Gastrointestinal Manifestations and Associated Health Outcomes of COVID-19: A Brazilian Experience From the Largest South American Public HospitalOriginal Article Published on 2020-10-212022-10-31 Journal: Clinics [Category] COVID-19, MERS, SARS, [키워드] 95% CI Analysis Brazil Chronic kidney disease clinically cohort study COVID-19 COVID-19 case determine experience fatigue Gastrointestinal Gastrointestinal symptom gastrointestinal symptoms Gender Health hospital Hospitalization ICU ICU admission immunosuppressants Immunosuppression in-hospital mortality increased mortality Laboratory Laboratory results male manifestation Manifestations mechanical ventilation medications Mortality myalgia not differ Older age outcome outcomes pandemic Patient patients with COVID-19 performed predictor presenting symptoms Prevalence prevalent Public Regression reported SARS-CoV-2 single-center South South America Symptom Symptoms vasopressor support were recorded with COVID-19 [DOI] 10.6061/clinics/2020/e2271 PMC 바로가기 [Article Type] Original Article
A Machine Learning Explanation of the Pathogen-Immune Relationship of SARS-CoV-2 (COVID-19), and a Model to Predict Immunity and Therapeutic Opportunity: A Comparative Effectiveness Research StudyOriginal Paper Published on 2020-10-192022-10-29 Journal: Jmirx Med [Category] COVID-19, [키워드] 95% CI Accuracy age Algorithm association Asymptomatic asymptomatic patient AUROC build carrier Cell characteristic China Chinese Clinical data Comorbidities Comparative Contact COVID-19 COVID-19 immunity COVID-19 symptom diagnosed differentiator District Effectiveness excluded explanation extreme Factor female growth hospital identify immune immune factor immune factors Immunity immunological individual infect infected with COVID-19 Infectious disease M-CSF machine machine learning machine learning analysis Macrophage male mass vaccinations median age Model objective observation Outbreaks outcome Patient patients patients with COVID-19 point of care positive predict predicted primary care Primary outcome programming public health relationship Research Result RT-PCR SARS-CoV-2 SCGF-β selected Sex single-center statistical statistically significant stem-cell growth factor-beta Symptom symptomatic symptomatic case Testing Therapeutics therapy Treatment treatment for COVID-19 understanding Vaccine were measured were recorded with COVID-19 [DOI] 10.2196/23582 PMC 바로가기 [Article Type] Original Paper
Development of a multivariate prediction model of intensive care unit transfer or death: A French prospective cohort study of hospitalized COVID-19 patients중환자실 이송 또는 사망의 다변수 예측 모델 개발: 입원한 COVID-19 환자에 대한 프랑스 전향 코호트 연구Research Article Published on 2020-10-192022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] 9-point ordinal scale 95% CI acute respiratory syndrome Admission age C-index calibration calibration curve Care Chain Reaction clinical clinical scale cohort study coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient death defined Department development discharge discrimination European population evaluated Factor France French Health Organization hospital Hospitalized hospitalized COVID-19 patient ICU identify increased risk intensive care intensive care unit internal internal medicine laboratory-confirmed lymphocyte Lymphocytes management Medicine moderate multivariable logistic regression multivariable logistic regression models Older age Ordinal Scale outcome Paris Patient patients patients hospitalized positive predicted Probability Prognostic factor Prognostic factors prospective cohort study R 2 respiratory reverse transcriptase risk scoring system single-center transfer university hospital Ventilation was performed were assessed WHO World Health Organization [DOI] 10.1371/journal.pone.0240711 PMC 바로가기 [Article Type] Research Article
Clinical characteristics and survival analysis in critical and non-critical patients with COVID-19 in Wuhan, China: a single-center retrospective case control studyArticle Published on 2020-10-162022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 치료기술, 치료법, 치료제, [키워드] Analysis antibiotic Antibiotics anticoagulation case control study caused Characteristics China clinical Clinical course contributed Corticosteroid COVID-19 COVID-19 patient Critical critical condition critical patient D-dimer demographic elevated Epidemic epidemiological fibrinogen High-sensitivity C-reactive protein Hospitalized hsCRP IL-6 In-hospital death in-hospital mortality Infectious diseases Inpatient Laboratory tests lymphocyte Multivariable regression outbreak outcome Oxygen therapy Patient patient survival patients patients with COVID-19 Platelet positive Predictive qSOFA reported Respiratory tract diseases retrospective risk factor Risk factors single-center SOFA score survival the SARS-CoV-2 Tongji Hospital Treatment Wuhan Wuhan, China [DOI] 10.1038/s41598-020-74465-3 PMC 바로가기 [Article Type] Article
Clinical characteristics and outcomes among hospitalized adults with severe COVID-19 admitted to a tertiary medical center and receiving antiviral, antimalarials, glucocorticoids, or immunomodulation with tocilizumab or cyclosporine: A retrospective observational study (COQUIMA cohort)Research article Published on 2020-10-152022-10-05 Journal: EClinicalMedicine [Category] 치료제, [키워드] Acute respiratory insufficiency Admission affected age Antiviral antivirals baseline Basic science boost C-reactive protein carried Characteristics clinical Clinical outcome clinical outcomes clinical trial Cohort collected Comorbidities Comorbidity COVID-19 COVID-19 outbreak COVID-19 research cyclosporine A demographic diabete Diabetes Mellitus Diagnosis died disease Diseases epidemiological Factor finding funding Glucocorticoids health system Hospitalized Hydroxychloroquine Hyperinflammation state hyperinflammatory phase hypertension immunosuppressants implication in-hospital mortality Inflammatory laboratory data male Mortality multivariate logistic regression multivariate model nasal swab Non-survivors observation Odds ratio Older age outcome paO2/fiO2 pathway Patient Positive test potential risk receiving reduce retrospective risk of death RT-PCR assay SARS-COV-2 infection severe COVID-19 severe COVID-19 patients significant decrease single-center Spanish subject survivor therapy Tocilizumab tocilizumab therapy Treatment [DOI] 10.1016/j.eclinm.2020.100591 [Article Type] Research article
Pro- and Anti-Inflammatory Responses in Severe COVID-19-Induced Acute Respiratory Distress Syndrome—An Observational Pilot StudyImmunology Published on 2020-10-062022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory distress syndrome analyzed Anti-inflammatory anti-inflammatory cytokine antibody production Antibody Response ARDS B cell B cell response CD8+ CD8+ T cells cellular response characterized collected coronavirus 2 Coronavirus disease 2019 COVID-19 Cytokine analysis Cytokines decrease died elevated flow-cytometry growth growth differentiation factor 15 ICU ICU treatment IgM IL-10 IL-6 immune defense immune response Immunoglobulin Inflammation intensive care Interaction interleukin longitudinal Lymphocyte count Lymphocyte subsets lymphocytopenia mechanism naïve natural killer NK cell objective Patient Pro Protein RBD Receptor binding domain Resilience respiratory response Result Retrospective study routine clinical care SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 severe ARDS severity single-center slight increase spike suffered syndrome T helper cells tissue upregulated [DOI] 10.3389/fimmu.2020.581338 PMC 바로가기 [Article Type] Immunology
The impact of COVID-19 on gastric cancer surgery: a single-center retrospective studyResearch Article Published on 2020-10-022022-10-28 Journal: BMC Surgery [Category] COVID-19, MERS, SARS, [키워드] addition Admission Cancer Cancer patients chest CT scan clinical outcomes coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 crisis COVID-19 group defined enrolled Gastric cancer global pandemic Hospital stay Hospitalization pandemic Patient performed provide Result Retrospective analysis Retrospective study single-center surgical two groups World Health Organization [DOI] 10.1186/s12893-020-00885-7 PMC 바로가기 [Article Type] Research Article
Exposure risk of patients with chronic infectious wounds during the COVID-19 outbreak and its countermeasuresResearch Article Published on 2020-10-022022-10-30 Journal: Journal of Orthopaedic Surgery and Research [Category] COVID-19, MERS, SARS, [키워드] age average cardiovascular disease cause caused China Chronic diseases chronic wound Chronic wounds Clinical characteristics Clinical outcome collected common Comorbidities Comorbidity coronavirus COVID-19 COVID-19 epidemic COVID-19 outbreak cured demographic demonstrated diabete diabetes discharged exposure Gout high risk High-risk populations hospital Hospitalization hypertension include independent risk factor individuals Infection infective information Kidney injury Laboratory majority male management no significant difference novel coronavirus pneumonia outbreak Patient Pneumonia potential for transmission Prognostic factors Result retrospective Retrospective study risk single-center the patient tissue were infected β-coronavirus [DOI] 10.1186/s13018-020-01976-0 PMC 바로가기 [Article Type] Research Article
Clinical efficacy of glucocorticoid on the treatment of patients with COVID-19 pneumonia: A single-center experienceResearch article Published on 2020-10-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] SARS, 치료법, [키워드] adverse event adverse events C-reactive protein (CRP China city clinical Clinical course Clinical efficacy collected COVID-19 determine dosage Efficacy Fever glucocorticoid Glucocorticoid therapy Glucocorticoid treatment groups identify Inflammatory response inhibit investigated laboratory parameter low-dose Methylprednisolone nucleic acid outcome Patient patients with COVID-19 Pneumonia protective immune response pulmonary significantly single-center the timing therapy Treatment Wuhan [DOI] 10.1016/j.biopha.2020.110529 [Article Type] Research article
Varied clinical presentation and outcome of SARS-CoV-2 infection in liver transplant recipients: Initial experience at a single center in Madrid, Spain간 이식 환자에서 SARS-CoV-2 감염의 다양한 임상 양상 및 결과: 스페인 마드리드의 단일 센터에서 초기 경험Observational Study Published on 2020-10-012022-09-11 Journal: Transplant infectious disease : an official journa [Category] MERS, SARS, 임상, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered age baseline broad spectrum consequence coronavirus COVID-19 CT scan diagnosed died discharged home disease severity Drug interactions Dyspnea females Fever Follow-up Hydroxychloroquine immunomodulatory therapy Immunosuppression incidence Infection interferon liver Liver function liver transplant Lopinavir Lopinavir/ritonavir median median age modify one patient onset of symptoms outcome Outpatient Pandemics Patient patients patients with COVID-19 Pneumonia Prognosis question recipients regimen remained respiratory Ritonavir SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 severe acute respiratory syndrome Coronavirus single center single-center Spain still hospitalized Symptoms therapy Tocilizumab transplantation Two patient two patients was used X-ray [DOI] 10.1111/tid.13372 PMC 바로가기 [Article Type] Observational Study