhaled lack mucosal Neutralization assay Neutralizing neutralizing antibody omicron Omicron variant BA.5 pandemic plasma Protective RBD SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 vaccines SARS-CoV-2 variant subunit titre Vaccination strategies Vaccination strategy Vaccine variant virus widespread [DOI] 10.1080/22221751.2022.2132881 PMC 바로가기
Disruptions in standard care: anterior cruciate ligament reconstruction outcomes during the SARS-COV2 pandemicArticle Published on 2022-12-012023-07-06 Journal: The Physician and sportsmedicine [Category] COVID19(2023년), [키워드] Anterior cruciate ligament reconstruction pandemic Physiotherapy rehabilitation telehealth [DOI] 10.1080/00913847.2021.1971494
The current scope of the COVID-19 pandemic and its influence on palliative medicineArticle Published on 2022-12-012023-07-11 Journal: Annals of palliative medicine [Category] COVID19(2023년), [키워드] COVID-19 hospitalizations palliative pandemic Vaccine [DOI] 10.21037/apm-22-1440
Dynamics of viral shedding during ancestral or Omicron BA.1 SARS-CoV-2 infection and enhancement of pre-existing immunity during breakthrough infectionsArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] addition Anti-RBD IgG antibody Breakthrough infection Cell cellular immunity cellular response circulating Delta Diagnosis Dynamics exhibited faster greater HCW HCWs healthcare worker humoral IFN-γ Immunity Infection infectiousness investigated isolates median neutralization capacity neutralizing antibody titre normalized omicron pandemic positive pre-existing immunity proportion reported RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 isolates SARS-CoV-2 peptides SARS-CoV-2 variants symptom onset Vaccine vaccine-immunity variant viral clearance viral culture Viral load viral loads viral shedding [DOI] 10.1080/22221751.2022.2122578 PMC 바로가기
COVID-19: imbalanced cell-mediated immune response drives to immunopathologyArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome alveolar damage Antiviral caused cell-mediated immune cell-mediated immune response changes in consequence coronavirus coronavirus disease COVID-19 Critical cytokine Cytokine storm effective Endotheliitis exacerbated excessive inflammation fluid overload homeostasis Host host cells immune immune responses immune system Immunological response immunopathology Inflammatory response Invasion involved lung damage Lung injury manifested mechanism NETs neutrophil activation organs pandemic Pathogenesis pathophysiological progression SARS-CoV-2 SARS-CoV-2-specific immune responses severe disease syndrome therapeutic agent Therapeutic strategies tissue Trigger viral infection [DOI] 10.1080/22221751.2022.2122579 PMC 바로가기
Beyond COVID-19: Do biothermodynamic properties allow predicting the future evolution of SARS-CoV-2 variants?Research article Published on 2022-12-012022-10-05 Journal: Microbial Risk Analysis [Category] 변종, [키워드] Analysis binding biological property changes in COVID-19 pandemic driving Epidemiological study Evolution Evolution of SARS-CoV-2 Gibbs energy of binding Gibbs energy of growth growth Mechanistic model MERS-CoV Mutation new strain new virus Occurrence pandemic parameter performed predict risk SARS CoV-2 SARS-CoV statistical Strains the SARS-CoV-2 variants of SARS-CoV-2 Virus-host interaction viruses [DOI] 10.1016/j.mran.2022.100232 [Article Type] Research article
In-silico primer designing and PCR for detection of monkeypox virus (MPXV)Article Published on 2022-12-012023-06-10 Journal: Journal of infection and public health [Category] Fulltext, 원숭이두창, [키워드] Bioinformatics tools pandemic pathology zoonosis [DOI] 10.1016/j.jiph.2022.11.002 PMC 바로가기
The harm in and of COVID-19Article Published on 2022-12-012023-07-06 Journal: Developing world bioethics [Category] COVID19(2023년), [키워드] abortion COVID-19 Economy education Harm pandemic [DOI] 10.1111/dewb.12335 PMC 바로가기
Listening to COVID-19 survivors: what they need after early discharge from hospital – a qualitative studyArticle Published on 2022-12-012023-07-07 Journal: International Journal of Qualitative Studies on Health and Well-being [Category] COVID19(2023년), [키워드] COVID-19 pandemic post-discharge experience qualitative study Survivors [DOI] 10.1080/17482631.2022.2030001 PMC 바로가기