pulmonary inflammation – Page 4 – Communicable Diseases Research

Efficacy and safety of umbilical cord mesenchymal stem cells for the treatment of patients with COVID-19

Research article

Published on 2021-05-112022-10-05
Journal: Clinics [Category] SARS, 바이오마커, 치료법,

Vaping Exacerbates Coronavirus-Related Pulmonary Infection in a Murine Model

Physiology

Published on 2021-05-102022-10-31
Journal: Frontiers in Physiology [Category] COVID-19,

[키워드] beta coronavirus Contact Control coronavirus coronavirus disease Coronavirus infection COVID-19 cytokine Cytokines death described develop disease disease severity dysregulation E-cigarette Evidence exacerbate Fever global pandemic Histopathology indicate Infectious disease Inflammation intranasal less lung means measure MHV-A59 mice Mild Model Mortality outbreak pathology pulmonary pulmonary disease pulmonary inflammation Respiratory disease respiratory droplet risk factor SARS-CoV-2 Severe respiratory distress severity smoking spirometry suffered syndrome the SARS-CoV-2 therapeutic intervention Toxicity transmitted while WHO World Health Organization
[DOI] 10.3389/fphys.2021.634839 PMC 바로가기 [Article Type] Physiology

Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

Article

Published on 2021-05-042023-06-15
Journal: Immunity [Category] MERS, SARS,

[키워드] β-catenin Alveolar macrophages HIF-1α Influenza virus pulmonary inflammation SARS-CoV-2 Self-renewal tissue macrophages tissue repair
[DOI] 10.1016/j.immuni.2021.04.001 PMC 바로가기 [Article Type] Article

The role of chest CT quantitative pulmonary inflammatory index in the evaluation of the course and treatment outcome of COVID-19 pneumonia

Article

Published on 2021-04-082022-10-04
Journal: Scientific Reports [Category] MERS, SARS, 치료법,

[키워드] Admission age analyzed assessment assist average body temperature C-reactive protein (CRP can be used Chest Chest CT clinical symptom Complete consolidation correlated correlation Course COVID-19 CRP death decrease diagnosed discharge discharged Diseases erythrocyte sedimentation rate ESR female Fever Ground glass opacity help Hospital stay Hospitalization increase in Inflammatory inflammatory change involved Laboratory lactate dehydrogenase LDH left lower lobe lesion linear lung lung lobe Lungs lymphocyte male manifestation median Medical research MONITOR Patient patients patients died patients with COVID-19 Pneumonia positively correlated pulmonary inflammation Quantitative remained residual right lower lobe RT-PCR severity significantly Signs and symptoms small vessel the median the patient Treatment Treatment outcome White blood cell
[DOI] 10.1038/s41598-021-87430-5 PMC 바로가기 [Article Type] Article

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

COVID-19 발병의 전염증성 사이토카인: 무엇이 잘못되었습니까?

Review

Published on 2021-04-012022-09-12
Journal: Microbial pathogenesis [Category] MERS, SARS, 유전자 메커니즘, 진단,

[키워드] addition appear cause caused China Clinical outcome contribute coronavirus 2 coronavirus disease country COVID-19 CRS cytokine Cytokine release syndrome Cytokines described effector cell exacerbated extensive lung damage human SARS-CoV-2 IL-17 IL-1β IL-6 IL-8 immune immune response immune system immunological infected with SARS-CoV-2 Infection Inflammation involved knowledge MERS non-immune outbreak Pathogenesis pro-inflammatory cytokine pro-inflammatory cytokines pulmonary inflammation respiratory SARS-CoV-2 Severe case severe COVID-19 patients spread to subject systemic inflammatory response thrombosis TNFα
[DOI] 10.1016/j.micpath.2021.104799 PMC 바로가기 [Article Type] Review

Influence of obesity on serum levels of SARS-CoV-2-specific antibodies in COVID-19 patients

COVID-19 환자의 SARS-CoV-2 특이 항체의 혈청 수준에 대한 비만의 영향

Research Article

Published on 2021-03-242022-08-13
Journal: PLoS ONE [Category] Biochemistry, SARS, 바이오마커, 진단,

[키워드] (C-reactive protein) (nonesterified fatty acids) acute respiratory syndrome amyloid A antibody Blood BMI Body body mass body mass index C-reactive protein chronic systemic inflammation condition Corona coronavirus coronavirus disease COVID-19 COVID-19 obese patient COVID-19 obese patients COVID-19 patient COVID-19 patients CRP evaluated exacerbated expected ferritin help Humoral immunity Hypothesis identify IgG antibodies immune dysfunction Immunity IMPROVE index individual inflammaging Inflammatory inflammatory conditions inflammatory markers Inflammatory response influence marker mass NEFA nonesterified fatty acids obese obese patients obesity Predictive Predictive value pro-inflammatory Protein pulmonary inflammation reduced respiratory Result risk SAA SARS-CoV-2 SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody SARS-CoV-2-specific antibody SARS-CoV-2-specific IgG secretion serum amyloid serum amyloid A protein Serum level serum levels Severe Acute Respiratory Syndrome Corona Virus Severe acute respiratory syndrome corona virus-2 shown specific IgG antibodies systemic inflammation
[DOI] 10.1371/journal.pone.0245424 PMC 바로가기 [Article Type] Research Article

The characteristics and evolution of pulmonary fibrosis in COVID-19 patients as assessed by AI-assisted chest HRCT

AI 지원 흉부 HRCT로 평가한 COVID-19 환자의 폐 섬유증의 특성 및 진화

Research Article

Published on 2021-03-232022-08-13
Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS,

[키워드] affected albumin bronchiectasis Characteristics Chest chest HRCT Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical discharge Evolution fibrosis Ground-glass opacities High-resolution HRCT IL-6 incidence independent risk factor independent risk factors interlobular septal thickening linear Mild moderate Moderate COVID-19 Most patients Patient patients patients with moderate proportion pulmonary fibrosis pulmonary inflammation resolved reticulation risk factor Risk factors significant difference significant differences significantly significantly higher was used
[DOI] 10.1371/journal.pone.0248957 PMC 바로가기 [Article Type] Research Article

Treatment of pulmonary fibrosis in one convalescent patient with corona virus disease 2019 by oral traditional Chinese medicine decoction: A case report

2019년 코로나 바이러스 질병으로 회복 중인 환자 1명의 폐 섬유증을 경구 한약 탕으로 치료: 증례 보고

Case Reports

Published on 2021-03-012022-08-31
Journal: Journal of integrative medicine [Category] MERS, SARS, 치료제,

Title of article: Mucosal-associated invariant T cells in lung diseases

Review

Published on 2021-02-262022-11-01
Journal: International immunopharmacology [Category] COVID-19, SARS,

[키워드] 5-OE-RU, 5-(2-oxoethylideneamino)-5-dribitylaminouracil 5-OP-RU, 5-(2-oxopropylideneamino)-5-dribitylaminouracil 6-FP, 6 formylpterin activated adaptive AHR, airway hyper responsiveness APC, antigen presenting cell Asthma BALF, bronchoalveolar lavage fluid CAP, Community-acquired pneumonia CCR, CC receptor CD, cluster of differentiation Cell CF, cystic fibrosis chronic obstructive COPD, Chronic obstructive pulmonary disease COVID-19 COVID-19, Coronavirus disease 2019 CXCR, chemokine CXC receptor cytokine receptor Disease progression DN, double negative dynamic balance Effects Evidence FEV1, forced expiratory volume in the first second GM-CSF, granulocyte–macrophage colony-stimulating factor Gzm, granzyme HIF-1α, hypoxia-inducible factor-1α HLA-DR, human leukocyte antigen DR IFN-γ, interferon-γ IL, interleukin IL4I1, interleukin-4-induced gene 1 ILCs, innate lymphoid cells Immune cell immune response Immunity Immunopathogenesis Infection Inflammation Injury iNKT, invariant natural killer T involved lung lung cancer Lung disease Lung diseases Lungs maintain MAIT, Mucosal-associated invariant T marker MHC, major histocompatibility complex microbial infection MR1, MHC-related protein 1 Mucosa-associated invariant T cells murine Pathogenesis PD-1, programmed cell death protein 1 PLZF, promyelocytic leukemia zinc finger Pneumonia potential therapeutic target Protective pulmonary disease pulmonary inflammation pulmonary tuberculosis respiratory epithelium RORγt, retinoic-acid-related orphan receptor γt SARS-CoV-2 shown SLE, systemic lupus erythematosus STAT3, signal transducer and activator of transcription 3 subset T cell T cell receptor T cells TB, Tuberculosis TCF7, transcription factor 7 TCR, T cell receptor Th, T helper these cell title TLR, Toll-like receptor TNF-α, tumor necrosis factor-α Treatment
[DOI] 10.1016/j.intimp.2021.107485 PMC 바로가기 [Article Type] Review

Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection

SARS-CoV-2 감염의 햄스터 모델에서 메틸프레드니솔론과 렘데시비르 조합의 유익한 효과

Coronaviruses

Published on 2021-02-252022-09-10
Journal: Emerging Microbes & Infections [Category] SARS, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Anti-inflammatory Antibody Response antibody response against Antiviral antiviral therapy benefit body weight Body weight loss boost caused clinical trials Combination combination therapy coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroid COVID-19 Cytokines Dexamethasone effective Efficacy expression glucocorticoid Glucocorticoids group hospitalized patients human monocyte-derived macrophages Inflammation macrophages Methylprednisolone monotherapy nasal Prevent prevented Proinflammatory cytokine proinflammatory cytokines pulmonary inflammation Randomized Receptor-binding domain Remdesivir replication of SARS-CoV-2 respiratory RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus shown Spike protein Support suppressed survival the receptor-binding domain Treatment Viral Viral load viral loads Viral protein weight loss
[DOI] 10.1080/22221751.2021.1885998 PMC 바로가기 [Article Type] Coronaviruses