Kaposi’s Sarcoma-Associated Herpesvirus, but Not Epstein-Barr Virus, Co-infection Associates With Coronavirus Disease 2019 Severity and Outcome in South African PatientsMicrobiology Published on 2022-01-062022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] addition adjusted African age Associate Cape Cohort coronavirus 2 COVID-19 COVID-19 disease severity COVID-19 patient COVID-19 patients COVID-19 severity death detectable died disease DNA EBV Enrollment Epstein-Barr virus herpesvirus HIV HIV positive Human Infection KSHV lytic reactivation median age men Non-communicable disease outcome Oxygen therapy pandemic Patient PCR-confirmed Peripheral blood prevalent respiratory SARS-CoV-2 SARS-COV-2 infection serology seropositive Sex South South Africa supportive care synergy the WHO These data town Tuberculosis viral infection Viral load virus while women [DOI] 10.3389/fmicb.2021.795555 PMC 바로가기 [Article Type] Microbiology
Vascular Damage, Thromboinflammation, Plasmablast Activation, T-Cell Dysregulation and Pathological Histiocytic Response in Pulmonary Draining Lymph Nodes of COVID-19COVID-19의 폐 배수 림프절에서 혈관 손상, 혈전 염증, 원형질모세포 활성화, T-세포 조절 장애 및 병리학적 조직구 반응Immunology Published on 2021-12-132022-09-11 Journal: Frontiers in Immunology [Category] SARS, 치료기술, [키워드] accumulation Activation alveolar damage Analysis Autopsy bronchoalveolar lavage sample bronchoalveolar lavage samples CD105 CD36 collected Control COVID-19 COVID-19 case DAD damage demonstrated Depletion Diffuse alveolar damage downregulation Draining draining lymph node dysfunction dysregulated immune response dysregulation EBV enrolled Epstein Barr virus evidence of evidenced expression profiling FIBRIN FLT1 follicular follicular hyperplasia FOXP3 Gene expression profiling germinal centers herpes Herpes virus herpes viruses histology HLH immunohistochemical staining immunological immunopathology incidence infectious mononucleosis initial LEF1 lymph Lymph node lymph nodes Macrophage macrophage activation marker maturation Microarray microthrombi Migration mounted node Panel pathological pathway peribronchial Peripheral blood phenotype plasmablast plasmablasts positive PROCR provided pulmonary Reactivation response responsible Sample SARS-CoV-2 selected severe COVID-19 staining T-cell T-cell dysregulation T-cells TEK Thromboinflammation thrombosis tissue tracheal upregulation viruses vWF was performed widespread [DOI] 10.3389/fimmu.2021.763098 PMC 바로가기 [Article Type] Immunology
Virus infection induced pulmonary fibrosisReview Published on 2021-12-072022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Avian Influenza CMV contribute cytomegalovirus EBV Epstein–Barr virus Factor fibrosis heterogeneous HIV Human immunodeficiency virus Infection Interstitial lung disease leukemia mechanism mechanisms Middle East outbreak Potential anti-fibrotic therapy pulmonary pulmonary fibrosis respiratory SARS-CoV-2 T-cell target therapy treat virus virus infection [DOI] 10.1186/s12967-021-03159-9 PMC 바로가기 [Article Type] Review
Development of T-cell immunity in a liver and hematopoietic stem cell transplant recipient following coronavirus disease 2019 infection2019년 코로나바이러스 감염에 따른 간 및 조혈모세포 이식 수혜자의 T세포 면역 발달Case Reports Published on 2021-11-012022-09-12 Journal: Cytotherapy [Category] MERS, SARS, 진단, [키워드] 229E affected Allogeneic antibody Antigen antigens Cell cellular immunity CMV comparable comprehensive analysis coronavirus disease Coronaviruses COVID-19 COVID-19 infection development EBV HCoV HCoVs healthy donor High-risk patients highlight HKU1 human coronavirus immunological protection Immunosuppression Immunotherapy in vitro Infection initial less liver Liver transplantation membrane Mild NL63 OC43 organ Organ transplant outbreak Patient patients with comorbidities Peripheral blood Post-infection reactivity recipient Reinfection responses against retained risk stratification robust SARS-CoV2 SCT spike survivor T cell T cell assay T cell memory T cells T-cell immunity the patient Transplant umbilical upper respiratory symptom viruses [DOI] 10.1016/j.jcyt.2021.05.005 PMC 바로가기 [Article Type] Case Reports
Multiple Sclerosis and SARS-CoV-2: Has the Interplay Started?다발성 경화증과 SARS-CoV-2: 상호 작용이 시작되었습니까?Review Published on 2021-09-272022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, [키워드] acute COVID-19 association Central nervous system Chronic illness clinician complex interaction COVID-19 current dissect EBV EBV—Epstein-Barr Virus effort endogenous ENhance environmental factor Epstein-Barr virus Evidence genetic background HERVs Human human endogenous retroviruses immune immune system Infection interfere knowledge mechanism mechanisms Multiple multiple sclerosis natural history Neuroinflammation Novel coronavirus Occurrence pathophysiological Perspective retrovirus review SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 vaccination sclerosis severity Therapeutic strategies therapeutic strategy triggering vaccination Vaccine Viral viral infections virus Virus-host interactions viruses with COVID-19 [DOI] 10.3389/fimmu.2021.755333 PMC 바로가기 [Article Type] Review
Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumoniaCase Report Published on 2021-09-272022-10-28 Journal: BMC Pulmonary Medicine [Category] COVID-19, Fulltext, SARS, [키워드] acute respiratory syndrome affected Alveolar-pleural fistula ARDS Bacterial clinical consequence complex interaction coronavirus 2 COVID-19 EBV effective Endobronchial Endobronchial valve feasible ICU Infection Inflammation Injury invasive Invasive mechanical ventilation Klebsiella pneumoniae lung parenchyma lung tissue management mechanical ventilation Patient patients persistent Pneumonia Pneumothorax Respiratory failure SARS-CoV-2 Serious Adverse Events severity Stage subset therapeutic option treated [DOI] 10.1186/s12890-021-01653-w PMC 바로가기 [Article Type] Case Report
Impaired Antibody-Dependent Cellular Cytotoxicity in a Spanish Cohort of Patients With COVID-19 Admitted to the ICUICU에 입원한 COVID-19 환자의 스페인 코호트에서 손상된 항체 의존성 세포 세포 독성Observational Study Published on 2021-09-202022-09-11 Journal: Frontiers in Immunology [Category] SARS, 임상, 진단, 치료기술, [키워드] analysed antibody antibody-dependent cell-mediated cytotoxicity antibody-dependent cellular cytotoxicity (ADCC) B cell B cells cause Cell-mediated cytotoxicity Clinical management CMV CMV reactivation COVID-19 COVID-19 severity Critical Critical disease critical patient critical patients cytotoxicity detectable EBV EBV reactivation elicited enhanced Gender herpesvirus Hospitalization Hospitalized HSV-1 humoral immune response Humoral response ICU IgG level immune response immunologic response immunologic responses Impaired individuals levels of antibody male memory Mild mild patient mild patients neutralization ability outcomes pandemic parameter Patient Phenotypes plasma recruited SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibodies severe disease Severe patient severe patients significantly Spain Spanish subjects symptomatic Viremia [DOI] 10.3389/fimmu.2021.742631 PMC 바로가기 [Article Type] Observational Study
Stress-Induced Epstein-Barr Virus ReactivationReview Published on 2021-09-182024-09-02 Journal: Biomolecules [Category] 대상포진, [키워드] EBV latency Reactivation Stress vaccination [DOI] 10.3390/biom11091380 PMC 바로가기 [Article Type] Review
Clinical characteristics and outcomes of critically ill patients with acute COVID-19 with Epstein-Barr virus reactivation엡스타인-바 바이러스 재 활성화를 가진 급성 코비드 -19를 가진 중환자 환자의 임상 적 특성 및 결과Research Article Published on 2021-09-152022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] acute COVID-19 albumin ARDS baseline data calcium Characteristics clinical clinical condition collected COVID-19 patient COVID-19 patients Critically ill patient CRP D-dimer EBV epidemiological Epstein-Barr virus had more incidence Infection intensive care intensive care unit lab Laboratory laboratory examination lymphocyte mortality rate no significant difference No. 3 outcome Patient patients with COVID-19 procalcitonin Prognosis prognosis of patient Respiratory failure Result retrospective SARS-CoV-2 serum calcium significantly significantly higher single-center study Supportive treatment tachypnoea the patient Treatment two groups virus were infected Wuhan [DOI] 10.1186/s12879-021-06638-y PMC 바로가기 [Article Type] Research Article
Affinity Tag Coating Enables Reliable Detection of Antigen-Specific B Cells in Immunospot AssaysArticle Published on 2021-07-212022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] affinity affinity tag antibody antibody-secreting cell Antigen antigen coating antigen-specific antibody antigen-specific B cell antigens approach ASC assessment B-cell coating Cohort COVID-19 vaccinations detection Donor EBV Efficiency effort engage facilitate FluoroSpot functional HCMV hexahistidine Humoral immunity Hypothesis immune Immune monitoring immune protection ImmunoSpot infectious agent Influenza information membrane memory B cell memory B-cell non-specific plasmablast platform Prevent protein concentration provide Re-infection Receptor binding domain Recombinant protein reduction in required response SARS-CoV-2 SARS-COV-2 infection secondary antibody sensitivity serum significantly single-cell spike Streamline Tag tested these cell Viral antigen [DOI] 10.3390/cells10081843 PMC 바로가기 [Article Type] Article