mechanically ventilated patient – Page 4 – Communicable Diseases Research

Soliris to Stop Immune-Mediated Death in COVID-19 (SOLID-C19)—A Compassionate-Use Study of Terminal Complement Blockade in Critically Ill Patients with COVID-19-Related Adult Respiratory Distress Syndrome

COVID-19 (SOLID-C19)에서 면역 매개 사망을 중단하는 Soliris-COVID-19 관련 성인 호흡기 고통 증후군을 앓고있는 중증 환자의 말기 보완 봉쇄에 대한 자비로운 사용 연구.

Article

Published on 2021-12-032022-08-31
Journal: Viruses [Category] SARS, 신약개발, 진단,

Continuous long-term wireless measurement of right ventricular pressures and estimated diastolic pulmonary artery pressure in patients with severe COVID-19 acute respiratory distress syndrome

중증 COVID-19 급성 호흡곤란 증후군 환자의 우심실압 및 확장기 폐동맥압 추정치를 장기간 무선으로 지속적으로 측정

Article

Published on 2021-12-012022-09-11
Journal: ESC heart failure [Category] SARS, 치료기술,

[키워드] acute respiratory distress acute respiratory distress syndrome amplitude ARDS Continuous Course COVID-19 detect diastolic disease ePAD. evaluated heart failure hypertension Iloprost Indicator Inhaled insertion left heart failure mechanically ventilated patient mechanically ventilated patients mmHg Mortality nitric oxide non-survivor Non-survivors outcome Patient percentile PPM probe pulmonary pulmonary artery pulmonary artery pressure pulmonary hypertension respiratory distress Respiratory distress syndrome Right ventricular right ventricular pressure severe COVID-19 significant decrease significantly higher significantly lower Sildenafil surviving patients survivor syndrome systolic pressure the patient treat two groups variable Ventilated ventricular Ventricular pressure
[DOI] 10.1002/ehf2.13600 PMC 바로가기 [Article Type] Article

Clinical outcomes of intravenous immunoglobulin therapy in COVID-19 related acute respiratory distress syndrome: a retrospective cohort study

COVID-19 관련 급성 호흡기 병원 증후군에서 정맥 내 면역 글로불린 요법의 임상 결과 : 후 향적 코호트 연구

Research

Published on 2021-11-082022-09-01
Journal: BMC Pulmonary Medicine [Category] Fulltext, MERS, 진단,

[키워드] 95% CI Acute kidney injury acute respiratory distress acute respiratory distress syndrome addition adjust AKI Analysis ARDS clinical Cohort conducted confounders coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Electronic health record Electronic health records General Hospital groups ICU ICU mortality ICUs Immunoglobulin immunoglobulin therapy immunomodulatory therapy incidence intensive care unit intensive care units Intravenous immunoglobulin Invasive mechanical ventilation IVIG mechanical ventilation mechanically ventilated mechanically ventilated patient mechanically ventilated patients Mortality observation outcome Patient Primary outcome Propensity score propensity score matching randomized clinical trial receiving respiratory distress Respiratory distress syndrome Result Retrospective analysis retrospective cohort study routine care secondary Secondary outcomes significantly higher statistically significant difference study population supplementary material survival survival analysis syndrome systemic inflammation therapy two group two groups ventilator-free day Ventilator-free days was used with COVID-19
[DOI] 10.1186/s12890-021-01717-x PMC 바로가기 [Article Type] Research

COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning

Review

Published on 2021-10-282022-10-30
Journal: Journal of Personalized Medicine [Category] COVID-19,

Long-term survival of mechanically ventilated patients with severe COVID-19: an observational cohort study

Research

Published on 2021-10-022022-10-28
Journal: Annals of Intensive Care [Category] COVID-19,

[키워드] 95% CI acute respiratory syndrome administration age ARDS cohort study coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroid COVID-19 develop diabete digestive dosage Factor help Hospital admission Hospital stay hypoxemic ICU ICU admission in-hospital mortality Infection intensive care unit intubation Invasive mechanical ventilation invasive ventilation long-term survival lymphocyte male mechanically ventilated patient median age Methylprednisolone Mortality multicentre nasopharyngeal sample National neutrophil noninvasive noninvasive respiratory Noninvasive ventilation Observational cohort study outcome participant Patient patients with COVID-19 Pneumonia polymerase chain positive positive pressure ventilation potential treatments Predictive Primary outcome Probability Ratio real time Registered Respiratory failure Result risk stratification SARS-CoV-2 secondary selective severe COVID-19 Spain supplementary material Support survival survival rate
[DOI] 10.1186/s13613-021-00929-y PMC 바로가기 [Article Type] Research

Increased Autotaxin Levels in Severe COVID-19, Correlating with IL-6 Levels, Endothelial Dysfunction Biomarkers, and Impaired Functions of Dendritic Cells

중증 코로나19에서 증가된 오토탁신 수치, IL-6 수치, 내피 기능 장애 바이오마커 및 수지상 세포 기능 손상과 상관관계

Article

Published on 2021-09-162022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 바이오마커, 진단, 치료기술, 치료제,

[키워드] ARDS Autotaxin autotaxin (ATX; ENPP2) Biomarkers cohorts correlated COVID-19 COVID-19 pathogenesis COVID-19 patients Cytokine storm dataset dendritic cells dendritic cells (DCs) Dexamethasone endothelial damage ENPP2 expression Extracellular fibrosis function functional homeostasis Hospitalization hyperinflammation IL-6 Immune cell immune cells Impaired include Increased independent Inflammation Level LPA lysophosphatidic acid (LPA) mechanically ventilated mechanically ventilated patient mechanically ventilated patients mRNA level multifunctional Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples pathologic pharmacological pleiotropic pulmonary fibrosis pulmonary injury reduced RNA sequencing scale analysis secreted Serum level severe COVID-19 patients shown Signaling Single Cell suggested suppression Therapeutic benefit therapeutic benefits therapeutic option Treatment vascular dysfunction
[DOI] 10.3390/ijms221810006 PMC 바로가기 [Article Type] Article

Timing of corticosteroids impacts mortality in hospitalized COVID-19 patients

Observational Study

Published on 2021-09-012022-10-04
Journal: Internal and Emergency Medicine [Category] 임상,

[키워드] 95% CI absence Admission Analysis analyzed benefit collected coronavirus Corticosteroid corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 COVID-19 patients death demographic evaluated first dose group Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Impact in-hospital mortality initial initiated Invasive mechanical ventilation Laboratory lower risk mechanically ventilated patient Mortality multivariable Oxygen therapy Patient patients receiving oxygen quantified receiving reduced risk Regression analyses requiring supplemental oxygen symptom onset the patient the timing therapy time time interval Timing Treatment variable was related
[DOI] 10.1007/s11739-021-02655-6 PMC 바로가기 [Article Type] Observational Study

Dynamics of SARS-CoV2 Infection and Multi-Drug Resistant Bacteria Superinfection in Patients With Assisted Mechanical Ventilation

SARS-COV2 감염의 역학 및 기계적 환기가 보조 된 환자에서 SARS-COV2 감염 및 다 약성 내성 박테리아 초부 감염

Cellular and Infection Microbiology

Published on 2021-08-122022-08-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단, 치료기술, 치료제,

[키워드] 2019-nCoV assay antimicrobial resistance Bacteria Bacterial bacterial and fungal infections bacterial superinfection bronchial aspirate samples carbapenem carbapenems carried CFU characterisation colonisation colony forming units COVID-19 COVID-19 disease COVID-19 patients Culture Deletion demonstrated detection dithiothreitol Dynamics Evolution fungal Fungal infection fungi growth Health hospitalisation ICU incidence intensive care intensive care unit isolate Klebsiella pneumoniae Mechanical mechanically ventilated patient mechanically ventilated patients molecular analysis Mutation objective outcome pathogen Patient patients pneumoniae Prospective Study Pseudomonas aeruginosa Resistant Result room temperature SARS-CoV-2 SARS-CoV-2-infected patient SARS-CoV2 severe COVID-19 disease severe SARS specimen Strains superinfection temperature These data treated was performed
[DOI] 10.3389/fcimb.2021.683409 PMC 바로가기 [Article Type] Cellular and Infection Microbiology

Characterization of Secondary Bacterial Infections and Antibiotic Use in Mechanically Ventilated Patients With COVID-19 Induced Acute Respiratory Distress Syndrome

Original Research

Published on 2021-08-102022-10-29
Journal: Journal of Intensive Care Medicine [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory distress antibiotic antibiotic use Antibiotics ARDS Bacteremia Bacterial Bacterial sepsis bacterial species characterization COVID-19 Culture heterogeneous high risk hospital Hospital stay Hospitalization incidence induced Infection mechanical ventilation mechanically ventilated patient Mortality Nosocomial infections Patient patients patients with COVID-19 per day Pneumonia populations respiratory retrospective cohort study Seattle secondary secondary bacterial infection Staphylococcus aureus study period syndrome urinary tract infection UTI ventilated patient Washington with COVID-19
[DOI] 10.1177/08850666211021745 PMC 바로가기 [Article Type] Original Research

High sedation needs of critically ill COVID-19 ARDS patients—A monocentric observational study

Research Article

Published on 2021-07-272022-10-28
Journal: PLoS ONE [Category] COVID-19,

[키워드] 2019 coronavirus disease acute respiratory distress Affect affected age Analgesia Analysis ARDS association Combination coronavirus COVID-19 COVID-19 patient Critical care Critically ill Critically ill patient Data analysis demographic data dosage dosages dose ECMO global pandemic infused intensive care intubated patient intubation Logistic regression majority mechanically ventilated mechanically ventilated patient observation Patient performed prone positioning recorded regimen required Respiratory failure Result retrospective Sedation syndrome therapy Treatment Ventilation was used with COVID-19
[DOI] 10.1371/journal.pone.0253778 PMC 바로가기 [Article Type] Research Article