Results of the Second Phase of the GER-e-TEC Experiment concerning the Telemonitoring of Elderly Patients Affected by COVID-19 Disease to Detect the Exacerbation of Geriatric SyndromesArticle Published on 2021-10-292022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] affected age alerts Analysis average Care concerning conducted coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 disease death decompensated heart failure deteriorate Deterioration died disorder elderly Elderly patient elderly patients Exacerbation experiment France Gender general condition geriatric syndromes global public health Health Hospital stay Hospitalization hospitalized patients MyPredi platform not affected pandemic Patient per day phase positive Predictive Result risk second sensitivity syndrome Telemonitoring the epidemic the mean took place university were recorded [DOI] 10.3390/jpm11111117 PMC 바로가기 [Article Type] Article
IFNL4 genetic variant can predispose to COVID-19IFNL4 유전자 변이체는 Covid-19를 유리하게 할 수 있습니다Article Published on 2021-10-272022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료법, [키워드] 95% CI age allele antiviral activity caused clearance confirmation contribute Control Coronaviruses COVID-19 COVID-19 patient disease disease severity General population Genetic association study Genetic variant genetic variants Genotype IFNL4 Infectious disease Infectious diseases Interferon lambda investigated mechanism not affected other infectious diseases overexpressed patients with COVID-19 polymorphism Predictive risk factor RNA viruses SARS-CoV-2 SARS-COV-2 infection Sex shown significantly lower T allele viral infection with COVID-19 [DOI] 10.1038/s41598-021-00747-z PMC 바로가기 [Article Type] Article
Development, implementation and feedback for an online speciality membership examination in orthodontics during the COVID-19 pandemicEducation Published on 2021-10-222022-10-27 Journal: British dental journal [Category] Coronavirus, Fulltext, MERS, SARS, [키워드] candidate categorise Cohort collected college COVID-19 pandemic demonstrated development domain eight elicited England examiner Google highlight implementation knowledge majority not affect not affected offer online delivery Orthodontics Part physician positive progression receive reflected reliability remote reported response responses Result social distancing Validity was used [DOI] 10.1038/s41415-021-3535-5 PMC 바로가기 [Article Type] Education
Vapourized hydrogen peroxide decontamination in a hospital setting inactivates SARS-CoV-2 and HCoV-229E without compromising filtration efficiency of unexpired N95 respirators병원 환경에서 기화된 과산화수소 오염 제거는 만료되지 않은 N95 호흡기의 여과 효율을 손상시키지 않으면서 SARS-CoV-2 및 HCoV-229E를 비활성화합니다.Article Published on 2021-10-012022-09-11 Journal: American journal of infection control [Category] SARS, 치료기술, [키워드] approach coronavirus COVID-19 COVID-19 pandemic decontamination determine effective Efficiency filtration for disinfection HCoV HCoV-229E hospital hydrogen hydrogen peroxide Hydrogen peroxide vapor investigated Mask Mask reprocessing N95 N95 respirator not affected reduced replicate Respirator respiratory Respiratory protection retained reuse SARS-CoV-2 SARS-CoV-2 virus Sterilization surrogate treated Treatment Viable viral burden virus was determined was tested [DOI] 10.1016/j.ajic.2021.07.012 PMC 바로가기 [Article Type] Article
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patientsResearch article Published on 2021-10-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] SARS, 바이오마커, [키워드] ACE2angiotensin-converting enzyme 2 ACEangiotensin-converting enzyme ACEiangiotensin-converting enzyme inhibitors Acute kidney injury affected age AKIAcute Kidney Injury Analysis Angangiotensin angiotensin Angiotensin receptor blockers Angiotensin-converting enzyme angiotensin-converting enzyme 2 angiotensin-converting enzyme inhibitors ARBangiotensin receptor blockers association BMI Clinical outcome Comorbidity Control Coronavirus disease 2019 corticosteroid treatment COVID-19 COVID-19 group COVID-19 mortality COVID-19 patient COVID-19 patients COVID-19coronavirus disease 2019 diabetes Hospital admission Hospitalization hypertension hypertensive COVID-19 patient ICU In-hospital death inhibitors of the renin-angiotensin system iRAAsinhibitors of the renin-angiotensin system lung Manifestations Matrix Metalloproteinase 2 Matrix Metalloproteinase 9 metalloproteinase metalloproteinases MMP-2Matrix Metalloproteinase 2 MMP-9Matrix Metalloproteinase 9 MMPsmetalloproteinases Mortality not affected obesity pathophysiologic Patient patients with COVID-19 plasma predicted predictor prognostic RASRenin-angiotensin system renin-angiotensin system respiratory risk SAPS3Simplified Acute Physiology Score III SARS-CoV-2severe acute respiratory syndrome coronavirus 2 sequential organ failure assessment score severe acute respiratory syndrome coronavirus 2 severe COVID-19 Sex Simplified Acute Physiology Score III SOFA score SOFAsequential organ failure assessment score study group survival Symptom treated were measured [DOI] 10.1016/j.biopha.2021.112067 [Article Type] Research article
Evaluation of adalimumab effects in managing severe cases of COVID-19: A randomized controlled trial중증 COVID-19 사례 관리에 대한 아달리무맙 효과 평가: 무작위 대조 시험Clinical Trial Published on 2021-10-012022-09-11 Journal: International immunopharmacology [Category] 임상, 진단, 치료제, [키워드] adalimumab assigned association caused change Combination combination therapy comparison Comparisons control group coronavirus COVID-19 COVID-19 cases Dexamethasone disease dose Effect group hospital ICU information intensive care unit Intervention intervention group mechanical ventilation Mortality mortality rate no significant difference not affected P-value Patient Pneumonia pulmonary Pulmonary infection radiologic Randomized controlled trial Remdesivir rising SARS-CoV-2 virus Severe case severe COVID-19 Spread Support supportive care the SARS-CoV-2 virus therapeutic therapeutic agent TNF-α treating COVID-19 Treatment two group two groups was used [DOI] 10.1016/j.intimp.2021.107961 PMC 바로가기 [Article Type] Clinical Trial
Soluble angiotensin-converting enzyme 2 is transiently elevated in COVID-19 and correlates with specific inflammatory and endothelial markers가용성 안지오텐신 전환 효소 2는 COVID-19에서 일시적으로 상승하고 특정 염증 및 내피 표지자와 상관관계가 있습니다Article Published on 2021-10-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 바이오마커, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 cell type cell types consequence coronavirus coronavirus disease Coronavirus disease 2019 correlated correlation correlations COVID-19 COVID-19 patient D-dimer disease severity ectodomain elevated Endothelial dysfunction endothelial marker enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay factor VIII Follow-up healthy controls healthy controls; infected cells Inflammation Inflammatory Inflammatory marker inflammatory markers inhibitor Interaction interleukin interleukin 6 interquartile range investigated Level main entry receptor marker median men Necrosis not affected not differ outcome pathology patients remained Renin renin angiotensin system renin-angiotensin system respiratory risk factor sACE2 SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe COVID-19 soluble ACE2 survival Tumor tumor necrosis tumor necrosis factor tumor necrosis factor α vascular beds von Willebrand factor women [DOI] 10.1002/jmv.27144 PMC 바로가기 [Article Type] Article
Analysis of the Role of N-Linked Glycosylation in Cell Surface Expression, Function, and Binding Properties of SARS-CoV-2 Receptor ACE2Research Article Published on 2021-09-082022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, MERS, SARS, [키워드] ACE2 ACE2 glycoprotein ACE2 receptor ACE2-spike binding addition antiviral therapy approach binding biological activities Cell cell entry receptor cell membrane coronavirus Critical demonstrated disrupt Endoplasmic reticulum enzyme examined expression function glycosylation hACE2 Human human ACE2 illness implicated Infection Interaction Mutagenesis N-glycan N-glycosylation N-linked glycan not affected offer property Protein Pseudotyped viruses receptor recruitment reduced reducing required role S proteins SARS Coronavirus SARS-CoV SARS-CoV S protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 S SARS-CoV-2 S protein subsequent Support surface susceptibility syncytium formation transmembrane glycoprotein Treatment type I understanding viral entry viral spike virus entry [DOI] 10.1128/Spectrum.01199-21 PMC 바로가기 [Article Type] Research Article
Semen parameters in men recovered from COVID-19COVID-19에서 회복된 남성의 정액 매개변수Article Published on 2021-09-012022-09-11 Journal: Asian journal of andrology [Category] SARS, 치료기술, [키워드] Adverse alteration analyzed Concentration consequence Control controls coronavirus disease COVID-19 ejaculate examined Health higher risk hospital discharge longitudinal analysis male median time men morphologically morphology not affected Novel coronavirus novel coronavirus disease pandemic parameter Patient patients percentage percentages progesterone recruited Semen serum Sex sex hormone Sex hormones significantly increased significantly lower Sperm sperm count sperm motility spermatogenesis spermatozoa suffered the patient time interval was obtained was reduced women [DOI] 10.4103/aja.aja_31_21 PMC 바로가기 [Article Type] Article
SARS-CoV-2 antibody dynamics and B-cell memory response over time in COVID-19 convalescent subjectsCOVID-19 회복기 대상에서 시간 경과에 따른 SARS-CoV-2 항체 역학 및 B 세포 기억 반응Article Published on 2021-09-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] SARS, 진단, [키워드] acute respiratory syndrome age Analysis anti-SARS-CoV-2 IgG antibody asymptomatic COVID-19 subject B-cell Blood blood sample clinical variable Cohort collected convalescent coronavirus coronavirus disease COVID-19 COVID-19 infection develop domain ELISA evaluate evaluated Gender healthy subject highlight humoral Humoral immunity IgG IgG antibody Infection majority memory B cell memory B-cell Memory B-cells memory response Mild nine no correlation not affected not differ over post infection Protective Randomly Rate recovering from COVID-19 reversed SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG antibody SARS-CoV-2 spike-specific selected severe disease spike IgG Spread subject subjects Time-related humoral response. undetectable was performed [DOI] 10.1016/j.cmi.2021.05.008 PMC 바로가기 [Article Type] Article