Chronic diseases, chest computed tomography, and laboratory tests as predictors of severe respiratory failure and death in elderly Brazilian patients hospitalized with COVID-19: a prospective cohort studyResearch Published on 2022-02-172022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] adjusted adults hospitalized age Anemia association Atrial fibrillation C-reactive protein Cancer Chest computed tomography Chest CT chronic Chronic diseases collected COVID-19 CRP death determine Diseases elderly hemoglobin Hospitalization Hospitalized independent predictor independent risk factor Laboratory test Laboratory tests lung involvement mechanical ventilation men Mortality objective occurred Older patients hospitalized predictor progression prospective cohort prospective cohort study pulmonary involvement Regression analyses Respiratory failure Result risk factor severe respiratory failure Vitamin Vitamin D with COVID-19 [DOI] 10.1186/s12877-022-02776-3 PMC 바로가기 [Article Type] Research
Self-reported symptom study of COVID-19 chemosensory dysfunction in MalaysiaArticle Published on 2022-02-082022-10-04 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, [키워드] accounted adult COVID-19 patient aetiology alteration Analysis Asian changes in chemesthesis chemosensory Cohort conducted COVID-19 cross-sectional diagnosed with COVID-19 disorder dominant dysfunction entire cohort Epidemiology implicated independent predictor loss of appetite Malaysia mechanism multicentre nasal Olfactory system Patient patients Perceived Population presenting presenting symptom Prevalence proportion questionnaire reduction in reported sensorineural Signs and symptoms Symptom these symptoms Variation viral infection viral strains widespread [DOI] 10.1038/s41598-022-06029-6 PMC 바로가기 [Article Type] Article
In Patients with Severe COVID-19, the Profound Decrease in the Peripheral Blood T-Cell Subsets Is Correlated with an Increase of QuantiFERON-TB Gold Plus Indeterminate Rates and Reflecting a Reduced Interferon-Gamma ProductionArticle Published on 2022-02-072022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] Analysis CD3 CD3+ CD4/CD8 CD4+ CD8+ Characteristics COVID-19 COVID-19 patients demonstrated gold GraphPad Prism hospitalized COVID-19 patient hospitalized COVID-19 patients IFN IFN-γ IGRA increase Increased independent predictor indeterminate lymphopenia median multivariable analysis non-survivor Non-survivors oxygen supply Patient patients patients hospitalized peripheral Peripheral blood positive correlation Prevalence Production QuantiFERON-TB Gold Rate Reflecting required Retrospective study SARS-CoV-2 severe cases severe COVID-19 patient stratified survivor T-cell T-lymphocyte to define was performed [DOI] 10.3390/life12020244 PMC 바로가기 [Article Type] Article
“H” is not for hydroxychloroquine—“H” is for heparin: lack of efficacy of hydroxychloroquine and the role of heparin in COVID-19—preliminary data of a prospective and interventional study from Brazil"H"는 하이드 록시 클로로 퀴인을위한 것이 아닙니다. "H"는 헤파린을위한 것입니다 : 하이드 록시 클로로 퀴인의 효능 부족과 COVID-19에서 헤파린의 역할-브라질의 전향 적 및 중재 연구의 예비 데이터Research Published on 2022-02-042022-09-10 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, SARS, 치료제, [키워드] absence Admission advanced age antiviral efficacy benefit Brazil Comorbidities Comorbidity COVID-19 COVID-19 pandemic curative demonstrated determine diagnosed with COVID-19 drug Efficacy Endotracheal intubation evaluate HCQ health problem heparin hospital Hospitalized Hydroxychloroquine ICU ICU admission immunomodulatory properties immunomodulatory property in vitro experiments in vivo independent independent predictor independent predictors lack male male predominance mechanical ventilation median age morbidity and mortality Mortality Multivariate analysis no difference outcome outcomes Patient patients hospitalized patients treated predict predictor Prognostic factor Prognostic factors Prophylactic public health reducing mortality Result RT-PCR single-center therapeutic Univariate analysis with COVID-19 [DOI] 10.1186/s12879-022-07110-1 PMC 바로가기 [Article Type] Research
Reactivation of Herpes Simplex Virus Type 1 (HSV-1) Detected on Bronchoalveolar Lavage Fluid (BALF) Samples in Critically Ill COVID-19 Patients Undergoing Invasive Mechanical Ventilation: Preliminary Results from Two Italian CentersBrief Report Published on 2022-02-042022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] antiviral therapy Antiviral treatment association BALF bronchoalveolar center coronavirus disease COVID-19 COVID-19 patient criteria Critically ill patient cumulative risk described Herpe herpes simplex herpes simplex virus HSV-1 Ill independent predictor intensive care intravenous intubated patient Italian lavage Mechanical Mortality Patient Pneumonia predictor prognostic Reactivation Respiratory function Result retrospective Sample SARS-CoV-2 study inclusion Type Ventilated virus with COVID-19 worsening [DOI] 10.3390/microorganisms10020362 PMC 바로가기 [Article Type] Brief Report
Social Determinants and COVID-19 in a Community Health Center CohortCommunity Health Center 코호트의 사회적 결정 요인 및 COVID-19Article Published on 2022-02-012022-09-11 Journal: Journal of immigrant and minority health [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval adjusted adjusted odds ratio Analysis Care center Cohort Community community health Community Health Center Community health centers conducted COVID-19 demographic factor Demographic factors demonstrated determinant English Health health center Hispanic identify independent independent predictor independent predictors individuals less Logistic regression main analysis multi participant Patient predicted produced receive retrospective cohort study SARS-CoV-2 SARS-CoV-2 detection seeking social determinant social determinants social determinants of health Spanish subset variables were used white [DOI] 10.1007/s10903-021-01320-6 PMC 바로가기 [Article Type] Article
A New Scoring Model to Diagnose COVID-19 Using Lung Ultrasound in the Emergency DepartmentResearch Published on 2022-02-012022-10-31 Journal: The Egyptian Journal of Bronchology [Category] COVID-19, [키워드] age consolidation Corona virus correlated COVID-19 COVID-19 infection COVID-19 patient Department diagnose died Ejection fraction Emergency Fever had more independent predictor initial lung Lung ultrasound Model negative test New New Score non-COVID-19 group Patient Pneumonia positive predictor Prognosis pulmonary congestion recruited Registered reported Result SARS-CoV-2 Scoring sensitivity significantly smoking specificity Ultrasound X-ray [DOI] 10.1186/s43168-021-00102-w PMC 바로가기 [Article Type] Research
T-cell immune response after mRNA SARS-CoV-2 vaccines is frequently detected also in the absence of seroconversion in patients with lymphoid malignanciesmRNA SARS-CoV-2 백신 후 T 세포 면역 반응은 림프 악성 종양 환자에서 혈청 전환이 없는 경우에도 자주 감지됩니다Clinical Trial Published on 2022-02-012022-09-12 Journal: British Journal of Haematology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] absence affected age and sex Analysis anti-cancer treatment anti-CD20 Anti-CD20 antibodies Anti-CD20 antibody anti-CD20 treatment antibody B-cell lymphoma cellular Chemotherapy treatment Complete conducted COVID-19 Diagnosis evaluated healthy subject Humoral response immune immune response Immunoglobulin increased mortality independent predictor lowest lymphoid lymphoid malignancies. lymphoma maintain malignancies malignancy Measures mRNA mRNA vaccination Multiple myeloma Patient Prospective Study Protective raise receiving Result SARS-CoV-2 vaccine Seroconversion seroconversion rate serological serological response seronegative patient subgroup of patient T-cell T-cell immune response T-cell Response Treatment vaccination [DOI] 10.1111/bjh.17877 PMC 바로가기 [Article Type] Clinical Trial
Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortalityCOVID-19에서 지속적으로 상승된 보체 대체 경로 바이오마커는 저산소혈증과 상관관계가 있으며 병원 내 사망률을 예측합니다Article Published on 2022-02-012022-09-11 Journal: Medical Microbiology and Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Activation Alternative pathway analyzed Biomarker C-reactive protein C5a cause complement Complement activation coronavirus disease Coronavirus disease 2019 correlations COVID-19 COVID-19 patient elevated enzyme enzyme-linked immunosorbent assays Evidence Factor Factor B ferritin healthy control healthy controls Hypoxemia ICU ICU admission IL-6 Immunity in-hospital mortality independent predictor Inflammatory response Innate Innate immunity lectin Level Lung disease marker measure Mortality Multi-organ damage overactivation pathway Patient patient sera predict prospectively studied quantified reduction Respiratory function risk SC5b-9 sera Serum level severely ill COVID-19 patients severity significantly sustained the patient [DOI] 10.1007/s00430-021-00725-2 PMC 바로가기 [Article Type] Article
Prognostic impact of toll-like receptors gene polymorphism on outcome of COVID-19 pneumonia: A case-control studyCOVID-19 폐렴의 결과에 대한 유료 유사 수용체 유전자 다형성의 예후 영향: 사례 대조 연구Article Published on 2022-02-012022-09-11 Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), SARS, 변종, [키워드] age allele allelic Analysis association case-control study controls COVID-19 COVID-19 pneumonia COVID-19 pneumonia patient Gene polymophism Genotype genotyped Host immune response increased risk independent predictor independent predictors Infection INR investigated involved LDH Logistic regression lymphocyte Male sex Mortality Multivariate analysis mutant outcome Pneumonia polymorphism Polymorphisms predictor Prognosis real time PCR Real-time PCR Risk factors SARS-COV-2 infection significantly SPO susceptibility TaqMan the disease TLR3 TLR7 TLR7 gene Toll-like receptor Toll-like receptor 3 Toll-like receptors viral infection viral infections [DOI] 10.1016/j.clim.2022.108929 PMC 바로가기 [Article Type] Article