Pneumococcal Conjugate Vaccine Protection against Coronavirus-Associated Pneumonia Hospitalization in Children Living with and without HIV폐렴구균 결합 백신이 HIV 감염 여부에 관계없이 아동의 코로나바이러스 관련 폐렴 입원에 대한 보호 효과Research Article Published on 2021-01-082022-10-29 Journal: mBio [Category] COVID-19, MERS, 폐렴구균 감염증, [키워드] age Analysis Bacterial infection C-reactive protein children clinical manifestation collected conjugate coronavirus Coronavirus infection Coronaviruses CoV CoV infection CoVs described develop double-blind Efficacy elevated Endemic fatality Frequency HIV Hospitalization Hospitalized human coronavirus Human immunodeficiency virus human pathogen incidence individual Infection infections inflammatory markers Lower respiratory tract nasopharyngeal aspirate New coronavirus observation outcomes pandemic participated PCR PCV9 pediatric placebo recipients placebo-controlled clinical trial pneumococcal pneumococcal conjugate vaccine pneumococcal vaccine Pneumonia Prevalence Prevent procalcitonin procalcitonin level protection Randomized randomized trial recipient reported respiratory infections risk SARS-CoV-2 screened secondary bacterial infection severe cases Streptococcus pneumoniae Vaccine with HIV [DOI] 10.1128/mBio.02347-20 PMC 바로가기 [Article Type] Research Article
Genomic and evolutionary comparison between SARS-CoV-2 and other human coronavirusesArticle Published on 2020-12-052022-11-01 Journal: Journal of virological methods [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome approach characterization clade Clustering codon codon usage complementary coronavirus COVID-19 CpG Dinucleotide suppression ecological niche Evolution genomic heterogeneity highly pathogenic Host human coronavirus human pathogen humans indicated infect Interaction MERS-CoV number pandemic pathogenicity Phylogenetic Phylogenetic analysis phylogenetics Phylogeny SARS-CoV SARS-CoV-2 SARS-CoV-2 genome trimer [DOI] 10.1016/j.jviromet.2020.114032 PMC 바로가기 [Article Type] Article
Seroprevalence of anti‐SARS‐CoV‐2 antibodies in COVID‐19 patients and healthy volunteers up to 6 months post disease onset질병 발병 후 최대 6개월까지 COVID-19 환자 및 건강한 지원자에서 항-SARS-CoV-2 항체의 혈청유병률Clinical Trial Published on 2020-11-102022-08-13 Journal: European Journal of Immunology [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] age Anti‐SARS‐CoV‐2 antibody response Anti‐SARS‐CoV‐2 antibody responses anti‐SARS‐CoV‐2 IgG antibody antibody antibody production Antibody Response Antibody titer Asymptomatic circulating classic Clinical signs COVID‐19 COVID‐19 patient COVID‐19 described detect detectable disease onset Fever healthcare Healthcare workers healthy volunteer highlight hospital human pathogen humoral immune response IgA antibodies IgA antibody IgG IgG antibodies IgM immune response immunological information initial longitudinal analysis men Mild MONITOR neutralising antibody neutralization activity Neutralizing antibodies Patient peaking proportion protective immunity Protein provide quantified rapid increase RBD receptor‐binding domain recognizing reduce remained robust SARS‐CoV‐2 SARS‐CoV‐2 screened Seroprevalence setup Severity of disease Spread subject subjects Symptoms tested the Spike titre titres university virus volunteers were infected [DOI] 10.1002/eji.202048970 PMC 바로가기 [Article Type] Clinical Trial
Epitope similarity cannot explain the pre-formed T cell immunity towards structural SARS-CoV-2 proteinsArticle Published on 2020-11-042022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] beta-coronavirus Blood candidate caused Cell Combination coronavirus Coronaviruses driven by Endemic epitope Epitopes explain generate highest Host human pathogen identify Immunity Immunological memory individual individuals memory MHC offer outbreak pandemic pathogen pathology Protein sequence analyses reactive Replication S-protein SARS-CoV-2 SARS-CoV-2 protein similarity structural protein T cell T cell memory the Coronaviridae the SARS-CoV-2 the SARS-CoV-2 virus uninfected venous viral infection virus Wuhan [DOI] 10.1038/s41598-020-75972-z PMC 바로가기 [Article Type] Article
Potential Cross-Reactive Immunity to SARS-CoV-2 From Common Human Pathogens and Vaccines일반적인 인간 병원체 및 백신의 SARS-CoV-2에 대한 잠재적 교차 반응 면역Immunology Published on 2020-10-162022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, 백일해, 파상풍, [키워드] age antigenic antigens B cell B cell epitope CD4 CD8 children combination vaccine common Coronavirus disease 19 (COVID-19) Coverage COVID-19 COVID-19 pandemic cross-reactive cross-reactive immunity dose DTP vaccine eight elicited epitope Epitopes General population herpesvirus Human human pathogen identify identity Immunity Immunological memory include Infectious disease Influenza virus Neutralizing pathological role pathology pediatric peptide Potential predicted Prevent Protective Protein proteome reactivity receive residues respiratory syncytial virus rhinovirus SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike subject T cell epitope vaccination Vaccinations Vaccine virulent virus [DOI] 10.3389/fimmu.2020.586984 PMC 바로가기 [Article Type] Immunology
The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisalReview Published on 2020-10-152022-10-30 Journal: Natural Products and Bioprospecting [Category] COVID-19, [키워드] Antiviral benefit Cancer chronic disease clinical trial communicable Compound compounds COVID-19 COVID-19 pandemic COVID‐19 diabetes Diseases drug ENhance Health Host immune response human pathogen Immunity increasingly infections Infectious diseases mechanisms MERS natural product Neurological diseases pharmacological physiological polyphenol polyphenols respiratory problem respiratory tract SARS viral infection viral infectious diseases [DOI] 10.1007/s13659-020-00271-z PMC 바로가기 [Article Type] Review
Towards integrated surveillance-response systems for the prevention of future pandemicsOpinion Published on 2020-10-072022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, Fulltext, MERS, SARS, 조류인플루엔자, [키워드] approach Bank contribute COVID-19 pandemic cumulative disease drug engage Evidence Health highest Host Human human pathogen inquiry Integrated surveillance-response Italy means MOST one health outbreak Outbreaks Pandemics pathogen Prevent Research reservoirs risk Surveillance Transdisciplinarity Transmission Vaccines West Nile Virus zoonose zoonoses zoonotic zoonotic origin [DOI] 10.1186/s40249-020-00757-5 PMC 바로가기 [Article Type] Opinion
Structures and dynamics of the novel S1/S2 protease cleavage site loop of the SARS-CoV-2 spike glycoproteinArticle Published on 2020-10-052022-10-30 Journal: Journal of Structural Biology: X [Category] COVID-19, [키워드] ab initio modelling abrogated Abstract cleavage site conformations coronavirus furin cleavage site glycan host cells human pathogen insertion Interaction Molecular dynamics simulation prefusion protease proteolytic cleavage regulate representing S1/S2 SARS-CoV-2 spike glycoprotein spike glycoprotein gene Structure the SARS-CoV-2 therapeutic target viral entry virulent [DOI] 10.1016/j.yjsbx.2020.100038 PMC 바로가기 [Article Type] Article
COVID-19 and Respiratory System Disorders Current Knowledge, Future Clinical and Translational Research Questions10008 Published on 2020-09-222022-10-28 Journal: Arteriosclerosis, Thrombosis, and Vascular Biology [Category] COVID-19, Fulltext, SARS, [키워드] Abstract acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome clinical coronavirus disease Coronavirus-2 COVID-19 current Diaphragm disorder Effect Future highlight human pathogen Infection lung parenchymal Research respiratory Respiratory disease Respiratory failure Respiratory system severe COVID-19 syndrome System the disease Thromboembolism translation Vascular [DOI] 10.1161/ATVBAHA.120.314515 PMC 바로가기 [Article Type] 10008
Zoonotic Diseases: Etiology, Impact, and ControlReview Published on 2020-09-122022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] affected animal anthropogenic Bacteria Consequences Contact Control COVID-19 disease Diseases distribution effective etiology Factor Factors fungi Health Human human pathogen Impact implementation include Infection management measure Migration MOST one health parasites Pathogens prevention Protozoa SARS-CoV-2 transmitted Travel variety viruses zoonoses zoonosis zoonotic zoonotic disease [DOI] 10.3390/microorganisms8091405 PMC 바로가기 [Article Type] Review