Efficacy and sustainability of natural products in COVID-19 treatment development: opportunities and challenges in using agro-industrial waste from Citrus and appleReview article Published on 2021-08-162022-10-05 Journal: Heliyon [Category] 신약개발, 치료법, [키워드] Apple pomace Citrus Compound coronavirus COVID-19 COVID-19 pandemic detrimental effect Diseases drugs effective environmental stress evaluate evaluated history illness large trial Measures Medicines natural offer pandemic phytotherapy potential benefit produced SARS-CoV-2 Supportive treatment therapeutic option Treatment [DOI] 10.1016/j.heliyon.2021.e07816 [Article Type] Review article
Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain폐 감염과 뇌를 연결하는 SARS-CoV-2의 세포 및 분자 효과Review Published on 2021-08-132022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] Activation alveolar macrophage antibody anticipated autoantibody Brain caused Central nervous system CNS COVID-19 COVID-19 outbreak Cytokine storm detrimental effect Effect evaluate global pandemic hypoxia immune indirect effect Infection infiltration Intensive irreversible damage lung lung capacity microglia neuroinvasion Neuroinvasive neurological Neurological symptom neurons number of infected raising Research respiratory symptoms SARS-CoV-2 severe COVID-19 Spread the SARS-CoV-2 viral disease [DOI] 10.3389/fimmu.2021.730088 PMC 바로가기 [Article Type] Review
Characterization of ACE Inhibitors and AT 1 R Antagonists with Regard to Their Effect on ACE2 Expression and Infection with SARS-CoV-2 Using a Caco-2 Cell ModelArticle Published on 2021-08-102022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] ACE ACE inhibitor ACE2 ACE2 mRNA angiotensin-converting enzyme 2 antagonist AT1 receptor antagonist binding Caco-2 caused Cell cell barrier integrity characterization Concentration concentrations Cytopathic effect detrimental effect drug Effect host cells in vitro induce infection rate Interaction investigated lung damage lung endothelial Model pharmacological Prevent Protein protein expression receptor reduced reducing SARS-CoV-2 SARS-COV-2 infection significantly upregulation virus replication Virus spike [DOI] 10.3390/life11080810 PMC 바로가기 [Article Type] Article
Mental health among healthcare workers and other vulnerable groups during the COVID-19 pandemic and other coronavirus outbreaks: A rapid systematic reviewResearch Article Published on 2021-08-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] affected Attempted suicide children collected Comorbidities conducted coronavirus country COVID-19 COVID-19 pandemic COVID-19 patient detrimental detrimental effect diagnose estimate Evidence Factors group Health healthcare Healthcare system healthcare worker hospital Impact impacts increased risk Intervention lack material mental health mental health problem MOST outbreak pandemic physical PROSPERO database Protective protocol Quality of life Registered reported Result review risk Symptom systematic review systematic reviews thought [DOI] 10.1371/journal.pone.0254821 PMC 바로가기 [Article Type] Research Article
Catastrophic Thromboembolic Syndrome During the COVID-19 PandemicCardiac/Thoracic/Vascular Surgery Published on 2021-08-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Affect anticoagulation aortic thrombus arteries article catastrophic catastrophic thrombosis syndrome characterized Coagulation Coagulation system Coagulopathy COVID-19 COVID19 D-dimer level Deep venous thrombosis detrimental effect Disruption distal dosage DVT female hypercoagulability organ systems Pain pathway predict presenting Prophylactic reported Respiratory disease risk SARS-CoV-2 shown stroke suffered syndrome the SARS-CoV-2 thromboembolic disease Thromboembolism thrombosis Thrombus Vascular venous thromboembolic [DOI] 10.7759/cureus.16854 PMC 바로가기 [Article Type] Cardiac/Thoracic/Vascular Surgery
Safety of tocilizumab in COVID-19 pregnant women and their newborn: A retrospective studyCOVID-19 임산부와 신생아에서 토실리주맙의 안전성: 후향적 연구Multicenter Study Published on 2021-08-012022-09-11 Journal: Journal of clinical pharmacy and therapeutics [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Admission adverse event adverse events age Algorithm Azithromycin Beta candidate close monitoring collected Coronavirus-2 Corticosteroid Corticosteroids COVID-19 cytomegalovirus demographics detrimental effect detrimental effects discharge during pregnancy electronic medical records Evolution gestational age hepatotoxicity hospital hospitals Hydroxychloroquine IL-6 IL-6 receptor Infection inflammatory phase information inhibitor interferon interferon beta interquartile range laboratory data Lopinavir Lopinavir/ritonavir maternal safety medical history MOST mother Neonatal Newborn newborn safety other immunosuppressive agent other immunosuppressive agents outcome Patient patients Pregnancy pregnant women radiologic resolved respiratory Result Retrospective study Ritonavir Safety SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe COVID-19 Spanish Tocilizumab tocilizumab administration treated Treatment two patients Viral viral reactivation [DOI] 10.1111/jcpt.13394 PMC 바로가기 [Article Type] Multicenter Study
Cessation of Pulsed Lavage During the SARS-CoV-2 Pandemic: The Effect on Hip Hemiarthroplasty Cement MantlesOrthopedics Published on 2021-08-012022-10-31 Journal: Cureus [Category] COVID-19, [키워드] absolute increase acute respiratory syndrome aerosol-generating procedure association benefit bladder calculated Cambridge Cement clinician Cohen’s kappa coefficient coronavirus COVID-19 demonstrated detrimental detrimental effect Effect equipment Follow-up Guidance Hemiarthroplasty higher risk hip hip hemiarthroplasty hospital lavage Mantle Neck of femur fracture operative p value pandemic Pandemics Patient patients treated performed Personal protective equipment presenting Radiographic Result retrospective risk SARS-CoV-2 SARS-CoV-2-positive patients statistically significant the SARS-CoV-2 treated United Kingdom university was used [DOI] 10.7759/cureus.16809 PMC 바로가기 [Article Type] Orthopedics
Systematic Review on the Mental Health and Treatment Impacts of COVID-19 on Neurocognitive DisordersSystematic Review Published on 2021-07-292022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] addition addressed Anxiety articles clinics Community conducted COVID-19 COVID-19 pandemic database Depression detrimental effect disorder Effect eligibility criteria Exacerbation Google Scholar growth healthcare highlight Impact impacts individual literature review measure medications mental health neurocognitive neurocognitive disorders pandemic practitioners PROTECT psychological symptom Psychological well-being PsycINFO public health reduced resulting retrieved review second Self-isolation Support Symptom systematic review therapeutic therapeutic effect Treatment Web of Science [DOI] 10.3390/jpm11080746 PMC 바로가기 [Article Type] Systematic Review
Sense of coherence, social support and religiosity as resources for medical personnel during the COVID-19 pandemic: A web-based survey among 4324 health care workers within the German Network University MedicineResearch Article Published on 2021-07-262022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] Analysis Anxiety assistant association Coherence correlated COVID-19 COVID-19 pandemic Depression detrimental effect effect size form groups HCW Health care worker identify inventory less Medicine Mental mental health mental symptom mental symptoms mitigate network no correlation Nurses objective outcome pandemic Perceived PHQ-2 physician Physicians psychological Impact regressions Research resource Result retrospective scale sense significantly subgroups Support Symptom Symptoms TPV Transpersonal Trust university were assessed were measured [DOI] 10.1371/journal.pone.0255211 PMC 바로가기 [Article Type] Research Article
Omega-3 Index and Clinical Outcomes of Severe COVID-19: Preliminary Results of a Cross-Sectional StudyCommunication Published on 2021-07-212022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] age analyzed association Blood clinical clinical variables control subject COVID-19 COVID-19 pandemic death deficiency detrimental effect Evidence exhibited healthy Hypothesis index Inflammation information inverse marker mechanical ventilation omega-3 fatty acid Omega-3 fatty acids Omega-3 Index Patient quality-control quartile Result risk Risk factors severe COVID-19 Sex stratified subjects Support the healthy with COVID-19 [DOI] 10.3390/ijerph18157722 PMC 바로가기 [Article Type] Communication