Virtual screening of approved drugs as potential SARS-CoV-2 main protease inhibitorsResearch article Published on 2020-10-012022-10-05 Journal: Computational biology and chemistry [Category] SARS, 신약개발, [키워드] Analysis approved approved drug binding free energy caused Coverage COVID-19 Critical disease docking drug Drug discovery drugs flexible inhibiting inhibitor inhibitors of SARS-CoV-2 Ligand Molecular dynamics simulation morbidity Mortality MPro nine protease reduce repurposing SARS-CoV-2 SARS-CoV-2 main protease screened tested therapeutic therapeutic target Virtual screening [DOI] 10.1016/j.compbiolchem.2020.107325 [Article Type] Research article
Genopo : a nanopore sequencing analysis toolkit for portable Android devicesArticle Published on 2020-09-292022-10-31 Journal: Communications Biology [Category] COVID-19, SARS, [키워드] Analysis bioinformatics can be used Community Complete computation computational analysis Computational platforms and environments coronavirus SARS-CoV-2 determine DNA and RNA DNA methylation DNA sequencing flexible Genome genome sequence genomes Human genome less Nanopore nine patient isolate performed resource sequenced Sequencing Sequencing analysis sequencing data Tablet toolkit utility [DOI] 10.1038/s42003-020-01270-z PMC 바로가기 [Article Type] Article
COMOKIT: A Modeling Kit to Understand, Analyze, and Compare the Impacts of Mitigation Policies Against the COVID-19 Epidemic at the Scale of a CityPublic Health Published on 2020-09-242022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Against agent-based modeling (ABM) Analysis analyzed appear China city Combination Community computer simulation (CS) containment strategies COVID-19 COVID-19 pandemic dimension disease Effectiveness epidemiological epidemiological modeling Evolution experiment flexible GAMA platform heterogeneity Impact implementation phase in silico Intervention methodology Mitigation modeling pandemic progresses Perspective Policy public health public health authority responses against scale Spread Transmission variety [DOI] 10.3389/fpubh.2020.563247 PMC 바로가기 [Article Type] Public Health
Cascaded deep learning classifiers for computer-aided diagnosis of COVID-19 and pneumonia diseases in X-ray scansOriginal Article Published on 2020-09-222022-10-31 Journal: Complex & Intelligent Systems [Category] COVID-19, [키워드] Accuracy assist Bacterial binary classifier Biomedical image processing CAD Cascaded classifiers Classifier Coronavirus outbreak COVID-19 COVID-19 infection dataset deep learning Dense diagnose Diagnosis diagnosis of COVID-19 diagnostic procedure disease ENhance evaluated flexible group Health status include infected cases network Neural Patient physician Pneumonia pneumonia images powerful tool Previous studies residual second Support tested Visual X-ray [DOI] 10.1007/s40747-020-00199-4 PMC 바로가기 [Article Type] Original Article
COVID-19 in the United States: Trajectories and second surge behaviorFast Track Published on 2020-09-222022-10-31 Journal: Chaos [Category] Coronavirus, SARS, [키워드] Algorithm Analysis approach COVID-19 COVID-19 case determine flexible highlighting mathematical normalized response The United States trajectory [DOI] 10.1063/5.0024204 PMC 바로가기 [Article Type] Fast Track
Assessment of proton-coupled conformational dynamics of SARS and MERS coronavirus papain-like proteases: Implication for designing broad-spectrum antiviral inhibitorsARTICLES Published on 2020-09-212022-10-30 Journal: The Journal of Chemical Physics [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antiviral drug antiviral inhibitor assessment assist calculated catalytic caused computation conformational coronavirus CoV cysteine cysteine protease drug target Evidence flexible GPU Hypothesis inhibitor lack MERS coronavirus MERS-CoV Middle East modulate molecular Outbreaks pandemic Papain-like protease physiological plasticity PLPro Prevent protonation state residue respiratory syndrome coronavirus SARS-CoV SARS-CoV-2 Simulation starting point structure-based design Support supported viral life cycle [DOI] 10.1063/5.0020458 PMC 바로가기 [Article Type] ARTICLES
Flexible, Freely Available Stochastic Individual Contact Model for Exploring COVID-19 Intervention and Control Strategies: Development and SimulationOriginal Paper Published on 2020-09-182022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, SARS, [키워드] Case isolation category Contact Control coronavirus disease country COVID-19 COVID-19 epidemic develop development Dynamics Effect Epidemic epidemic curve feasible FIVE flexible help hypothetical individual Infection infection dynamics Interaction Intervention investigator involved Isolation Local Model moderate objective parameter predicted Probability produced provided Public health intervention Public health interventions public health measure recorded replicate reported representing researcher Result Seven Simulation social distancing social distancing measures Spread statistical stochastic the epidemic [DOI] 10.2196/18965 PMC 바로가기 [Article Type] Original Paper
Tracking and forecasting milepost moments of the epidemic in the early-outbreak: framework and applications to the COVID-19Research Article Published on 2020-09-182022-10-31 Journal: F1000Research [Category] COVID-19, MERS, [키워드] 2019 novel coronavirus available data CDC center China confirmed case Control country COVID-19 COVID-19 outbreak death develop early stage Effectiveness Epidemic Epidemic Development Index System evaluate flexible Forecasting Government help hospital Infectious disease Mild outbreak patients treated Prediction Method question Result Spread the epidemic [DOI] 10.12688/f1000research.23107.2 PMC 바로가기 [Article Type] Research Article
Establishing a high sensitivity detection method for SARS-CoV-2 IgM/IgG and developing a clinical application of this methodSARS-CoV-2 IgM/IgG에 대한 고감도 검출 방법 확립 및 이 방법의 임상 적용 개발Research Article Published on 2020-09-182022-09-10 Journal: Emerging Microbes & Infections [Category] MERS, SARS, 진단, 치료기술, [키워드] Antibody test benefit caused China Clinical course clinical evaluation Clinical significance Combination COVID-19 COVID-19 patients detect disease disease evaluation during treatment Establishing flexible fluorescent Follow-up healthy IgG and IgM IgM and IgG IgM/IgG immunoassay immunochromatographic test lateral flow microsphere multi-epitopes fusion protein Non-COVID-19 outbreak Patient patients Prognosis provided SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody test SARS-COV-2 infection sensitivity specificity Spread test strip test strips time-resolved fluorescence immunoassay Treatment virus was done with COVID-19 Wuhan [DOI] 10.1080/22221751.2020.1811161 PMC 바로가기 [Article Type] Research Article
COD19 and COD20: An Italian Experience of Active Home Surveillance in COVID-19 PatientsArticle Published on 2020-09-142022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Active surveillance acute respiratory syndrome center clinical condition Clinical data COD19 COD20 collected coronavirus coronavirus disease COVID-19 Critical Epidemic experience flexible Health home home surveillance Hospital admission intensive care intrinsically Italian Italy many case numbers of patient operation pandemic Patient platform recognizing required SARS-CoV-2 Satisfaction service System telemedicine service Web [DOI] 10.3390/ijerph17186699 PMC 바로가기 [Article Type] Article