higher infectivity
[용어속성] Term
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape
SARS-CoV-2 501Y.V2 변이체는 더 높은 감염성은 없지만 면역 탈출은 있습니다
Article
[키워드] 501Y.V2
Abstract
caused
Cell
cell type
cell types
cells
convalescent
convalescent patient
Convalescent patients
dominant
E484K
Efficacy
escaped
except for
exhibit
experiment
hACE2
higher infectivity
Immune escape
immunized
immunized mice
increase in
individuals
Infectivity
inhibitory effect
Inhibitory effects
K417N
lack
mACE2
mice
monoclonal antibodies
monoclonal antibody
multiple mutation
multiple mutations
murine
Mutation
N501Y
N501Y mutation
neutralization
neutralization ability
neutralizing antibody
neutralizing monoclonal antibodies
neutralizing monoclonal antibody
polyclonal antibodies
polyclonal antibody
Pseudotyped virus
Pseudotyped viruses
receptor binding region
Receptor-binding domain
reduced
SARS-CoV-2
sera
significantly
South Africa
Spike protein
susceptibility
the receptor-binding domain
Vaccines
variant
variant of SARS-CoV-2
variants
variants of SARS-CoV-2
Viral
viral spike protein
viruses
[DOI] 10.1016/j.cell.2021.02.042 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.cell.2021.02.042 PMC 바로가기 [Article Type] Article
Functional comparison of SARS-CoV-2 with closely related pangolin and bat coronaviruses
Article
[키워드] acute respiratory syndrome
Amino acid
antigenicity
Autoimmunity
bat coronavirus
bioinformatics
cathepsin
cell lines
cells
Cluster
coronavirus
Coronaviruses
cross-neutralization
Extensive
higher infectivity
Host
humans
include
infect
Infection
RaTG13
SARS-CoV-2
the SARS-CoV-2
the spike protein
TMPRSS2
variety
viruses
zoonose
[DOI] 10.1038/s41421-021-00256-3 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41421-021-00256-3 PMC 바로가기 [Article Type] Article
Pan-India novel coronavirus SARS-CoV-2 genomics and global diversity analysis in spike protein
Research Article
[키워드] ACE
ACE2
Analysis
antibodies
antibody
Belgium
binding
binding domain
circulating
clades
Comparative genomics
Consensus
country
COVID-19
D614G
docking
enzyme
expected
EY6A
Fatality rate
France
Genome
higher affinity
higher fatality rate
higher infectivity
India
infection rates
Interaction
isolate
isolates
Italy
lowest
Molecular dynamics simulation
mortality rate
Mutation
N439K
Neutralizing antibodies
neutralizing monoclonal antibodies
novel coronavirus SARS-CoV-2
pandemic
Pathogenesis
Prevalence
prevalent
RBM
reactivity
receptor
Receptor binding domain
receptor binding motif
reported
SARS-CoV-2
SARS-CoV-2 genome
SARS-CoV-2 virus
Spike protein
Support
USA
variant
virulence
Wuhan-1
[DOI] 10.1016/j.heliyon.2021.e06564 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1016/j.heliyon.2021.e06564 PMC 바로가기 [Article Type] Research Article
Free SARS-CoV-2 Spike Protein S1 Particles May Play a Role in the Pathogenesis of COVID-19 Infection
무료 SARS-CoV-2 스파이크 단백질 S1 입자는 COVID-19 감염의 병인에서 역할을 할 수 있습니다
Hypothesis
[키워드] accompanied
ACE
ACE2
angiotensin
angiotensin (1-7)
Angiotensin II
Angiotensin-converting enzyme
angiotensin-converting enzyme 2
association
caused
Cell
cell surface
circulation
cleavage site
COVID-19
COVID-19 disease
COVID-19 infection
COVID-19 pathogenesis
D614G
D614G mutation
decrease
disease
downregulate
downregulated
Effect
expression
fraction
Free
furin
furin protease
higher infectivity
Hypothesis
Imbalance
in vivo
infected cell
infected cells
Infection
Inflammation
investigated
lack
lead
less
lung
Lungs
membrane-bound
murine model
mutant
natural infection
Particle
Pathogenesis
pathogenesis of COVID-19
Prevalence
Protein
pulmonary damage
receptor-binding domains
Recombinant spike protein
Renin
renin-angiotensin system
reported
role
S protein
S1 and S2
S1 subunit
S1 subunit shedding
SARS-CoV virus
SARS-CoV-2
SARS-CoV-2 S protein
SARS-CoV-2 strain
separation
severity
shown
spike
Spike protein
subunits
the cell
the receptor-binding domain
the S protein
the S1 subunit
the SARS-CoV-2
thrombosis
trimer
unlikely
Viral
Viral load
virion
virions
wild type
[DOI] 10.1134/S0006297921030032 PMC 바로가기 [Article Type] Hypothesis
[DOI] 10.1134/S0006297921030032 PMC 바로가기 [Article Type] Hypothesis
A Founder Effect Led Early SARS-CoV-2 Transmission in Spain
스페인에서 초기 SARS-CoV-2 전파를 주도한 파운더 효과
Genetic Diversity and Evolution
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
analyses
Analysis
Bayesian
characterized
clade
clades
Cluster
coronavirus
country
COVID-19
COVID-19 case
D614 variant
D614G
D614G substitution
diffusion
displaying
dissemination
Effect
Europe
European country
explosion
FIVE
founder effect
higher infectivity
independent
majority
maximum-likelihood
MOST
Multiple
occurred
ORF8
pandemic
phylodynamic
phylodynamics
Phylogenetic
phylogenetic analyses
phylogeography
Prevalence
prevalent
pseudotyped virion
pseudotyped virions
Region
replaced
REPLACED BY
respiratory
S gene
SARS-CoV-2
SARS-CoV-2 pandemic
SARS-CoV-2 spike protein
sequence
sequences
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
Spain
Spike protein
the epidemic
the SARS-CoV-2
the spike protein
transmitted
variant
virus
viruses
whole-genome
Whole-genome sequence
Wuhan
Wuhan, China
[DOI] 10.1128/JVI.01583-20 PMC 바로가기 [Article Type] Genetic Diversity and Evolution
[DOI] 10.1128/JVI.01583-20 PMC 바로가기 [Article Type] Genetic Diversity and Evolution
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
Review
[키워드] ACE2
against SARS-CoV
angiotensin-converting enzyme 2
approach
Betacoronavirus
bind
Care
Characteristics
Coronaviruses
COVID-19
develop
died
ENhance
higher infectivity
host cell
host receptor
Incubation period
MERS-CoV
outbreak
Potential
Protein
Protein-based vaccines
public health
Replication
SARS-CoV
SARS-CoV-2
SARS-CoV-2 spike
shown
spike
Spike protein
target
the S protein
therapeutic
USA
Vaccine
Vaccine design
Vaccine development
viral entry
virus
[DOI] 10.1016/j.virusres.2020.198141 PMC 바로가기 [Article Type] Review
[DOI] 10.1016/j.virusres.2020.198141 PMC 바로가기 [Article Type] Review
Treatment Options for COVID-19: A Review
Medicine
[키워드] acute respiratory syndrome
analyses
antimicrobial agent
antimicrobial agents
Antiviral
antiviral agent
caused
chloroquine/hydroxychloroquine
coronavirus
COVID-19
COVID-19 pandemic
detect
disease
Drug repurposing
effective
Efficacy
Evidence
global pandemic
globe
Google Scholar
higher infectivity
highlight
identify
Immunoglobulin
in vitro study
Ivermectin
lower mortality
MERS-CoV
morbidity and mortality
multicenter
option
outbreak
pandemic
Pandemics
Randomized controlled trial
regimen
Remdesivir
retrospective
review
SARS-CoV
SARS-CoV-2
searched
single antiviral agent
Tocilizumab
Treatment
Trial
Vaccine
virus
widespread
[DOI] 10.3389/fmed.2020.00480 PMC 바로가기 [Article Type] Medicine
[DOI] 10.3389/fmed.2020.00480 PMC 바로가기 [Article Type] Medicine
Role of Porcine Aminopeptidase N and Sialic Acids in Porcine Coronavirus Infections in Primary Porcine Enterocytes
Article
[키워드] acid
aminopeptidase
aminopeptidase N
APN
cells
cellular
cellular receptor
Coronavirus infections
Coronaviruses
correlated
determinant
Efficiency
Enterocyte
enterocytes
epidemic diarrhea
expression
gastroenteritis
had no
higher infectivity
Infection
Miller
PEDV
porcine coronavirus
porcine epidemic diarrhea virus (PEDV)
positive
positive cell
receptor
replicated
reported
role
Seven
sialic acid
sialic acids
significant increase
significantly
susceptibility
TGEV
Transmissible gastroenteritis virus (TGEV)
Treatment
virus
[DOI] 10.3390/v12040402 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/v12040402 PMC 바로가기 [Article Type] Article