Linked transmission chains of imported SARS-CoV-2 variant B.1.351 across mainland France, January 20212021년 1월 프랑스 본토 전역에서 수입된 SARS-CoV-2 변종 B.1.351의 연결된 전송 체인Case Reports Published on 2021-04-012022-09-10 Journal: Eurosurveillance [Category] MERS, SARS, 변종, [키워드] African B.1.351 B.1.351 variant Characteristics Cluster comparable COVID-19 described effective Epidemiology FIVE France imported cases Incubation investigation lack measure reported responsible SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants 20H/501Y.V2 South Transmission variant [DOI] 10.2807/1560-7917.ES.2021.26.13.2100333 PMC 바로가기 [Article Type] Case Reports
Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers무증상 SARS-CoV-2 보균자의 신속한 검출을 위한 타액 투스텝Research Article Published on 2021-03-292022-09-10 Journal: eLife [Category] SARS, 치료기술, [키워드] Acidic Asymptomatic carrier described detect virus develop evaluated False positives had no healthy Incubation individual infected individuals Infection infections isothermal amplification Loop-mediated isothermal amplification molecular test Nasal sample no symptoms pre-symptomatic producing protocol reverse transcription Saliva saliva samples SARS-CoV-2 SARS-CoV-2 genome sensitivity specificity Symptom Testing the SARS-CoV-2 genome turn unique university virus were infected [DOI] 10.7554/eLife.65113 PMC 바로가기 [Article Type] Research Article
Effect of Inactivation Methods on SARS-CoV-2 Virion Protein and StructureSARS-CoV-2 비리온 단백질 및 구조에 대한 비활성화 방법의 영향Article Published on 2021-03-262022-09-01 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] Antibody detection assays best biosafety biosafety level Biosafety Level 3 BSL3 comparable conditions conducted coronavirus detectable Effect electron microscopy ELISA Genome heat inactivation impacted inactivated inactivation Incubation Infection investigator investigators less level 3 meet protocol purification reduction Research respiratory resulting risk SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe Acute Respiratory Syndrome Coronavirus -2 Structure Treatment ultraviolet ultraviolet irradiation UV inactivation Viral Viral protein Viral proteins Viral RNA viral RNA quantification viral stocks virion virions virus western blot working [DOI] 10.3390/v13040562 PMC 바로가기 [Article Type] Article
Biophysical analysis of SARS-CoV-2 transmission and theranostic development via N protein computational characterizationN 단백질 계산 특성화를 통한 SARS-CoV-2 전파 및 치료학적 발달의 생물물리학적 분석Review Published on 2021-03-012022-09-11 Journal: Biotechnology progress [Category] SARS, 치료법, [키워드] ACE2 addition aerosol Aerosols Analysis angiotensin Angiotensin-converting enzyme beta coronavirus Characteristics computational approach Computational approaches Contact contact with contaminated surfaces coughing COVID-19 COVID-19 infection Diagnosis droplet effective environmental factors Express external environment followed by generate high-affinity binding Host Human Incubation Infection inhalation intrinsic machine learning molecular molecular dynamics N protein nucleocapsid protein Nucleocapsid proteins nucleocapsid proteins. occur organ organs patients probe provide released respiratory disorder respiratory disorders respiratory droplet Respiratory droplets SARS-CoV-2 SARS-CoV-2 transmission sneezing spread of COVID-19 symptomatic and asymptomatic symptomatic and asymptomatic patients Transmission transmitted Treatment viral infection Viral pneumonia virus viruses zoonotic [DOI] 10.1002/btpr.3096 PMC 바로가기 [Article Type] Review
Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury7-케토콜레스테롤에 의한 내피 손상에 대한 에르고티오네인의 효과Article Published on 2021-03-012022-09-11 Journal: Neuromolecular medicine [Category] 신약개발, [키워드] 7-Ketocholesterol addition animals Anti-inflammatory anti-inflammatory effect Anti-inflammatory effects antioxidant Apoptosis Bacteria blood-brain barrier Blood–brain barrier Brain cardiovascular disease Cell cell viability cholesterol claudin claudin-5 CNS complications coronavirus COVID-19 COX2 cross Cyclooxygenase Cytokines Dementia diabetes diet Diseases dose-dependent Effect Eicosanoids Endothelial cell endothelial cells enzymatic activity Ergothioneine excitotoxicity Extracellular Free Free radicals fungi Human brain humans IL-1β IL-6 IL-8 increase in increases in Incubation induce Inflammation inhibitor management mRNA expression Mushrooms Necrosis neurodegenerative Neuroinflammation neurologic Neurovascular Neutralizing NF-kB nucleus nutraceutical oxidative stress Oxysterols Patient pro-inflammatory cytokines produced protective effect Proteins reduced significantly stroke thought tight junction Tight junction proteins TNF-α unlikely Vascular vascular dementia viability ZO-1 zonula zonula occludens [DOI] 10.1007/s12017-020-08620-4 PMC 바로가기 [Article Type] Article
The distribution of SARS-CoV-2 contamination on the environmental surfaces during incubation period of COVID-19 patientsCOVID-19 환자의 잠복기 동안 환경 표면에 대한 SARS-CoV-2 오염 분포Article Published on 2021-01-152022-09-11 Journal: Ecotoxicology and environmental safety [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 bathroom bedroom collected Contamination coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 patient detect distribution environmental contamination environmental factor environmental factors functional had no in viral Incubation Incubation period living room medium patients polyester positive rate positive rates positive sample quarantine respiratory role SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tested Transmission Transport transport medium Viral Viral transport medium [DOI] 10.1016/j.ecoenv.2020.111438 PMC 바로가기 [Article Type] Article
Rapid SARS-CoV-2 Detection Using Electrochemical Immunosensor전기화학적 면역센서를 사용한 신속한 SARS-CoV-2 검출Article Published on 2021-01-082022-09-10 Journal: Sensors (Basel, Switzerland) [Category] 진단, 치료기술, [키워드] 2019-nCoV Analysis anti-spike antibodies Antigen binding biosensor caused Concentration Corona coronavirus coronavirus disease COVID-19 detect detection determine develop Diagnosis diagnostic test diagnostic tests diagnostics electrochemical sensing faster ferrocyanide Graphene Health crisis identify immunoassay immunosensor Incubation infected individual infected individuals Infection international public health limit Novel coronavirus outbreak pandemic qPCR Rapid Recombinant spike protein SARS-CoV-2 SARS-CoV-2 virus sensor significantly Spike protein Spread subunit surface protein the spike protein Treatment virus voltammetry was used [DOI] 10.3390/s21020390 PMC 바로가기 [Article Type] Article
Aerosol transmission, an indispensable route of COVID-19 spread: case study of a department-store clusterResearch Article Published on 2020-12-252022-10-31 Journal: Frontiers of Environmental Science & Engineering [Category] COVID-19, [키워드] activities aerosol transmission analyzed Characteristics China Cluster COVID-19 Department dependent on environmental condition environmental factor Epidemiologic characteristic epidemiological Factor Figuring Hospitalization Incubation indicated Infection route Isolation median occur outbreak outbreak sites Patient released respiratory tract RNA SARS-CoV-2 Spread SRAS-CoV-2 temperature the SARS-CoV-2 Transmission unique Ventilation widespread with COVID-19 [DOI] 10.1007/s11783-021-1386-6 PMC 바로가기 [Article Type] Research Article
Methods of Inactivation of SARS-CoV-2 for Downstream Biological AssaysMajor Article Published on 2020-08-152022-10-29 Journal: The Journal of Infectious Diseases [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Biological cells coronavirus coronavirus disease COVID-19 detergents disease downstream effective strategy experiments facilitate heat inactivated inactivation Incubation infected cell infectious sample methanol pandemic paraformaldehyde protocol reagent reagents reduce Research researcher Safe SARS-CoV-2 SARS-CoV-2 research Scientific community temperature tested transfer Trizol virus [DOI] 10.1093/infdis/jiaa507 PMC 바로가기 [Article Type] Major Article
Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA바이러스 RNA를 추출하지 않고 비인두 표본에서 직접 RT-qPCR에 의한 SARS-CoV-2 RNA 검출Research Article Published on 2020-07-242022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] Accuracy analytical sensitivity approach circumvent collected condition demonstrated detect detection develop direct approach expand help Incubation Laboratory limit of detection master mix medium nasopharyngeal specimen Nasopharyngeal swab nasopharyngeal swabs other conditions other coronavirus other coronaviruses PCR Pearson correlation coefficient positive positively correlated protocol provide reagents reproducibility resource RNA extraction RT-qPCR RT-qPCR assay RT-qPCR assays RT-qPCR master mixes SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 testing sensitivity specificity specimen submitted TaqPath tested Transport Variation Viral Viral RNA virus [DOI] 10.1371/journal.pone.0236564 PMC 바로가기 [Article Type] Research Article