Are angiotensin converting enzyme (ACE1/ACE2) gene variants associated with the clinical severity of COVID-19 pneumonia? A single-center cohort study안지오텐신 전환 효소(ACE1/ACE2) 유전자 변이가 COVID-19 폐렴의 임상 중증도와 관련이 있습니까? 단일 센터 코호트 연구Article Published on 2022-02-012022-09-11 Journal: Anatolian journal of cardiology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] abnormality ACE ACE gene ACE1 ACE1 gene ACE1/ACE2 ACE2 ACE2 gene Admission age allele Analysis angiotensin angiotensin converting enzyme automated Bioinformatics analysis Clinical characteristics Clinical severity Cohort cohort study coronavirus disease Coronavirus disease 2019 COVID-19 determine disease severity DNA domain DSP enzyme exon 1 frequencies Frequency functional Genetic Genomic DNA Genotype group I/D polymorphism ICU independent predictor independent predictors intensive care intensive care unit investigated knowledge no effect non-ICU Older age other variant pandemic Patient patients hospitalized Peripheral blood peripheral blood lymphocyte peripheral blood lymphocytes Pneumonia polymorphism Polymorphisms purified radiologic recent Sanger sequencing Science Sequencing analysis severe disease single-center statistical analysis Statistical Package variant was performed was used [DOI] 10.5152/AnatolJCardiol.2021.502 PMC 바로가기 [Article Type] Article
Characteristics and Prognostic Factors of Pulmonary Fibrosis After COVID-19 PneumoniaMedicine Published on 2022-01-312022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Admission alveolar Analysis analyzed Computed tomography consecutive patient consolidation Coronavirus disease 2019 COVID-19 COVID-19 infection discharge disease evaluated Factor Follow-up ground-glass opacity High-resolution high-resolution computed tomography Hospital admission Hospital stay Hospitalization HRCT In-hospital independent predictor initial interstitial lung abnormality men Older P/F Patient patients persistence Pneumonia predict predictor pulmonary pulmonary fibrosis pulmonary sequelae radiological radiological abnormality REC Result SARS-CoV-2 semiquantitatively [DOI] 10.3389/fmed.2021.823600 PMC 바로가기 [Article Type] Medicine
Satisfaction with life and psychological distress during the COVID-19 pandemic: An Egyptian online cross-sectional studyOriginal Research Published on 2022-01-312022-10-28 Journal: African Journal of Primary Health Care & Family Me [Category] Coronavirus, SARS, [키워드] adjusted odds ratio AOR Arabic being conducted Coronavirus disease 2019 COVID-19 COVID-19 pandemic cross-sectional distress Effect Egypt Evidence female highlight Impact independent predictor Intervention life Life satisfaction Mental mental illness moderate pandemic Prevalence promote provide Psychological distress Psychological well-being Result Satisfaction scale setting Sickness were measured [DOI] 10.4102/phcfm.v14i1.2896 PMC 바로가기 [Article Type] Original Research
Parental coronavirus disease vaccine hesitancy for children in Bangladesh: a cross-sectional studyResearch Article Published on 2022-01-252022-10-31 Journal: F1000Research [Category] COVID-19, [키워드] acute respiratory syndrome age analyzed Bangladesh children conducted coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 vaccine cross-sectional death developing countries Efficacy eligible Final Government higher odd identify immunization independent predictor Intention Intervention Logistic regression analysis parent parental parents pediatrics Prevalence questionnaire Randomly reported selected Sociodemographic characteristics Spread subgroup suggested Symptom vaccination Vaccine Vaccine hesitancy [DOI] 10.12688/f1000research.76181.1 PMC 바로가기 [Article Type] Research Article
Time-dependent evolution of IgG antibody levels after first and second dose of mRNA-based SARS-CoV-2 vaccination in haemodialysis patients: a multicentre study혈액 투석 환자에서 mRNA 기반 SARS-CoV-2 백신 1차 및 2차 접종 후 IgG 항체 수준의 시간 의존적 진화: 다기관 연구Multicenter Study Published on 2022-01-252022-09-12 Journal: Nephrology, dialysis, transplantation : official p [Category] SARS, 진단, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Adverse Adverse reaction age albumin antibody antibody production BNT162b2 Clinical data Cohort coronavirus coronavirus disease COVID-19 demographic dialysis dose effective Efficacy event Evolution ferritin first dose Haemodialysis higher risk identify IgG antibody immune response Immunoglobulin immunologic response implementation independent predictor median Mild mRNA vaccine mRNA vaccines mRNA-based multicentre Odds ratio of BNT162b2 pandemic Patient patients physical activity Population predicted questionnaire reduced Registered retrieved risk factor Safe SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 vaccination SARS-CoV-2 vaccine second dose Seroconversion Spike protein the SARS-CoV-2 threshold vaccination Vaccine vaccine doses [DOI] 10.1093/ndt/gfab293 PMC 바로가기 [Article Type] Multicenter Study
Non-communicable diseases (NCDs) and vulnerability to COVID-19: The case of adult patients with hypertension or diabetes mellitus in Gamo, Gofa, and South Omo zones in Southern EthiopiaResearch Article Published on 2022-01-252022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] 95% confidence interval adjusted odds ratio Analysis AOR association Community mobilization COVID COVID-19 COVID-19 pandemic COVID-19 virus cross-sectional determine diabete Diabetes Mellitus disease Evidence Fever form hypertension identify independent independent predictor independent variables individual infect infected individuals knowledge magnitude MDK monthly income Mortality objective outcome P-value Patient predicted question random regression analysis respiratory droplet Result significantly South Spread statistically significant Study design subject subjects subsequent was used zone [DOI] 10.1371/journal.pone.0262642 PMC 바로가기 [Article Type] Research Article
Evaluation of admission levels of P, E and L selectins as predictors for thrombosis in hospitalized COVID-19 patientsOriginal Article Published on 2022-01-212022-10-31 Journal: Clinical and experimental medicine [Category] COVID-19, MERS, 바이오마커, [키워드] Admission Anticoagulants Biomarker circulating clinical sensitivity Coagulopathy, P-selectin (CD62P) Complication controls coronavirus correlated COVID-19 COVID-19 patient COVID-19 patients death disease severity E-selectin E-selectin (CD62E) elevated ELISA endotheliopathy evaluate Factors feature healthy Hospital admission Hospitalization hospitalized COVID-19 patient identify independent predictor L-selectin (CD62L) laboratory biomarker P-selectin Patient platelets activation predict predicted predictor Prophylactic provided reported Retrospective study SARS-CoV-2 sensitivity significantly higher thrombosis [DOI] 10.1007/s10238-021-00787-9 PMC 바로가기 [Article Type] Original Article
The Role of Von Willebrand Factor in the Pathogenesis of Pulmonary Vascular Thrombosis in COVID-19Article Published on 2022-01-212022-10-28 Journal: Viruses [Category] COVID-19, [키워드] ARDS Bacterial correlation COVID-19 demonstrated died disease disease severity Duration endothelial Endothelium Factor histological immunostaining independent independent predictor intensity lung Mortality nonsurvivor Pathogenesis Patient patients with COVID-19 performed plasma Pneumonia pulmonary Pulmonary embolism reported role SARS-CoV-2 significant increase significantly more staining intensity the disease the patient thrombosis thrombotic complication Thrombotic complications thrombus formation Vascular endothelium Ventilation venular vessels von Willebrand factor vWF [DOI] 10.3390/v14020211 PMC 바로가기 [Article Type] Article
The Prognostic Role of Metabolic and Endocrine Parameters for the Clinical Severity of COVID-19COVID-19의 임상 중증도에 대한 대사 및 내분비 매개변수의 예후 역할Research Article Published on 2022-01-202022-09-10 Journal: Disease Markers [Category] 바이오마커, 진단, [키워드] Admission albumin blood cell blood count blood glucose C-reactive protein calcium clinical clinical study complete blood count coronavirus coronavirus disease Coronavirus disease-19 cortisol count COVID-19 COVID-19 patients creatinine Critical Critical illness cross-sectional duration of hospitalization Endocrine enrolled estimation Glucose Hormones ICU admission rates independent predictor independent predictors intensive care International laboratory result Laboratory results Lactate lactate dehydrogenase liver enzymes Magnesium material metabolic morbidity and mortality Mortality mortality rate Multivariate analysis nonsurvivor nonsurvivors objective outbreak outcome parameter Patient patients with COVID-19 phosphate poor prognosis profiles Prognosis Prognostic factor Prognostic factors public health emergency Recognition Result risk risk factor Risk factors role Serum level serum levels severe COVID-19 severity and prognosis significantly higher Spread survivor Thyroid Thyroid hormones Univariate analysis Vitamin D WBC WBC count were recorded White blood cell [DOI] 10.1155/2022/5106342 PMC 바로가기 [Article Type] Research Article
Hyperglycemia and Angiotensin-Converting Enzyme 2 in Pulmonary Function in the Context of SARS-CoV-2 InfectionMedicine Published on 2022-01-132022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 ACE2 glycation acute respiratory distress acute respiratory syndrome angiotensin-converting enzyme 2 China Comorbidity Complication Context coronavirus coronavirus disease COVID-19 Critical death Diabetes Mellitus Evidence function higher risk hyperglycemia hypothese incidence independent predictor information investigated Mortality multiple study non-enzymatic glycation pandemic pathophysiological mechanism Patient patients patients with COVID-19 prevalence of COVID-19 Prognosis Protein pulmonary reaction receptor SARS-CoV SARS-CoV-2 SARS-COV-2 infection shown syndrome with COVID-19 worse prognosis [DOI] 10.3389/fmed.2021.758414 PMC 바로가기 [Article Type] Medicine