A Recombinant Newcastle Disease Virus (NDV) Expressing S Protein of Infectious Bronchitis Virus (IBV) Protects Chickens against IBV and NDVArticle Published on 2018-08-102022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] Antigen bronchitis cause chicken Complete contagious contribute develop disease effective elicited expressing expressing S protein genetic engineering genetics IBV immunization immunoblotting Live attenuated vaccines Mutation neutralizing antibody outcome Protective provided recombinant Recombination reproductive resulting S protein S2 protein Safe SPF the disease the S protein Vaccine vaccine candidate vaccine strain variant virulent virus viruses [DOI] 10.1038/s41598-018-30356-2 PMC 바로가기 [Article Type] Article
Display of Porcine Epidemic Diarrhea Virus Spike Protein on Baculovirus to Improve Immunogenicity and Protective EfficacyArticle Published on 2018-06-272022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Asia baculovirus baculovirus display system Clinical signs clinical symptom complex control group control groups demonstrated disease display displaying effective elicited epidemic diarrhea exhibited experiment fecal full-length S protein generate Genotype IgG immune response immunization immunized immunogen immunogenicity Infection Intramuscular injection killing less mice Mild mimicking Modification Neonatal neutralizing antibody North America PEDV Protein robust Safe significantly significantly higher spike spike vaccine Taiwan the S1 protein vaccine candidate variant viral shedding virulent virus [DOI] 10.3390/v10070346 PMC 바로가기 [Article Type] Article
In silico design of a novel chimeric shigella IpaB fused to C terminal of clostridium perfringens enterotoxin as a vaccine candidate신규 키메라 시겔라 IpaB를 클로스트리디움 퍼프린젠스 엔테로톡신의 C 말단에 융합한 백신 후보의 인 실리코 설계Article Published on 2018-01-012024-08-22 Journal: Bioengineered [Category] 세균성이질, [키워드] Chimeric protein CPE IpaB Shigella vaccine candidate
Chimpanzee adenoviral vectors as vaccines for outbreak pathogensResearch Papers Published on 2017-12-302022-10-31 Journal: Human vaccines & immunotherapeutics [Category] Coronavirus, [키워드] adenoviral vector all age groups approach caused cellular Chimpanzee develop disease Drivers Ebola Epidemics Humoral immunity induce Infectious disease Lassa fever MERS MERS Co-V Nipah outbreak pathogen Pathogens platform pre-existing immunity Prostate cancer Safe Vaccine vaccine candidate Vaccines vector vectors Viral vector viral vectors West work [DOI] 10.1080/21645515.2017.1383575 PMC 바로가기 [Article Type] Research Papers
Association of antibodies to Plasmodium falciparum merozoite surface protein-4 with protection against clinical malariaArticle Published on 2017-12-042024-08-27 Journal: Vaccine [Category] 말라리아, [키워드] antibody Antibody-dependent respiratory burst Clinical protection Merozoite surface protein 4 P. falciparum vaccine candidate [DOI] 10.1016/j.vaccine.2017.10.012
Characterization of Pb51 in Plasmodium berghei as a malaria vaccine candidate targeting both asexual erythrocytic proliferation and transmissionPlasmodium berghei에서 Pb51의 특성화: 무성 적혈구 증식과 전파를 모두 겨냥한 말라리아 백신 후보Research Published on 2017-11-132024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] Asexual blood stage Pb51 Plasmodium berghei sexual stage transmission-blocking vaccine candidate [DOI] 10.1186/s12936-017-2107-2 PMC 바로가기 [Article Type] Research
A Large Size Chimeric Highly Immunogenic Peptide Presents Multistage Plasmodium Antigens as a Vaccine Candidate System against Malaria대형 크리미릭 고면역원성 펩타이드가 말라리아에 대한 백신 후보 시스템으로 다단계 말라리아 원충 항원을 제시합니다.Article Published on 2017-11-012024-08-12 Journal: Molecules [Category] 말라리아, [키워드] chimeric immunogen macromolecule synthesis malaria Plasmodium vaccine candidate [DOI] 10.3390/molecules22111837 PMC 바로가기 [Article Type] Article
Parainfluenza Virus 5 Expressing Wild-Type or Prefusion Respiratory Syncytial Virus (RSV) Fusion Protein Protects Mice and Cotton Rats from RSV ChallengeArticle Published on 2017-09-122022-10-06 Journal: Journal of Virology [Category] 진단, [키워드] Administered antibody Antigen backbone BALB/c mice candidate Cell-mediated immunity challenge characterized cotton demonstrated develop Efficacy Express expressing fusion fusion protein group Health hospitalizations Human humoral hydrophobic Immunity immunocompromised individuals immunogenic IMPROVE induce Infants Infection insertion intranasal intranasal route intranasally Lower respiratory tract lung mice Modification modifications MOST murine mutant nasal nasal congestion Neutralizing Neutralizing activity Neutralizing antibody titer parainfluenza virus pediatric PIV5 postfusion prefusion prefusion conformation Protective RAT reduced reducing Research respiratory respiratory syncytial virus respiratory tracts robust RSV severe complication shown Subcutaneous subcutaneously tested vaccination Vaccine vaccine candidate Viral load wild-type [DOI] 10.1128/JVI.00560-17 PMC 바로가기 [Article Type] Article
Isolation and Characterization of Vaccine Candidate Genes Including CSP and MSP1 in Plasmodium yoeliiarticle Published on 2017-06-302024-09-01 Journal: The Korean Journal of Parasitology [Category] 말라리아, [키워드] CSP DBP msp1 Plasmodium yoelii protective immunity rodent malaria model vaccine candidate [Article Type] article
A Single-Dose Recombinant Parainfluenza Virus 5-Vectored Vaccine Expressing Respiratory Syncytial Virus (RSV) F or G Protein Protected Cotton Rats and African Green Monkeys from RSV ChallengeArticle Published on 2017-05-122022-10-06 Journal: Journal of Virology [Category] 진단, [키워드] African African green monkey African green monkeys animal model Antibody Response Antibody titer boost challenge Clinical symptoms Complete cotton dose Efficacy elicited evaluated expressing glycoprotein green Human Immunity immunization immunized immunocompromised individuals indicated Infants Infection intranasal less Lower respiratory tract Lung pathology Lung protection Monkey mucosal neutralization neutralization titer parainfluenza virus pediatric PIV5 vectors platform Population produced PROTECT Protective Protein provided RAT recombinant Replication respiratory respiratory syncytial virus RSV Safe serum serum antibody severe respiratory disease single dose Support systemic and local tested the vaccine Vaccine vaccine candidate Vaccines vector virus [DOI] 10.1128/JVI.00066-17 PMC 바로가기 [Article Type] Article