1 H, 13 C and 15 N chemical shift assignment of the stem-loop 5a from the 5′-UTR of SARS-CoV-2Article Published on 2021-01-232022-10-27 Journal: Biomolecular Nmr Assignments [Category] Coronavirus, COVID-19, SARS, [키워드] 5′-UTR 5′-untranslated region 5′-UTR Affect antiviral drug asymmetric conserved COVID-19 pandemic COVID19-NMR element feature Genome Major NMR spectroscopy nucleotide positive Replication RNA RNA genome SARS-CoV-2 sequence single-stranded SL5a Solution NMR spectroscopy supplementary material targets translation viral replication virus [DOI] 10.1007/s12104-021-10007-w PMC 바로가기 [Article Type] Article
NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating CytokinesArticle Published on 2021-01-112023-06-15 Journal: Journal of Proteome Research [Category] MERS, [키워드] Biomarkers COVID-19 diagnostic modeling IVDr Lipoproteins metabolic phenotyping NMR spectroscopy plasma SARS-CoV-2 single-pulse spin-echo [DOI] 10.1021/acs.jproteome.0c00876 PMC 바로가기 [Article Type] Article
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoproteinSARS-CoV-2 뉴클레오캡시드 인단백질에 의한 RNA 인식의 구조적 기초Research Article Published on 2020-12-022022-08-13 Journal: PLoS Pathogens [Category] Medicine and Health Sciences, MERS, SARS, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis antiviral strategy arginine atomic atomic models Author bind binding binding site C-terminal causative agent characterized complex coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease dimeric domain double-stranded RNA ENCODE envelope full length Genome Interaction intrinsically involved Like lysines membrane N protein N proteins N-terminal N-terminal domain new SARS-CoV-2 NMR NMR spectroscopy nonstructural proteins nucleocapsid other coronaviruses pandemic Proteins provided respiratory ribonucleoprotein RNA RNA genome RNA virus SARS-CoV-2 SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 single-stranded single-stranded positive-sense spike structural protein structural proteins subsequent supported the N protein the SARS-CoV-2 the SARS-CoV-2 virus Viral viral genome viral membrane virion virion assembly [DOI] 10.1371/journal.ppat.1009100 PMC 바로가기 [Article Type] Research Article
Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 InfectionArticle Published on 2020-11-062023-07-12 Journal: Journal of Proteome Research [Category] SARS, [키워드] amino acids Biomarkers COVID-19 Lipoproteins mass spectrometry metabolic phenotyping mosaic disease Multiorgan damage NMR spectroscopy SARS-CoV-2 systems model. [DOI] 10.1021/acs.jproteome.0c00519 PMC 바로가기
Structural Characterization of N‐Linked Glycans in the Receptor Binding Domain of the SARS‐CoV‐2 Spike Protein and their Interactions with Human LectinsResearch Article Published on 2020-10-222022-10-28 Journal: Angewandte Chemie (International ed. in English) [Category] COVID-19, SARS, [키워드] 3D model affected analysed analyses Analysis characterization characterized complexes epitope evaluated Evidence experiment expressed glycan glycoprotein HEK293F cell Human identify infection process Interaction lectin molecular recognition NMR NMR spectroscopy organ Perspective Receptor binding domain reported responsible SARS-CoV2 SARS‐CoV‐2 SARS‐CoV‐2 spike SARS‑CoV2 spike glycoprotein Structure the RBD tissue [DOI] 10.1002/anie.202011015 PMC 바로가기 [Article Type] Research Article
Signal amplification by reversible exchange for COVID-19 antiviral drug candidatesArticle Published on 2020-08-312022-10-04 Journal: Scientific Reports [Category] MERS, 치료법, 치료제, [키워드] amplification Analytical chemistry antiviral drug candidate carried Clinical treatment Coronavirus pneumonia COVID-19 dependent on Diagnosis disease drug drug candidate Favipiravir feature Hydroxychloroquine labeling Medical and clinical diagnostics molecular NMR spectroscopy nuclear nuclei Perspective Research signal structures tested therapeutic transfer Treatment Trial [DOI] 10.1038/s41598-020-71282-6 PMC 바로가기 [Article Type] Article
Atlas of coronavirus replicase structureArticle Published on 2013-12-162022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Atla bioinformatics coronavirus Coverage Cryoelectron microscopy functional in viral International Microscopy NMR NMR spectroscopy nonstructural protein Pathogenesis produced Protein protein structure Proteins Replication SARS Coronavirus SARS-CoV Small angle X-ray scattering Structure structures variety X-ray crystallography X-ray scattering [DOI] 10.1016/j.virusres.2013.12.004 PMC 바로가기 [Article Type] Article
New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities †Article Published on 2011-09-262022-10-30 Journal: Marine Drugs [Category] Coronavirus, [키워드] activity Analysis anti-trypanosomal antiparasitic assigned Axinella cathepsin B cathepsin L Compound cysteine protease derivative derivatives Leishmania major marine sponge New NMR spectroscopy protease protease inhibition SARS-CoV M Streptomyce Streptomyces axinellae Structure tested tetromycin Trypanosoma [DOI] 10.3390/md9101682 PMC 바로가기 [Article Type] Article