immunomodulator – Page 5 – Communicable Diseases Research

Coronavirus Disease-Associated Mucormycosis from a Tertiary Care Hospital in India: A Case Series

Anesthesiology

Published on 2021-07-032022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] Admission CAM case sery Chemotherapy Clinical characteristics condition conditions COVID COVID-19 COVID-19 patient death Diabetes Mellitus disease early diagnosis Fungal infection Health higher odd hyperglycemia Immunocompromised immunomodulator immunomodulators incidence infect invasive malignancy median age Mortality Mucormycosis non-survivor Non-survivors opportunistic infection outcomes overall mortality pandemic progresses Patient patients with diabete Prevalence retrospective risk SARS-CoV-2 Sery severity single center steroid Steroids survival survivor Systemic steroid Tertiary Treatment use of steroids with COVID-19
[DOI] 10.7759/cureus.16152 PMC 바로가기 [Article Type] Anesthesiology

Does hydroxychloroquine still have any role in the COVID-19 pandemic?

하이드록시클로로퀸이 COVID-19 전염병에서 여전히 어떤 역할을 합니까?

Article

Published on 2021-07-012022-09-11
Journal: Expert opinion on pharmacotherapy [Category] SARS, 신약개발, 치료제,

[키워드] adoption Antiviral antiviral activity antiviral drug antiviral drugs Area benefit candidate Cardiotoxicity Chloroquine clinical trial clinical trials complex conditions controlled trials COVID-19 COVID-19 pandemic Dexamethasone dosage drug drugs Evidence experiment expert hospitalized patient hospitalized patients Hydroxychloroquine IL-6 IL-6 receptor antagonists immunomodulator immunomodulators in vitro data in vivo Infection Interpretation malaria pharmacokinetics prevention Randomized controlled trial RCT RCTs rheumatological safety profile SARS-CoV-2 severe COVID-19 Support therapeutic Tolerability Treatment widespread
[DOI] 10.1080/14656566.2021.1898589 PMC 바로가기 [Article Type] Article

Tofacitinib as an Adjunct Immunomodulator for Treatment of a Patient with Severe COVID-19: A Case Report

Case Report

Published on 2021-06-302022-10-30
Journal: JNMA: Journal of the Nepal Medical Association [Category] Coronavirus, SARS,

Shedding light on vitamin D: the shared mechanistic and pathophysiological role between hypovitaminosis D and COVID-19 risk factors and complications

Review

Published on 2021-06-292023-06-15
Journal: Inflammopharmacology [Category] MERS,

[키워드] COVID-19 Hypovitaminosis D immunomodulator Vitamin D Vitamin D receptor
[DOI] 10.1007/s10787-021-00835-6 PMC 바로가기 [Article Type] Review

Interleukin-1- Receptor Kinase 4 Inhibition: Achieving Immunomodulatory Synergy to Mitigate the Impact of COVID-19

인터루킨-1- 수용체 키나제 4 억제: COVID-19의 영향을 완화하기 위해 면역조절 시너지 달성

Immunology

Published on 2021-06-232022-09-12
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단,

[키워드] COVID-19 cytokine Cytokine release syndrome (CRS) immunomodulator Impact interleukin-1 irak4 kinase
[DOI] 10.3389/fimmu.2021.693085 PMC 바로가기 [Article Type] Immunology

Inflammatory Mechanisms in COVID-19 and Atherosclerosis: Current Pharmaceutical Perspectives

COVID-19 및 죽상동맥경화증의 염증 기전: 현재의 약학적 관점

Review

Published on 2021-06-212022-09-12
Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-inflammatory agents anti-inflammatory treatment Arrhythmias Atherosclerosis atherosclerotic atherosclerotic heart disease cardiovascular event Cardiovascular events cardiovascular system caused coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 current disease endothelial injury excess mortality heart disease immunomodulator immunomodulators Inflammation inflammatory pathway inflammatory pathways involved Mortality myocardial injury myocarditis pharmaceutical reduction SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe complications similarities similarity systemic inflammatory response thrombotic thrombotic event Treatment Venous Thromboembolism
[DOI] 10.3390/ijms22126607 PMC 바로가기 [Article Type] Review

Antiviral and immunological activity of zinc and possible role in COVID-19

아연의 항 바이러스 및 면역 학적 활성 및 Covid-19에서의 가능한 역할

Review

Published on 2021-06-152022-09-10
Journal: The British Journal of Nutrition [Category] 치료제,

Antiviral, Antibacterial, Antifungal, and Antiparasitic Properties of Propolis: A Review

Review

Published on 2021-06-112022-11-01
Journal: Foods [Category] COVID-19,

The role of human C5a as a non-genomic target in corticosteroid therapy for management of severe COVID19

중증 COVID19 관리를 위한 코르티코스테로이드 요법에서 비-게놈 표적으로서 인간 C5a의 역할

Article

Published on 2021-06-012022-09-12
Journal: Computational biology and chemistry [Category] MERS, SARS, 신약개발, 진단,

[키워드] activate acute respiratory syndrome amplified appear binding C3a C5a chemoattractant Circular Circular dichroism clinical evidence Colchicine combination therapy complement complement system contribute Coronavirus-2 corticosteroid therapy Corticosteroids COVID19 Cytokine storm Dexamethasone drug Effect Fluorescence globe Host immunomodulator indicate Inflammatory management moderate modulating molecular dynamics morbidity and mortality Neutralizing non-genomic non-specific pathophysiological Pathways physiological Polypharmacology positive Prednisone Prednisone. probe Prophylactic PROTECT reducing repurposing Safe SARS-CoV2 severity Signaling significantly small molecule drug triggered triggering Vaccine while
[DOI] 10.1016/j.compbiolchem.2021.107482 PMC 바로가기 [Article Type] Article

Anti-Inflammatory Treatment of COVID-19 Pneumonia With Tofacitinib Alone or in Combination With Dexamethasone is Safe and Possibly Superior to Dexamethasone as a Single Agent in a Predominantly African American Cohort

Research article

Published on 2021-06-012022-10-05
Journal: Mayo Clinic Proceedings: Innovations, Quality & Outcomes [Category] 치료법,

[키워드] addition adjusted adjusted odds ratio African American age agent Anti-inflammatory therapy AORadjusted odds ratio benefit C-reactive protein center clinical parameter Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19coronavirus disease 2019 CRPC-reactive protein CTComputed Tomography death Delta Delta Regional Medical Center Dexamethasone discharged DRMCDelta Regional Medical Center Eligible patients group hospital Hospitalization Hospitalized hospitalized patient ILInterleukin immunomodulator in-hospital mortality inhibitor interleukin JAKJanus kinase janus Janus kinase objective Odds ratio OROdds Ratio Other Patient PCRpolymerase chain reaction Pneumonia polymerase chain reaction Primary outcome proportion reduction in Regional Result retrospective Signal transducer and activator of transcription single-center STATSignal transducer and activator of transcription Superior survival Tofacitinib Transcription treated Treatment treatment regimen
[DOI] 10.1016/j.mayocpiqo.2021.03.007 [Article Type] Research article