Peripheral Inflammatory Cytokines and Lymphocyte Subset Features of Deceased COVID-19 PatientsResearch Article Published on 2021-01-222022-10-27 Journal: BioMed Research International [Category] COVID-19, MERS, [키워드] Analysis analyzed B cell Cell cell counts cells collected correlated COVID-19 Cytokine storm death death in COVID-19 Deceased decrease feature helper T cells Hyperinflammatory IL-10 IL-6 IL-8 independent predictor indicated induce Inflammatory cytokine lymphocyte Lymphocyte subset Lymphocyte subsets lymphopenia multivariate NK cell objective outcome Patient patients peripheral predict remained Result Retrospective study ROC Curve SARS-CoV-2 significantly subset survival survivor Survivors T cell T cells Tongji Hospital with COVID-19 Wuhan, China [DOI] 10.1155/2021/9101082 PMC 바로가기 [Article Type] Research Article
Peripheral Inflammatory Cytokines and Lymphocyte Subset Features of Deceased COVID-19 Patients사망한 COVID-19 환자의 말초 염증성 사이토카인 및 림프구 하위 집합 특징Research Article Published on 2021-01-222022-09-10 Journal: BioMed Research International [Category] 바이오마커, [키워드] (suppressor T cells Analysis analyzed B cell Cell cell counts cells collected correlated COVID-19 COVID-19 patients cytokine Cytokine storm death death in COVID-19 Deceased decrease feature helper T cells Hyperinflammatory Hyperinflammatory response IL-10 IL-6 IL-8 independent predictor independent predictors indicated induce Inflammatory cytokine Inflammatory cytokines lymphocyte Lymphocyte subset Lymphocyte subsets lymphopenia multivariate multivariate analyses NK cell objective outcome Patient patients peripheral predict remained Result Retrospective study ROC Curve SARS-CoV-2 significantly subset survival survival time survivor Survivors T cell T cells Tongji Hospital with COVID-19 Wuhan Wuhan, China [DOI] 10.1155/2021/9101082 PMC 바로가기 [Article Type] Research Article
Obesity is associated with severe COVID-19 but not death: a dose−response meta-analysisOriginal Paper Published on 2021-01-052022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, [키워드] 95% CI 95% confidence interval Admission Affect Analysis BMI Cochrane Library coronavirus disease COVID-19 COVID-19 patient COVID-19 patients database death in COVID-19 develop Epidemic ICU identify increase in increased risk Invasive mechanical ventilation Meta-analysis Mortality obese COVID-19 patient obesity Odds ratio Patient patients with COVID-19 Prevalence Prognosis progression random-effects model severe COVID-19 severity Web of Science were used [DOI] 10.1017/S0950268820003179 PMC 바로가기 [Article Type] Original Paper
Markers Associated with COVID-19 Susceptibility, Resistance, and SeverityReview Published on 2020-12-302022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory syndrome age ARDS coronavirus coronavirus disease correlation COVID-19 Cytokine storm death death in COVID-19 develop Factor Host immune reaction infected with SARS-CoV-2 initial medical condition mortality rate outbreak pandemic Pathogenesis patients pro-inflammatory resistance SARS SARS-CoV-2 Severe infection severe symptom severity shown susceptibility syndrome Viral pneumonia WHO with COVID-19 World Health Organization Wuhan, China [DOI] 10.3390/v13010045 PMC 바로가기 [Article Type] Review
Chest CT–derived pulmonary artery enlargement at the admission predicts overall survival in COVID-19 patients: insight from 1461 consecutive patients in ItalyChest Published on 2020-12-232022-10-31 Journal: European Radiology [Category] COVID-19, MERS, SARS, [키워드] adjusted Admission age analyzed association blinded Chest CT Clinical data Clinical findings Cohort cohort study consecutive patient COVID-19 COVID-19 patient COVID-19 patients creatinine CT measurement death in COVID-19 derivation enlargement evaluated extension Features final multivariable model Gender hazard ratio hospital hospitals Hypertension, pulmonary in-hospital mortality independent IQR Italy lung Lung CT main pulmonary artery male males Model Mortality multivariable Non-COVID-19 objective Patient performed Pneumonia Point predict Prognostic value pulmonary artery pulmonary hypertension regression analysis Result risk stratification Seven submitted supplementary material survival the median Thorax Tomography, X-Ray Computed validation cohort Volume was tested [DOI] 10.1007/s00330-020-07622-x PMC 바로가기 [Article Type] Chest
Defining heart disease risk for death in COVID-19 infectionCOVID-19 감염에서 사망에 대한 심장 질환 위험 정의Article Published on 2020-12-012022-09-11 Journal: QJM: An International Journal of Medicine [Category] MERS, SARS, 바이오마커, [키워드] 95% CI acute coagulopathy Acute kidney injury acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission analyzed arrhythmia cardiovascular cardiovascular disease clinical observation clinical observations clinically evaluated collected Comorbidities Complication coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patient COVID-19 patients CVD death death in COVID-19 demographic demographic data disease disease risk glucocorticoid independent risk factor independent risk factors Infection intensive care intensive care unit admission Intervention Laboratory laboratory findings laboratory-confirmed SARS-CoV-2 infection mechanical ventilation men Mortality mortality rate multivariable Cox regression Older Older age outcome outcomes Patient patients with COVID-19 proportion respiratory respiratory distress SARS-COV-2 infection severe acute respiratory syndrome Coronavirus significantly syndrome therapy Treatment ventricular ventricular fibrillation ventricular tachycardia Vigilance Vitamin Vitamin C Wuhan Wuhan, China [DOI] 10.1093/qjmed/hcaa246 PMC 바로가기 [Article Type] Article
COVID-19: The Emerging Immunopathological Determinants for Recovery or DeathMicrobiology Published on 2020-12-012022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] activated Adaptive immune response adaptive immune system antibodies B cell response COVID-19 Critical Critically ill patient death in COVID-19 Deterioration determinant determine develop disease effective functional heterogeneous Host host cell host immune system immune immune response immune system immunopathological imperative implicated Infection initial interferon response involved knowledge lymphocytopaenia mechanism molecular outcome pathway Patient patients respiratory virus SARS-CoV-2 severe disease Stage Symptom T cell T cell response therapeutic interventions viral clearance viral evasion virus [DOI] 10.3389/fmicb.2020.588409 PMC 바로가기 [Article Type] Microbiology
Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST studyObservational Study Published on 2020-12-012022-10-04 Journal: European journal of internal medicine [Category] 임상, [키워드] addition analyses Analysis analyzed association C-reactive protein Clinical Center COVID-19 COVID-19 patients death death in COVID-19 disease severity elevated finding HCQ HCQ therapy hospitalised COVID-19 patient hospitalized patients Hydroxychloroquine In-hospital death in-hospital mortality Inflammation Inpatient Italian Italy laboratory-confirmed SARS-CoV-2 infection limit lower risk Mortality multicenter multicentre multivariable Patient patients hospitalized Potential treatment primary end-point Probability Randomized controlled trials receiving reduced Regression model retrospective secondary These data Treatment Weighting with COVID-19 [DOI] 10.1016/j.ejim.2020.08.019 PMC 바로가기 [Article Type] Observational Study
The clinical value of minimal invasive autopsy in COVID-19 patientsResearch Article Published on 2020-11-112022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] alteration alterations Autopsy Belgium biopsies changed clinical clinical information Confirmed COVID-19 infection contributed COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients death death in COVID-19 Deceased diagnose diagnoses Diagnosis diagnostic died discharge disease histological Histopathology hospital Hospitalization independent intensive care invasive less MIA outcome pandemic Patient patients PCR-confirmed prospective observational cohort Safe were assessed [DOI] 10.1371/journal.pone.0242300 PMC 바로가기 [Article Type] Research Article
Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19COVID-19의 기존 심혈관 질환 및 심혈관 손상의 기저에 있는 성별 차이Article Published on 2020-11-012022-09-11 Journal: Journal of molecular and cellular cardiology [Category] MERS, 유전자 메커니즘, 진단, [키워드] 2019 coronavirus disease ACE2 acute respiratory syndrome arrhythmia Basic science cardiac injury cardiovascular cardiovascular disease clinical observation contribute coronavirus coronavirus disease COVID-19 COVID-19 disease COVID-19 patients CVD death in COVID-19 deaths Disease progression Hospitalization In-hospital death Infection Injury leads male outcome pathogenic mechanism pathogenic mechanisms patients Perspective progression promote proportion reported respiratory Respiratory failure resulting risk risk factor SARS-CoV-2 Severe acute respiratory syndrome severe cases severe COVID-19 Sex sex differences thrombosis [DOI] 10.1016/j.yjmcc.2020.08.007 PMC 바로가기 [Article Type] Article