Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack RateVirology Published on 2020-08-212022-10-30 Journal: Journal of Clinical Microbiology [Category] COVID-19, MERS, SARS, [키워드] animal model antibody assays attack attack rate boat correlates COVID-19 cycle threshold Evidence facilitated Fisher’s exact test Fishery Fishing Follow-up follow-up period Human humans immunological individual individuals Infection initial median Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody titer outbreak performed protection protective immunity Rate Reinfection reverse transcription-PCR RT-PCR SARS-CoV-2 Sequencing seroconverted serological seropositive significantly suggested Symptom tested Vaccine vessel viral clade viral genome viral infection viral outbreak yielding [DOI] 10.1128/JCM.02107-20 PMC 바로가기 [Article Type] Virology
Post-mortem viral dynamics and tropism in COVID-19 patients in correlation with organ damage장기 손상과 상관관계가 있는 COVID-19 환자의 사후 바이러스 역학 및 친화성Original Article Published on 2020-08-202022-09-10 Journal: Virchows Archiv [Category] MERS, 진단, 치료기술, 치료법, 치료제, [키워드] age alveolar damage amplification Autopsy bile both lungs Brain bronchial glands bronchopneumonia can not changes correlation COVID-19 COVID-19 patient Ct values cycle threshold death Deceased diagnosed with COVID-19 Diffuse alveolar damage E-gene Gallbladder immunohistochemistry Immunohistochemistry bowel Infarction infected individual infected individuals intestinal epithelium intestine less lung Lungs males median moderate nucleic acid nucleocapsid protein ORF1a/b organ organ damage Patient PCR persistence Pneumocytes positive Post-mortem Potential primer Primers Protein respiratory respiratory tract RNA SARS-CoV-2 SARS-CoV-2 RNA significant increase structural protein supplementary material Swab swabs throat swab thrombosis tissue damage Viral viral dynamics Viral RNA virus [DOI] 10.1007/s00428-020-02903-8 PMC 바로가기 [Article Type] Original Article
Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020Rapid Communication Published on 2020-08-132022-10-31 Journal: Eurosurveillance [Category] COVID-19, Fulltext, MERS, [키워드] acute respiratory syndrome analysed Asymptomatic coronavirus coronavirus disease correlation COVID-19 cycle threshold Cycle threshold value Decline Duration England Infectious virus infectiousness Mild-to-moderate persist public health policy respiratory virus RT-PCR SARS-CoV-2 symptom onset symptomatic upper respiratory tract Viral load virus [DOI] 10.2807/1560-7917.ES.2020.25.32.2001483 PMC 바로가기 [Article Type] Rapid Communication
A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples임상 샘플에서 SARS-CoV-2 RNA를 검출하기 위한 비색 RT-LAMP 분석 및 LAMP 시퀀싱Research Article Published on 2020-08-122022-09-25 Journal: Science Translational Medicine [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome addition amplification caused clinical sample collected coronavirus coronavirus disease COVID-19 Critical cycle threshold detect diagnostic eliminating faster individual Infection investigator isothermal isothermal amplification Large-scale testing less Loop-mediated isothermal amplification N gene outcome pandemic PCR Pharyngeal swab polymerase chain primer protocol public health qPCR Quantitative Rapid reaction Reactions resources retained reverse transcription RNA RNA isolation RNA sample RT-LAMP RT-qPCR SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 RNA detection SARS-CoV-2 viral RNA sensitivity Sensitivity and specificity Sequencing shown specificity specimen temperature tested the SARS-CoV-2 Viral RNA virus spread [DOI] 10.1126/scitranslmed.abc7075 PMC 바로가기 [Article Type] Research Article
Ion torrent-based nasopharyngeal swab metatranscriptomics in COVID-19Short communication Published on 2020-08-012022-10-05 Journal: Journal of virological methods [Category] 유전자 메커니즘, [키워드] bioinformatics Brazil contributed COVID-19 Ctcycle threshold cycle threshold Depletion Ion Local Nasopharyngeal swab Next-generation sequencing NGSNext-generation sequencing Real-time reverse transcription PCR ribosomal RNA RT-qPCRreal-time reverse transcription PCR SARS-CoV-2 genome Single nucleotide polymorphism SNPSingle nucleotide polymorphism Transmission virus [DOI] 10.1016/j.jviromet.2020.113888 [Article Type] Short communication
Time Length of Negativization and Cycle Threshold Values in 182 Healthcare Workers with Covid-19 in Milan, Italy: An Observational Cohort StudyArticle Published on 2020-07-232022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] all age group analyzed Asymptomatic Cohort Control coronavirus 2 Coronavirus disease 2019 COVID-19 Ct value cycle cycle threshold Cycle threshold values evaluate follow-up period HCW HCWs health care workers healthcare worker Infection Length median time N genes onset of symptom positive positive individual positive individuals profile public health emergency Rapid respiratory Result returned reverse transcription PCR RT-PCR SARS-CoV-2 Spread Swab symptomatic tested the SARS-CoV-2 time value Variability Variation with COVID-19 worker [DOI] 10.3390/ijerph17155313 PMC 바로가기 [Article Type] Article
Real-time RT-PCR for COVID-19 diagnosis: challenges and prospectsCOVID-19 진단을 위한 실시간 RT-PCR: 과제 및 전망Review Published on 2020-07-212022-09-10 Journal: The Pan African Medical Journal [Category] MERS, SARS, 치료기술, [키워드] Accuracy Chain Reaction choice clinical sample clinical samples coronavirus CoV COVID-19 COVID-19 diagnosis Critical cut-off cut-off value cycle threshold debatable Diagnosis diagnostic test diagnostic tests Economy effective response global public health Impact Infection Local polymerase chain reaction protocol provide qPCR assays real-time reverse transcriptase-polymerase chain reaction reliability reverse transcriptase RT-PCR RT-qPCR RT-qPCR assay RT-qPCR assays SARS-CoV-2 SARS-CoV-2 detection sports test results [DOI] 10.11604/pamj.supp.2020.35.24258 PMC 바로가기 [Article Type] Review
Non-optimal effectiveness of convalescent plasma transfusion and hydroxychloroquine in treating COVID-19: a case reportCase Report Published on 2020-06-192022-10-28 Journal: Virology Journal [Category] COVID-19, SARS, [키워드] Admission C-reactive protein Case report Chinese combination therapy Computed tomography convalescent plasma COVID-19 Critically ill patient CRP cycle threshold diagnosed effective Effectiveness Hydroxychloroquine in vitro inhibit SARS-CoV-2 intravenously lactic acid oxygenation index oxyhemoglobin saturation plasma positive receiving remained reported returned RNA SARS-CoV-2 severe COVID-19 severe pulmonary lesion suggested temperature therapy throat swab White blood cell with COVID-19 [DOI] 10.1186/s12985-020-01354-6 PMC 바로가기 [Article Type] Case Report
Nasopharyngeal Swabs Are More Sensitive Than Oropharyngeal Swabs for COVID-19 Diagnosis and Monitoring the SARS-CoV-2 LoadMedicine Published on 2020-06-182022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI analyzed Chinese clinical collected coronavirus disease COVID-19 cycle threshold detectable detection detection rate diagnosing droplet evaluated Inpatient less load management median monitoring Nasopharyngeal swab nausea NPs oropharyngeal swab Patient Prospective Study real-time RT-PCR reduce registry reported risk sampling SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleic acid sensitive sensitivity significantly significantly higher significantly lower specimen Swab swabs the SARS-CoV-2 Viral load vomit [DOI] 10.3389/fmed.2020.00334 PMC 바로가기 [Article Type] Medicine
Evaluation of Transport Media and Specimen Transport Conditions for the Detection of SARS-CoV-2 by Use of Real-Time Reverse Transcription-PCRVirology Published on 2020-04-272022-10-30 Journal: Journal of Clinical Microbiology [Category] COVID-19, SARS, [키워드] acute respiratory syndrome aliquot BAL Bronchoalveolar lavage condition coronavirus CoV COVID-19 cycle threshold detection determine disease media medium NaCl pandemic Patient question raised RNA RNA stability SARS-CoV-2 specimen sputum stability storage conditions Swab temperature tested Transport transport conditions Transport media UTM variety viral transport media [DOI] 10.1128/JCM.00708-20 PMC 바로가기 [Article Type] Virology