Nutraceutical Strategies for Suppressing NLRP3 Inflammasome Activation: Pertinence to the Management of COVID-19 and BeyondNLRP3 Inflammasome 활성화를 억제하기 위한 기능식품 전략: COVID-19 및 그 이후의 관리에 대한 적합성Review Published on 2020-12-252022-09-12 Journal: Nutrients [Category] MERS, SARS, 진단, [키워드] Activation AMPK Atherosclerosis Autoimmune disorders berberine cell death Complication COVID-19 diabetes disorders ferulic acid functional glucosamine Gout Hydrogen sulfide Inflammasome inflammasomes Inflammatory interleukin-1β lipoic acid macular degeneration melatonin Molecular biology Myocardial infarction N-acetylcysteine neurological NLRP3 NLRP3 inflammasome nutraceutical pathogenic pathology phycocyanobilin priming promote protein complex proteolytic pyroptosis Strategy Stress Support Suppressing the cytokine storm utility variety Zinc [DOI] 10.3390/nu13010047 PMC 바로가기 [Article Type] Review
Additive Effects of Zinc Chloride on the Suppression of Hepatitis A Virus Replication by Interferon in Human Hepatoma Huh7 CellsArticle Published on 2020-11-012023-05-31 Journal: In vivo (Athens, Greece) [Category] A형 간염, Fulltext, [키워드] antivirals HAV inflammasomes interferon Zinc [DOI] 10.21873/invivo.12168 PMC 바로가기
Could Sars-Cov2 affect MS progression?Review Published on 2020-11-012023-07-12 Journal: Multiple sclerosis and related disorders [Category] SARS, [키워드] COVID-19 inflammasomes Long-term sequela microglia Sars-CoV2, Multiple sclerosis. [DOI] 10.1016/j.msard.2020.102540 PMC 바로가기 [Article Type] Review
4,4′-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor4,4′-다이아미노디페닐 설폰(DDS) 염증소체 경쟁자로서Article Published on 2020-08-192022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, 한센병, [키워드] 4,4′-diaminodiphenyl sulfone (dapsone) Activation AD Alter Alzheimer’s disease Alzheimer’s disease Antibiotics binding caspase-1 cause cleaved Cognitive impairment Combination DDS demonstrated diagnosed Diseases effective Effects Factor Fever fibrosis genetic polymorphisms Hansen’s disease human disease immune response implicated Inflammasome inflammasomes intracellular domain involved Korean lepromatous leprosy (also known as Hansen’s disease) leprosy ligands LL Lung inflammation MADDS mechanism microbial Mild molecular monoacetyldapsone MPO Mutation myeloperoxidase NACHT, LRR and PYD domains-containing protein 3 NLRP3 NLRP3 inflammasome Parkinson’s disease Patient protein 3 receptor Regulation reported responsible S protein SARS-CoV SARS-CoV-2 Sulfone susceptibility tested TLR TLR2 TLRs Toll-like receptor treated Treatment type 2 diabetes variety viruses zoonotic [DOI] 10.3390/ijms21175953 PMC 바로가기 [Article Type] Article
Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death인간 GBP1은 살모넬라와 톡소플라스마를 차별적으로 표적하여 미생물 리간드 인식과 카스파제 매개 세포 사멸을 허가합니다.Article Published on 2020-08-112024-08-21 Journal: Cell Reports [Category] 살모넬라증, [키워드] Apoptosis Caspases GBP1 inflammasomes pyroptosis Salmonella enterica Typhimurium Toxoplasma gondii
Tobacco, but Not Nicotine and Flavor-Less Electronic Cigarettes, Induces ACE2 and Immune DysregulationArticle Published on 2020-07-312022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] ACE2 ASC caused CCL20 CCL5 CCR1 cellular receptor chemokine COVID-19 COVID-19 infection COVID-19 pandemic CXCL1 CXCL2 CXCL8 Cytokine dysregulation Cytokine storm Cytokines dataset demonstrated dysregulation Electronic cigarettes Epidemics exacerbate Genes hallmark IL-1B immune response implicated independent Infection Inflammasome inflammasome activation inflammasomes Inflammation Nicotine NOD2 outcome overlap pathway pro-inflammatory cytokine Release risk RNA expression SARS-CoV-2 severe cases smoker Smokers smoking susceptibility the SARS-CoV-2 virus Tobacco upregulate upregulated upregulation vaping [DOI] 10.3390/ijms21155513 PMC 바로가기 [Article Type] Article
Novel therapeutic targets for SARS-CoV-2-induced acute lung injury: Targeting a potential IL-1β/neutrophil extracellular traps feedback loopArticle Published on 2020-05-302023-06-16 Journal: Medical Hypotheses [Category] MERS, SARS, [키워드] coronavirus COVID19 inflammasomes neutrophil extracellular traps (NETs) SARS [DOI] 10.1016/j.mehy.2020.109906 PMC 바로가기 [Article Type] Article
Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation시겔라 소네이 O-항원은 내부화, 액포 탈출 및 인플라마좀 활성화를 억제한다.Research Article Published on 2019-12-172024-07-30 Journal: mBio [Category] 세균성이질, [키워드] host-pathogen interactions inflammasomes macrophages O-antigen Shigella [DOI] 10.1128/mBio.02654-19 PMC 바로가기 [Article Type] Research Article
Tetramethylpyrazine supplementation reduced Salmonella Typhimurium load and inflammatory response in broilers테트라메틸피라진 보충이 육계에서 살모넬라 타이피무리움 부하와 염증 반응을 감소시켰다.Article Published on 2019-08-012024-08-21 Journal: Poultry Science [Category] 살모넬라증, [키워드] Broilers Cytokines inflammasomes salmonellosis tetramethylpyrazine.
Emerging Therapeutic Targets and Experimental Drugs for the Treatment of NAFLDReview Published on 2018-09-192023-08-30 Journal: Diseases [Category] E형 간염, [키워드] acetyl-coenzyme A carboxylase apoptosis signal-regulating kinase 1 chemokine receptor 2 and 5 drug therapy farnesoid X receptor Fibroblast growth factor 19 galectin-3 protein inflammasomes NAFLD NASH Nonalcoholic Fatty Liver Disease selective thyroid hormone receptor-beta toll-like receptor 4 [DOI] 10.3390/diseases6030083 PMC 바로가기 [Article Type] Review