Repurposing tetracyclines for acute respiratory distress syndrome (ARDS) and severe COVID-19: a critical discussion of recent publications급성 호흡 곤란 증후군(ARDS) 및 중증 COVID-19에 대한 테트라사이클린 용도 변경: 최근 간행물에 대한 비판적 논의Article Published on 2022-05-012022-09-11 Journal: Expert opinion on investigational drugs [Category] COVID19(2023년), SARS, 신약개발, [키워드] activities acute respiratory distress acute respiratory distress syndrome addition antibiotic antiviral activity approach ARDS Area benefit Combination COVID-19 COVID-19 pandemic COVID-19 patients Critical doxycycline Drug repurposing Effectiveness Efficacy Evidence expert fibrosis immunomodulatory incyclinide inflammatory reaction initial limitation limitations Minocycline overcome pharmacological repurposing respiratory distress Respiratory distress syndrome safety profile SARS-CoV2 scarcity scientific evidence severe COVID-19 shown syndrome Tetracycline tetracyclines therapeutic potential therapy [DOI] 10.1080/13543784.2022.2054325 PMC 바로가기 [Article Type] Article
Diagnostics and Treatments of COVID-19: A Living Systematic Review of Economic EvaluationsResearch article Published on 2022-05-012022-10-05 Journal: Value in health : the journal of the International [Category] 신약개발, 진단, 치료법, [키워드] Accuracy analyses Analysis approach approaches benefit cost-effectiveness COVID-19 COVID-19 pandemic COVID-19 test database Dexamethasone diagnostic test diagnostics disease severity Economic evaluation effective English estimate estimates evaluated Evidence Gray Health technology assessment Healthcare system Hospitalization hypothetical identify IMPROVE inclusion criteria limitations methodological objective offer pharmacological treatments Remdesivir Repository resolved respond Result review SARS-CoV-2 searched subject survival systematic review Treatment treatments for COVID-19 were excluded [DOI] 10.1016/j.jval.2022.01.001 [Article Type] Research article
Types and Applications of Nicking Enzyme-Combined Isothermal AmplificationNicking 효소 결합 등온 증폭의 유형 및 응용Review Published on 2022-04-212022-09-11 Journal: International Journal of Molecular Sciences [Category] 진단, 치료제, [키워드] amplification amplify application biochemical cleavage clinics Community complexity COVID-19 diagnostic diagnostics Disadvantages Efficiency enzyme Enzymes hospitals Immunodiagnosis IMPROVE Intensive isothermal isothermal amplification limitations molecular molecular detection Molecular diagnosis Nicking nicking enzyme. nucleic acid nucleic acids outbreak overcome platform POCT point-of-care Research shown subject target targets temperature Type [DOI] 10.3390/ijms23094620 PMC 바로가기 [Article Type] Review
Review of selected animal models for respiratory coronavirus infection and its application in drug researchReview Published on 2022-03-242022-10-04 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome Analysis animal animal model animal models Characteristics Clinical features Clinical signs coronavirus Coronavirus infection Disadvantages disease drug Efficacy evaluate ferrets function hamsters Histopathology include Infection information limitations management mechanism mice New Novel coronavirus Numerous pathogen Pathogenesis reported Research Respiratory Coronavirus review SARS‐CoV‐2 SARS‐CoV‐2 selected Strains susceptible therapeutic drug Transmission Vaccines Viral pneumonia viral replication virus virus replication Wuhan [DOI] 10.1002/jmv.27718 PMC 바로가기 [Article Type] Review
Fulminant and Non-fulminant Clinical COVID-19 Myocarditis in the New York City Area in 2020Observational Study Published on 2022-03-082022-10-05 Journal: Annals of Global Health [Category] 임상, [키워드] Area Atrial fibrillation Characteristics clinical Clinical course clinically complication of COVID-19 Coronary artery disease COVID-19 cross-sectional D-dimer defined Diagnosis echocardiographic Elevation Exploratory analysis ferritin fulminant generate geometric hypothese increasingly Inflammatory marker Isolation Laboratory Laboratory testing limitations Logistic regression MRI myocarditis New York City offer Patient patients precautions presenting symptoms required resource severity severity of COVID-19 significantly higher stratified Student T-test supplemental oxygen systemic inflammation to define ventricular while [DOI] 10.5334/aogh.3583 PMC 바로가기 [Article Type] Observational Study
COVID-19 disease diagnosis from paper-based ECG trace image data using a novel convolutional neural network model새로운 컨볼루션 신경망 모델을 사용하여 종이 기반 ECG 추적 이미지 데이터에서 COVID-19 질병 진단Article Published on 2022-03-012022-09-11 Journal: Physical and engineering sciences in medicine [Category] SARS, 치료기술, [키워드] Abnormalities abnormality Accuracy addition alternative method alternative methods AUC value binary classification cardiovascular cardiovascular diseases Cardiovascular diseases diagnosis cardiovascular system caused clinical clinician Convolutional neural network Convolutional neural networks COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 infected patient COVID-19 infected patients COVID-19 pandemic COVID-19 patients COVID-19 virus deep deep learning detect Diagnosis diagnosis of COVID-19 Diagnostic method disease ECG Electrocardiography heartbeat Impact infected patients limitations machine machine learning Medical imaging multi-classification Myocardial Myocardial infarction network model Neural normal pandemic PCR tests Respiratory system RT-PCR test shown Treatment treatment of COVID-19 patients [DOI] 10.1007/s13246-022-01102-w PMC 바로가기 [Article Type] Article
ECG-BiCoNet: An ECG-based pipeline for COVID-19 diagnosis using Bi-Layers of deep features integrationECG-BiCoNet: 심층 기능 통합의 이중 레이어를 사용하여 COVID-19 진단을 위한 ECG 기반 파이프라인Article Published on 2022-03-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 치료기술, [키워드] Accuracy alleviate approach benefit categories clinician Convolutional neural network Convolutional neural networks (CNN) COVID-19 COVID-19 diagnosis deep deep learning diagnose diagnosing Diagnosis Discrete Discrete wavelet transform (DWT) ECG ECG trace Image. electrocardiogram feature Features FIVE fused Health help Image IMPROVE investigated limitation limitations lockdown machine learning classifiers organizations overcome several limitations Taking virus wavelet transform [DOI] 10.1016/j.compbiomed.2022.105210 PMC 바로가기 [Article Type] Article
Sustained Impairment in Cardiopulmonary Exercise Capacity Testing in Patients after COVID-19: A Single Center ExperienceCOVID-19 이후 환자의 심폐 운동 능력 테스트에서 지속적인 손상: 단일 센터 경험Research Article Published on 2022-03-012022-09-10 Journal: Canadian Respiratory Journal [Category] MERS, SARS, 진단, 치료기술, [키워드] acute COVID-19 Capacity cardiopulmonary exercise testing center Chronic fatigue comparable correlated COVID-19 COVID-19 infection described Deterioration Ejection fraction evaluate exercise Exercise capacity Exercise limitation experience female patient Follow-up Gas exchange Improvements Infection initial limitation limitations Limited magnetic resonance imaging male MRI objective offered oxygen pathologic Patient patients performed pulse reduced Result severity of COVID-19 Stress Symptom syndrome Testing Vascular ventilatory was related [DOI] 10.1155/2022/2466789 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 genome quantification in wastewaters at regional and city scale allows precise monitoring of the whole outbreaks dynamics and variants spreading in the population지역 및 도시 규모의 폐수에서 SARS-CoV-2 게놈 정량화를 통해 인구에 확산되는 전체 발병 역학 및 변이체를 정밀하게 모니터링할 수 있습니다.Article Published on 2022-03-012022-09-11 Journal: The Science of the total environment [Category] SARS, 변종, [키워드] approach Asymptomatic average B.1.1.7 cause Cluster collected coronavirus correlation country COVID-19 COVID-19 outbreak decision Deletion Epidemiology FIVE France Genome greater Health health monitoring Health status help highlight implementation incidence incidence rates individual Infection inhalation Lead time limitations Local measure observé outbreak overcome pandemic Paris Patient performed plant predominant proportion quantification Quantitative analysis respiratory droplet Respiratory droplets RT-qPCR SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 transmission selection pressure sensitivity severe complications sewer Spike protein Stool the spike protein today Treatment variant Variant monitoring variants variants of concern virus transmission VoC wastewater [DOI] 10.1016/j.scitotenv.2021.152213 PMC 바로가기 [Article Type] Article
First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and WalesResearch Article Published on 2022-02-222022-10-29 Journal: PLoS Medicine [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 95% CI 95% confidence interval addition administration Analysis association assumption average baseline benefit Blood BNT162b2 Brain carried Case report case sery caused ChAdOx1 clinically Cohort combined cohort conditions Control count country COVID-19 COVID-19 vaccination dataset datasets dose doses elevated England estimates event events Evidence examined expected extreme first dose Follow-up group Health Health authority incidence rate increased risk independent indication individual information initial limitations Mortality National observation observation period of BNT162b2 Older age outcome outcome measure person year person years Pfizer-BioNTech platform Poisson model primary care Public quantification recorded required researcher risk secondary care Serious Adverse Event Study design thrombosis Topic United Kingdom vaccination Vaccine variable venous Virological with COVID-19 [DOI] 10.1371/journal.pmed.1003927 PMC 바로가기 [Article Type] Research Article