Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?숙주 유전자와 Mycobacterium tuberculosis 계통 간의 상호 작용은 결핵 중증도에 영향을 줄 수 있습니다. 공진화의 증거?Research Article Published on 2020-04-302022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addition Affect affected allele alleles animal model animal models association co-occurrence Cohort Combination Contact disease risk disease severity DNA examined explain explained Genetic studies Genetic variation genetics Genome genomes Genotype Host host gene Human human allele Human genetics human host Hypothesis IL12B increased risk independent Infectious disease Infectious diseases Interaction Lineage modulate Mycobacterium tuberculosis nucleotide other infectious diseases patient cohort polymorphism promote reduce replicated risk severe disease severity Severity of disease significant interaction single nucleotide Single nucleotide polymorphism SLC11A1 SNP SNPs susceptibility tested Tuberculosis Uganda unit Variation [DOI] 10.1371/journal.pgen.1008728 PMC 바로가기 [Article Type] Research Article
Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infectionsResearch Perspective Published on 2020-04-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, [키워드] affecting age Betacoronavirus clinical evaluation Comorbidity coronavirus COVID-19 COVID-19 pandemic decrease described disease Diseases Efficacy elderly patients frailty highlight immune function immune system immunosenescence indicate Infection infection rate infection rates infections Intervention investigated limitations loss of function marker medication Older Population previous study rapalog Rapamycin reduce Research responsible SARS-CoV-2 severity Sirolimus the disease therapeutic intervention vaccination while [DOI] 10.18632/aging.102988 PMC 바로가기 [Article Type] Research Perspective
Probable Exit Strategy Against COVID-19 of Low Resource Country like Nepal: Open Floor DiscussionView Point Published on 2020-04-302022-10-30 Journal: JNMA: Journal of the Nepal Medical Association [Category] COVID-19, SARS, [키워드] exit strategy Against approach average consequence Contact tracing country COVID-19 disrupting distress effective exit extreme extreme social distancing floor Follow-up Infection Isolation lifted lockdown maintain Nepal reopening SARS-CoV-2 second wave severity Spread Strategy Trial virus [DOI] 10.31729/jnma.4974 PMC 바로가기 [Article Type] View Point
Correlation between Heart fatty acid binding protein and severe COVID-19: A case-control studyResearch Article Published on 2020-04-292022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] all-cause mortality binding calculated case-control study chi-square test Chinese clinical confidence interval correlation COVID-19 determine diagnosed diagnosis of COVID-19 elevated fatty Features heart Hospital stay Hospitalization inclusion criteria marker Mild Patient patients predict progressed Protein Registered registry Result screened serum severe COVID-19 severity severity of COVID-19 tested the patient [DOI] 10.1371/journal.pone.0231687 PMC 바로가기 [Article Type] Research Article
Gender Differences in Patients With COVID-19: Focus on Severity and MortalityCOVID-19 환자의 성별 차이: 심각도와 사망률에 초점Public Health Published on 2020-04-292022-09-06 Journal: Frontiers in Public Health [Category] Communicable Disease, COVID-19, MERS, SARS, [키워드] age Beijing Case series case sery China Comorbidities comparable coronavirus disease COVID-19 data set data sets death deaths Deceased died difference female female patient focus Gender gender role hospitalized patient independent independent of male men men and women morbidity Mortality novel Novel coronavirus novel coronavirus disease number of comorbidity Older age outbreak outcome Patient patients who survived patients with SARS Prevalence risk SARS SARS patients SARS-CoV-2 severity survived treated while with COVID-19 women [DOI] 10.3389/fpubh.2020.00152 PMC 바로가기 [Article Type] Public Health
Health belief model for coronavirus infection risk determinantsOriginal Article Published on 2020-04-282022-10-29 Journal: Revista de Saúde Pública [Category] COVID-19, MERS, SARS, [키워드] approach cause Complete Comportamento de Redução do Risco composed Conhecimentos, Atitudes e Prática em Saúde Coronavirus infection Coronavirus Infections, prevention & control Coronavirus Infections, psychology determinant dimensions excluded FIVE group Health Health Belief Model health knowledge, attitudes, practice Infecções por Coronavirus, prevenção & controle Infecções por Coronavirus, psicologia infection risks less measure Neste Novel coronavirus infection perceived benefit profile public health Quantitative quantitative value question questionnaire reliability reproducibility response risk Risk perception Risk reduction behavior severity Significant Standard deviation susceptibility Validity verbal [DOI] 10.11606/s1518-8787.2020054002494 PMC 바로가기 [Article Type] Original Article
Clinical utility of cardiac troponin measurement in COVID-19 infectionMini Review Published on 2020-04-272022-10-27 Journal: Annals of Clinical Biochemistry [Category] COVID-19, [키워드] acute respiratory syndrome Analytes cardiac troponin Cardiac troponin I cardiac troponin T cardiovascular disease cause clinical Concentration Confusion coronary syndrome COVID-19 COVID-19 infection COVID-19 patient creating cTn detrimental effect disease global pandemic greater higher risk human-to-human transmission increased mortality Interpretation Isolation majority mechanism Mental Mild-to-moderate Mortality Myocardial infarction novel coronavirus SARS-CoV-2 pathophysiological mechanism Patient physical activity positive public health emergency reported Respiratory disease SARS-CoV-2 severe disease progression severity social distancing Symptoms the disease treatment regimens troponin utility while [DOI] 10.1177/0004563220921888 PMC 바로가기 [Article Type] Mini Review
Clinical utility of cardiac troponin measurement in COVID-19 infectionMini Review Published on 2020-04-272022-10-27 Journal: Annals of Clinical Biochemistry [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Analytes cardiac troponin Cardiac troponin I cardiac troponin T cardiovascular disease cause clinical Concentration Confusion coronary syndrome COVID-19 COVID-19 infection COVID-19 patient creating cTn detrimental effect disease global pandemic greater higher risk human-to-human transmission increased mortality Interpretation Isolation majority mechanism Mental Mild-to-moderate Mortality Myocardial infarction novel coronavirus SARS-CoV-2 pathophysiological mechanism Patient physical activity positive public health emergency reported Respiratory disease SARS-CoV-2 severe disease progression severity social distancing Symptoms the disease treatment regimens troponin utility while [DOI] 10.1177/0004563220921888 PMC 바로가기 [Article Type] Mini Review
Hyperglycemia, hydroxychloroquine, and the COVID‐19 pandemicReview Published on 2020-04-272022-10-30 Journal: Journal of medical virology [Category] COVID-19, SARS, [키워드] abrogate ACE2 acute respiratory distress agent antibody‐mediated cell‐mediated cytotoxicity Antiviral agents appear ARDS blunt Concentration Course COVID‐19 diabetes Diabetes Mellitus disease enzyme explained glycosylated glycosylation Hydroxychloroquine hyperglycemia Inflammatory response interfere lung epithelium Macrophage macrophage polarization mechanism neutralizing antibody overactive pandemic Pathogenesis Protein pulmonary immune response receptor SARS Coronavirus SARS‐CoV‐2 severity Spike protein susceptible patients symptom onset syndrome the disease Viral load viral particle [DOI] 10.1002/jmv.25887 PMC 바로가기 [Article Type] Review
COVID-19 pandemic—a focused review for cliniciansArticle Published on 2020-04-252022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, SARS, [키워드] caused Characteristics Clinical course Clinical management Clinical practice clinician Clinicians content coronavirus COVID-19 COVID-19 pandemic COVID19 Diagnosis diagnostic diagnostics Efficacy Health high risk management manuscript marker Mortality Novel coronavirus objective Patient peer-reviewed Probability qRT-PCR radiological SARS-CoV-2 serology Severe case severity Source Treatment viral shedding Virological [DOI] 10.1016/j.cmi.2020.04.023 PMC 바로가기 [Article Type] Article