Susceptibility of Dog, Hamster, and Mouse Cells to the Replication-Competent Adenovirus 11p E1/E3 Green Fluorescence Protein Vector Has Implications for the Selection of Animal Vaccine ModelsMicrobiology Published on 2021-10-272022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Ad5 Adenovirus animal animal cells animal model Antigen can be used candidate CD46 Cell cell line cell lines cellular receptor CHO cells Critical cytotoxicity DNA replication dog dose E1/E3 vector Efficacy Express expressed expression Fluorescence generate GFP GFP expression green hamster host cell Human in vitro experiments infect infecting Infection manifested MDCK cells Model mouse not express Protein qPCR assay RCAd11pGFP SARS-CoV-2 vaccine Selection specificity susceptibility the vaccine Trial undetectable Vaccine Vaccines vector viral DNA virus virus infection virus particle [DOI] 10.3389/fmicb.2021.698999 PMC 바로가기 [Article Type] Microbiology
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Dog in Connecticut in February 20212021 년 2 월 코네티컷의 개에있는 심한 급성 호흡기 증후군 코로나 바이러스 2 (SARS-COV-2)Brief Report Published on 2021-10-232022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 conducted Connecticut coronavirus coronavirus 2 COVID-19 D614G diagnostic died dog dominant ENhance Epidemiology Genetic Genome sequencing HCoV Human identify In situ hybridization Laboratory Lineage multiple organ multiple organs Mutation negative Nsp12 P323L Phylogenetic analysis positive postmortem examination public health real time-PCR respiratory reverse transcription RNA RNAscope RT-qPCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus submitted substitutions sudden death The United States United States Viral Viral RNA virus Winter zoonotic [DOI] 10.3390/v13112141 PMC 바로가기 [Article Type] Brief Report
Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health ApproachSARS-COV2 감염 환자의 개 후각 감지: 하나의 건강 접근법Public Health Published on 2021-10-212022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 치료기술, [키워드] alternative approach axillar canine collected COVID-19 detect detection Diagnosis dog false-negative infected with COVID-19 invasive Latin America Negative predictive value odor olfactory one health positive Positive predictive value Predictive value qPCR sensitivity Swab Sweat Symptom Volunteer [DOI] 10.3389/fpubh.2021.647903 PMC 바로가기 [Article Type] Public Health
Near-Complete Genome of SARS-CoV-2 Delta (AY.3) Variant Identified in a Dog in Kansas, USASARS-COV-2 델타의 거의 완전한 게놈 (AY.3) 변형은 미국 캔자스의 개에서 확인Article Published on 2021-10-192022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis animal AY.3 canine change characterization Cluster coding region Collie Consensus coronavirus COVID-19 COVID-19 disease Delta delta variant description dog house Human Identified infecting Infection Local outbreak Phylogenetic positive respiratory SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants sequence sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 susceptibility Symptom tested Transmission underlying conditions unique USA variant virus whole genome sequence [DOI] 10.3390/v13102104 PMC 바로가기 [Article Type] Article
Genome editing in large animal modelsReview article Published on 2021-10-012022-10-05 Journal: Molecular therapy : the journal of the American So [Category] 비임상, [키워드] Anatomy animal model animal models Base editor Blood Cancer cellular clinical dosing CRISPR DMD dog evaluated ex vivo gene therapy genetic disease Genome Genome editing greater Hemoglobinopathies HIV-1 Host immune response human diseases Human immunodeficiency virus humans immunology implementation in vivo gene therapy Infection lack large animal models Lipid nanoparticle locus meganuclease mice mouse model muscular nanoparticle NHPs non-human primate Nuclease overcome pathology pig preclinical models regimen repeated Retinal diseases short-lived therapy tissue transgene treat Treatment ZFN [DOI] 10.1016/j.ymthe.2021.09.026 [Article Type] Review article
Highly sensitive scent-detection of COVID-19 patients in vivo by trained dogs훈련 된 개에 의한 생체 내에서 Covid-19 환자의 매우 민감한 향기 감지Research Article Published on 2021-09-292022-09-10 Journal: PLoS ONE [Category] SARS, 치료기술, 치료법, [키워드] Accuracy canine Compound conditions Contamination COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 positive patient detect Diagnosis diagnostic diagnostics Disease prevalence dog dropped Effectiveness Efficacy experiments Government Hospital staff hospitalized patient in vitro in vivo independent independent of infected individual infected individuals Infection limit of detection negative Negative predictive value odoriferous organic compounds Patient PCR testing Positive predictive value Predictive Predictive value Prevalence remained required respiratory rRT-PCR rRT-PCR testing SARS-CoV-2 Scent screening test secretion sensitivity specificity specimen subjects Symptoms System the patient the scent Trial unique variables Volunteer were used [DOI] 10.1371/journal.pone.0257474 PMC 바로가기 [Article Type] Research Article
Seroprevalence of antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) in household dogs in JapanArticle Published on 2021-09-242023-06-15 Journal: The Journal of veterinary medical science [Category] MERS, SARS, [키워드] antibody Coronavirus disease 2019 dog severe acute respiratory syndrome coronavirus 2 [DOI] 10.1292/jvms.21-0338 PMC 바로가기
One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020인간의 Covid-19 사례가 확인 된 가구의 애완 동물 사이의 SARS-Cov-2 감염 및 혈청 양성에 대한 건강 조사-2020 년 우타와 위스콘신Article Published on 2021-09-122022-09-10 Journal: Viruses [Category] Fulltext, SARS, 조류인플루엔자, 치료기술, [키워드] cat Confirmed Contact contact with COVID-19 COVID-19 diagnosis detectable Diagnosis dog eight eligible enrolled for inclusion greater household household transmission Households Human Infection investigation laboratory-confirmed Laboratory-confirmed COVID-19 Limited median nasal one health Oropharyngeal Patient people with COVID-19 pets positive proportion rectal swab restrict rRT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibodies serological results seropositive Seropositivity Swab tested Transmission with COVID-19 zoonoses [DOI] 10.3390/v13091813 PMC 바로가기 [Article Type] Article
Low SARS-CoV-2 Seroprevalence and No Active Infections among Dogs and Cats in Animal Shelters with Laboratory-Confirmed COVID-19 Human Cases among EmployeesArticle Published on 2021-09-112022-10-28 Journal: Biology [Category] COVID-19, [키워드] animal animal shelter antibody cause collected coronavirus COVID-19 detectable dog employee event Human human-to-animal human-to-animal transmission implementation Infection prevention investigated laboratory-confirmed Neutralizing people with COVID-19 Probability risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission Seroprevalence simple specimen the United State transmission of SARS-CoV-2 Viral RNA virus were infected zoonosis [DOI] 10.3390/biology10090898 PMC 바로가기 [Article Type] Article
Animal Shelters’ Response to the COVID-19 Pandemic: A Pilot Survey of 14 Shelters in the Northeastern United StatesArticle Published on 2021-09-102022-10-28 Journal: Animals : an Open Access Journal from MDPI [Category] COVID-19, [키워드] adopted adoption affected Anecdotal animal animal shelter Care cat change COVID-19 COVID-19 pandemic dog euthanasia euthanized Evidence expand FIVE foster care greater not differ offer outcome pandemic peer-reviewed proportion provide recruit reported response significantly significantly lower simple Support survey t -test United State United States Variability were used while widespread Wilcoxon signed-rank test worldwide pandemic [DOI] 10.3390/ani11092669 PMC 바로가기 [Article Type] Article