Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
중요한 COVID-19는 뚜렷한 백혈구 표현형 및 전사체 패턴과 관련이 있습니다
Article
[키워드] (PD-1
activated
adaptive
Admission
affecting
Alpha
analysed
B cells
B-cell
Bacterial sepsis
Blood
calprotectin
CD25
CD4
CD8 T cells
characterized
classical monocytes
cohort study
collected
comparable
controls
COVID-19
COVID-19 patient
COVID-19 severity
Critical
disease
disease severity
Exhaustion
exhibited
expression
flow cytometry
groups
healthy control
healthy controls
HLA-DR
Hospitalization
immune function
immune functions
Immune phenotype
Immune profile
immune response
Immunity
innate and adaptive immunity
leukocyte
marker
monocyte
Monocytes
mononuclear cell
mononuclear cells
naïve
Non-classical monocytes
pathway
Patient
PBMCs
PD-1
PD-L1
peripheral
Peripheral blood
Peripheral blood mononuclear cells
phenotype
plasma
Prognostic markers
Protein
receptor
reduced
RNA sequencing
SARS-CoV-2
Sepsis
severity
T cell
T cells
T-cell
therapeutic target
therapeutic targets
these cell
These cells
transcript
Transcriptome
transcriptomic
transcriptomics
WHO guideline
with COVID-19
[DOI] 10.1111/joim.13310 PMC 바로가기 [Article Type] Article
[DOI] 10.1111/joim.13310 PMC 바로가기 [Article Type] Article