Materials-based vaccines for infectious diseasesReview Published on 2022-09-012023-07-09 Journal: Wiley interdisciplinary reviews. Nanomedicine and [Category] COVID19(2023년), [키워드] adjuvant Antigen immune response Infectious disease pathogen Vaccine [DOI] 10.1002/wnan.1824 PMC 바로가기 [Article Type] Review
Mesenchymal stem cell treatment for hyperactive immune response in patients with COVID-19COVID-19 환자의 과민성 면역 반응을 위한 중간엽 줄기세포 치료Review Published on 2022-09-012022-09-11 Journal: Immunotherapy [Category] COVID19(2023년), SARS, 변종, [키워드] Biomarker Biomarkers clinical clinical immunology clinical trials COVID-19 COVID-19 mortality COVID-19 patients CRP Cytokines decrease Effect effective Endothelitis epithelial cells Human immune system IL-6 immune response immune system independent invasive mesenchymal stem cell Mesenchymal stem cells MSC MSC therapy MSCs organism patients with COVID-19 potential treatment option pro-inflammatory cytokine pro-inflammatory cytokines PROTECT reduction in regenerative regimen reported Respiratory failure Safe sick stem cell stem cells systemic systemic effects therapy Treatment Trial [DOI] 10.2217/imt-2021-0245 PMC 바로가기 [Article Type] Review
A third dose of the BNT162b2 mRNA vaccine significantly improves immune responses among liver transplant recipientsBNT162b2 mRNA 백신의 세 번째 접종은 간 이식 환자의 면역 반응을 크게 향상시킵니다Article Published on 2022-09-012022-09-12 Journal: Journal of hepatology [Category] Fulltext, MERS, 진단, [키워드] Adverse adverse effect adverse effects age Anti-RBD IgG anti-SARS-CoV-2 antibody Antibody Response binding domain BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine Booster vaccine cellular immune responses cellular response center correlated determine dose doses Effect evaluate evaluated Factor fatigue Follow-up geometric humoral humoral immune response IgG immune immune response Immunity Immunosuppression immunosuppressive medications IMPROVE inhibitor liver liver transplant recipients local pain majority male median age Mild monotherapy neutralizing antibody Older age Patient predict RBD recipient recipients reported response Side effect side effects BNT162b2 mRNA vaccine significantly solid organ transplant T-cell the patient third dose Treatment Vaccine vaccine dose [DOI] 10.1016/j.jhep.2022.03.042 PMC 바로가기 [Article Type] Article
Antibody response against SARS-CoV-2 variants of concern in children infected with pre-Omicron variants: An observational cohort studyObservational Study Published on 2022-09-012022-10-06 Journal: EBioMedicine [Category] SARS, 변종, 진단, [키워드] acute phase Adults age analysed Analysis anti-Spike IgG Anti-spike IgG antibody antibodies Antibody Response Asymptomatic BBIBP-CorV BNT162b2 children Cohort COVID-19 decrease Delta dose Effectiveness evaluated Gender IgG titer immune response inactivated include infected children infected with SARS-CoV-2 Infection Lineage Mild mRNA vaccines mRNA-1273 Neutralising activity observation Observational cohort study omicron pediatric pediatric COVID-19 plasma Post-infection Prevent promotion Reinfection remained reported required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant seropositive significantly increased specificity stratified sustained Symptom the antibody response those with comorbidities vaccination Vaccination strategy Vaccines variant variants Wuhan [DOI] 10.1016/j.ebiom.2022.104230 PMC 바로가기 [Article Type] Observational Study
Taxonomical and functional changes in COVID-19 faecal microbiome could be related to SARS-CoV-2 faecal loadArticle Published on 2022-09-012022-11-16 Journal: Environmental microbiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Activation acute respiratory syndrome alteration caused changes in clearance contribute coronavirus COVID-19 COVID-19 disease COVID-19 pathogenesis COVID-19 severity exploratory study faece functional gastrointestinal tract GI symptoms gut microbiota highlight immune response Infection intestinal intestinal permeability mechanism Microbiome microbiota mitigate molecular function organ pandemic profile respiratory tract SARS-CoV-2 SARS-CoV-2 RNA severity the SARS-CoV-2 therapeutic strategy virus [DOI] 10.1111/1462-2920.16028 PMC 바로가기
The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay HarmonizationArticle Published on 2022-08-312022-11-15 Journal: mSphere [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome addition Analysis anti-SARS-CoV-2 assay harmonization assays calibration center coordinating coronavirus COVID-19 Depth develop ELISA enzyme-linked immunosorbent facilitate Frederick harmonization immune response Immunoglobulin IMPROVE International Interpretation multiplex National Cancer Institute network Neutralization assay Performance metrics plan protocol reported Research SARS-CoV-2 Science serological Serological assay Serological testing serology SeroNet standard reference standardized protocol supported Vaccines WHO [DOI] 10.1128/msphere.00193-22 PMC 바로가기
Humoral and Cellular Immune Responses to Vector, Mix-and-Match, or mRNA Vaccines against SARS-CoV-2 and the Relationship between the Two Immune ResponsesArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 진단, 치료기술, [키워드] Abbott acute respiratory syndrome Affect affected affecting age age and sex analyzed anti-SARS-CoV-2 antibody Antibody detection BAU binding antibody unit BNT162b2 cellular Cellular immune response cellular immune responses ChAdOx1 nCoV-19 coronavirus correlation Cutoff demonstrated determine Effect Elecsy evaluated Factor female first vaccination Genscript group humoral humoral immune responses immune immune response immune responses interferon gamma investigated male mix-and-match vaccine mRNA mRNA vaccine mRNA-1273 neutralizing antibody predict Qiagen QuantiFERON RBD regimen regimens relationship response robust Roche SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 neutralization second vaccination Sex subject T cell response T cell responses the receptor-binding domain vaccination Vaccine vaccine group vector vector vaccine venous blood was collected were used [DOI] 10.1128/spectrum.02495-21 PMC 바로가기
Immune response in ofatumumab treated multiple sclerosis patients after SARS-CoV-2 vaccinationArticle Published on 2022-08-312022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] alteration anti-CD20 anti-CD20 therapy antibody applied approach B cell caused CD4 Cellular immune response cellular immunity characterized Complete decrease Delta disorder dosage Effect elicit Frequency healthy controls humoral humoral immune response immune Immune cell immune cells immune response Immunosuppression implication information investigated mean treatment duration Multiple multiple sclerosis neutralization capacity Ofatumumab ofatumumab. omicron pandemic Patient preserved Regulatory T cell SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 variant sclerosis subcutaneously subpopulation sustained T cell T cell response T helper Th1 titer treated treated patient Treatment Tregs vaccination was impaired wild type [DOI] 10.3389/fimmu.2022.980526 PMC 바로가기
Protective Immunity of COVID-19 Vaccination with ChAdOx1 nCoV-19 Following Previous SARS-CoV-2 Infection: A Humoral and Cellular InvestigationArticle Published on 2022-08-302022-11-15 Journal: Viruses [Category] SARS, 진단, [키워드] activated acute respiratory syndrome antibody Antibody Response caused CD4+ naïve Cell cellular Cellular and humoral immunity cellular response ChAdOx1 ChAdOx1 nCoV-19 Cohort COVID-19 COVID-19 group D-dimer level DAV death effective faster humoral Humoral immunity Hybrid immunity IFN-γ IgG immune response Immunity increase in individual individuals induce infected individual interferon-γ investigated investigation Lymphocytes memory memory B cells naïve neutralizing antibody positive correlation SARS-CoV-2 SARS-CoV-2 vaccine secretion significant difference Support triggered vaccinated individual vaccination Vaccine with COVID-19 [DOI] 10.3390/v14091916 PMC 바로가기
A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus InfectionArticle Published on 2022-08-302023-06-12 Journal: mBio [Category] B형 간염, Fulltext, [키워드] antibody CHB functional cure HBsAg HBV infection immune response mRNA [DOI] 10.1128/mbio.01612-22 PMC 바로가기