Molecular targets and system biology approaches for drug repurposing against SARS-CoV-2Review Published on 2020-11-192022-10-28 Journal: Bulletin of the National Research Centre [Category] COVID-19, [키워드] approach can be used COVID-19 COVID-19 disease creating drug drug candidate Drug repurposing drug target drug targets drugs help host cell surface identify information Interaction network network analysis network biology non-structural protein pandemic provide receptors SARS-CoV-2 System biology target targets Virtual screening virus WHO [DOI] 10.1186/s42269-020-00444-3 PMC 바로가기 [Article Type] Review
Targeting Crucial Host Factors of SARS-CoV-2Review Published on 2020-10-282023-06-14 Journal: ACS Infectious Diseases [Category] MERS, SARS, [키워드] coronavirus COVID-19 drug targets host factors inhibitors SARS-CoV-2 [DOI] 10.1021/acsinfecdis.0c00456 PMC 바로가기 [Article Type] Review
COVID-19: molecular targets, drug repurposing and new avenues for drug discoveryReview Published on 2020-10-022022-10-29 Journal: Memórias do Instituto Oswaldo Cruz [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome candidate caused contagious infection coronavirus Coronavirus disease 2019 Cost effectiveness COVID-19 Critical Drug discovery Drug repurposing drug targets effort Healthcare system Infection knowledge mechanism molecular presenting replication cycle SARS-CoV-2 target targets Treatment [DOI] 10.1590/0074-02760200254 PMC 바로가기 [Article Type] Review
Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatmentsArticle Published on 2020-08-082022-10-04 Journal: International immunopharmacology [Category] MERS, SARS, 비임상, 신약개발, 치료법, 치료제, [키워드] Anakinra Antiviral strategies antiviral strategy approach benefit Coronavirus disease 2019 COVID-19 COVID-19 patients develop drug targets Effect effective therapy effort EIDD-2801 etiological agent exhibited immunological Immunological approaches information inhibitory effect notable pandemic pathogenesis of COVID-19 patients with COVID-19 pharmacologic treatment provide recent Remdesivir SARS-CoV-2 SARS-CoV-2 virus shown Spread targets therapy Treatment virus [DOI] 10.1016/j.intimp.2020.106885 PMC 바로가기 [Article Type] Article
COVID-19: A review of the proposed pharmacological treatmentsArticle Published on 2020-08-062023-06-15 Journal: European journal of pharmacology [Category] MERS, [키워드] clinical trials coronavirus COVID-19 drug targets mechanism of action SARS-CoV-2 [DOI] 10.1016/j.ejphar.2020.173451 PMC 바로가기
Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virusArticle Published on 2020-07-042023-07-01 Journal: European journal of pharmacology [Category] SARS, [키워드] clinical trials COVID-19 drug targets re-purposing SARS-CoV2 Vaccines [DOI] 10.1016/j.ejphar.2020.173348 PMC 바로가기 [Article Type] Article
Tackling SARS-CoV-2: proposed targets and repurposed drugsReview Published on 2020-06-222022-10-31 Journal: Future Medicinal Chemistry [Category] COVID-19, SARS, [키워드] absence Abstract antivirals clinical trials complex interaction COVID-19 described drug drug candidate drug targets drugs fatality health emergency Host identifying mechanism molecular pathogenesis of SARS-CoV-2 Repurposed drug Repurposed drugs SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic target targets the WHO therapeutic option Therapeutics treat Vaccine [DOI] 10.4155/fmc-2020-0147 PMC 바로가기 [Article Type] Review
Identification of essential exported Plasmodium falciparum protein kinases in malaria-infected red blood cellsarticle Published on 2020-03-312024-09-01 Journal: British Journal of Haematology [Category] 말라리아, [키워드] drug targets FIKK kinases kinases malaria Plasmodium falciparum red blood cells [Article Type] article
Drug targets for corona virus: A systematic reviewSystematic Review Published on 2020-03-112023-06-14 Journal: Indian journal of pharmacology [Category] MERS, SARS, [키워드] coronavirus drug targets Middle East respiratory syndrome Severe acute respiratory syndrome [DOI] 10.4103/ijp.IJP_115_20 PMC 바로가기 [Article Type] Systematic Review
Investigating the human protein-host protein interactome of SARS-CoV-2 infection in the small intestineOriginal Article Published on 2020-01-012022-10-31 Journal: Gastroenterology and Hepatology From Bed to Bench [Category] COVID-19, [키워드] ACE2 Antiviral association biological processes Biomarker categories COVID-19 patients database digestion disease DPP4 drug candidate drug targets drug-target interaction element expression functional Gastrointestinal symptom HNF1A HNF1B HNF4A host protein identify IMPROVE Infection Inflammation Interaction interactome investigated mechanism mechanisms MEP1A MEP1B Ontology organ pathway Pathways potential mechanism PPI Protein protein interaction Protein interaction network protein-protein interaction Public receptor ACE2 Regulatory regulatory network SARS-CoV-2 SARS-COV-2 infection small intestine the SARS-CoV-2 therapeutic target tissue transcription factor transcription factors Treatment strategies were used XPNPEP2 PMC 바로가기 [Article Type] Original Article