peripheral – Page 5 – Communicable Diseases Research

Paralysie faciale périphérique post-vaccination COVID-19: à propos d’un cas

Case Report

Published on 2021-12-212022-10-28
Journal: The Pan African Medical Journal [Category] COVID-19, SARS,

Modulatory Effects of Physical Activity Levels on Immune Responses and General Clinical Functions in Adult Patients with Mild to Moderate SARS-CoV-2 Infections—A Protocol for an Observational Prospective Follow-Up Investigation: Fit-COVID-19 Study

Protocol

Published on 2021-12-162022-10-04
Journal: International Journal of Environmental Research an [Category] SARS, 임상,

[키워드] activity Adipose tissue analyzed approach baseline Biochemistry Blood blood sample body composition clinical collected conducted Control coronavirus coronavirus disease COVID-19 cytokine profile determine Effect evaluated Evidence exercise Exercise capacity explain expressed function functional healthy help homologous immune Immunity immunomodulatory in-vitro assay inactive individual Infection Inflammation Inflammatory information innate immune system knowledge Level long-COVID mechanism Mental mental health metabolic parameters metabolism Mild Moderate COVID-19 mononuclear cell obese participant Patient patients with COVID-19 PBMC PBMCs peripheral phenotypic physical physical activity physical activity level physically positive procedure Prospective prospective observational cohort provided Pulmonary function registry repeated-measures ANOVA Respiratory muscle strength respond response SARS-CoV-2 SARS-COV-2 infection Seahorse serum stimulated survival the SARS-CoV-2 virus the vaccine Trajectories treated vaccination venous viral infection virus
[DOI] 10.3390/ijerph182413249 PMC 바로가기 [Article Type] Protocol

Peripheral Blood Mitochondrial DNA Levels Were Modulated by SARS-CoV-2 Infection Severity and Its Lessening Was Associated With Mortality Among Hospitalized Patients With COVID-19

Cellular and Infection Microbiology

Published on 2021-12-162022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, SARS,

sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity

STREM-1은 COVID-19 환자의 질병 중증도 및 사망률을 예측합니다 : 말초 혈액 백혈구 및 MMP-8 활동의 관여

Article

Published on 2021-12-152022-08-31
Journal: Viruses [Category] SARS, 바이오마커,

[키워드] activity Biomarker Characteristics clinical Clinical data coronavirus coronavirus disease correlated COVID-19 COVID-19 positive patient Critical death disease enrolled evaluated expressed expression groups IL-10 IL-6 IL-8 immunoassays indicated Inflammation inflammatory mediator inflammatory parameters Inflammatory response inflammatory signals intrinsic investigated Involvement lymphocyte lymphocyte counts matrix metalloproteinase matrix metalloproteinases mediator medical records Mild MMP-8 moderate Mortality MOST myeloid cells myeloid cells-1 neutrophil neutrophil counts outcome Patient patients with COVID-19 peripheral Peripheral blood peripheral blood cells pharmacological intervention pharmacological interventions plasma Plasma level Plasma levels positive correlation positive patients Predictive profile quantification severe disease severity severity of COVID-19 significant negative correlation significantly significantly higher sTREM-1 systemic the timing uncontrolled was related
[DOI] 10.3390/v13122521 PMC 바로가기 [Article Type] Article

Characteristics of peripheral white blood cells in COVID-19 patients revealed by a retrospective cohort study

Research

Published on 2021-12-092022-10-28
Journal: BMC Infectious Diseases [Category] COVID-19, SARS,

[키워드] analyzed association basophil branch changes in China city COVID-19 COVID-19 patient COVID-19 patients death died discharged eosinophil eosinophils glucocorticoid hematological Hematological change hospitalized COVID-19 patient immune response investigated Level lymphocyte Lymphocytes New non-survivor outcome Patient patients peripheral poor prognosis positive correlation predictor Prognosis proportion recruited Result retrospective cohort study SARS-COV-2 infection severe COVID-19 patient significantly lower subgroup analysis supplementary material survivor Survivors Tongji Hospital Treatment was performed White blood cell with COVID-19 Wuhan
[DOI] 10.1186/s12879-021-06899-7 PMC 바로가기 [Article Type] Research

Regulatory T Cells as Predictors of Clinical Course in Hospitalised COVID-19 Patients

입원한 COVID-19 환자의 임상 경과를 예측하는 조절 T 세포

Immunology

Published on 2021-12-022022-09-11
Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 진단,

[키워드] affected aggravation an area Analysis association AUC baseline CD4 circulating circulating cell clinical clinical evolution Clinical severity Combination correlated COVID-19 COVID-19 severity described Disease progression disease severity dysfunction dysregulation FiO2 flow cytometry Gender Hospital admission Hospitalization Host immune response hyper-inflammation identify immunophenotype inflammation markers lymphocyte lymphopenia management outcome PaO2 PaO2/FiO2 ratio parameter Patient Patient management performed peripheral Peripheral blood Phenotypic analysis predict presenting Probability progression reduced Regression analyses Regulatory Regulatory T cell regulatory T cells respiratory capacity Result risk ROC Curve SARS-COV-2 infection severe COVID-19 severe disease severity severity of COVID-19 shown significantly significantly higher Stratification subpopulation Support T cell T cell dysregulation T cell subset T cell subtypes T cells Th1 Ventilation WHO worsened worsening
[DOI] 10.3389/fimmu.2021.789735 PMC 바로가기 [Article Type] Immunology

Peripheral oxygen saturation to inspiratory oxygen fraction ratio-based identification of critically ill coronavirus disease patients for early therapeutic interventions

Observational Study

Published on 2021-12-012022-10-05
Journal: Journal of anesthesia [Category] SARS, 임상,

[키워드] Admission age albumin Antiviral assist blood test C-reactive protein Characteristics clinical setting clinician conducted coronavirus disease COVID-19 COVID-19 severity Critically ill D-dimer determine diagnosed with COVID-19 died Early identification examined extracorporeal membrane oxygenation fraction groups interquartile range invasive Japan Kyoto laboratory data lactate dehydrogenase Mild moderate mortality rate outcome oxygen oxygen saturation Patient peripheral positive pressure ventilation reducing renal replacement therapy respiratory rate retrospective severe COVID-19 severity SF ratio significantly lower single-center SpO2/FiO2 SpO2/FiO2. the patient therapeutic intervention therapeutic interventions turn two group university
[DOI] 10.1007/s00540-021-02986-w PMC 바로가기 [Article Type] Observational Study

Dynamic Changes in Central and Peripheral Neuro-Injury vs. Neuroprotective Serum Markers in COVID-19 Are Modulated by Different Types of Anti-Viral Treatments but Do Not Affect the Incidence of Late and Early Strokes

Article

Published on 2021-11-292022-10-28
Journal: Biomedicines [Category] COVID-19,

[키워드] 105 patient acute phase Admission Affect amyloid baseline level CCL23 change changes in Cluster clusterin collected conditions convalescent plasma correlated COVID-19 CRP D-dimer declined demonstrated diagnosis of COVID-19 dynamic elevated Elevation fetuin heterogeneity Hospitalized IL-6 incidence Inflammatory response initial KLK6 lack leukopenia marker MCP-1 MIF neurodegeneration neurodegenerative Neuroinflammation neurological nonspecific opposite outcomes Patient peripheral Platelet Proteins Registered remained Remdesivir response serum Serum level Serum Marker significantly Spike protein Steroids stroke therapy Treatment Type variable viral burden was increased YKL-40
[DOI] 10.3390/biomedicines9121791 PMC 바로가기 [Article Type] Article

CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab

CCR5 수용체 점유 분석 결과 항-CCR5 항체 레론리맙 치료 후 말초혈액 CCR5+CD4+ T 세포 증가

Clinical Trial

Published on 2021-11-192022-09-12
Journal: Frontiers in Immunology [Category] 임상, 진단,

[키워드] antibody assays binding blockade Blood cancer progression CCR5 CD4 CD4+ T cell CD4+ T cells Cell circulating comparable Complete correlated Critical Defense Efficacy facilitate flow cytometric flow cytometry HIV Host Human humans immunological Impact in vivo increase in Increased independent Infectious disease lack macaque macaques Occupancy pathophysiological peripheral Peripheral blood plasma plasma concentration Receptor occupancy receptor occupancy (RO) resulting sensitivity statistically significant suppressed T cell therapeutic Treatment viral replication Viremia Weekly with HIV
[DOI] 10.3389/fimmu.2021.794638 PMC 바로가기 [Article Type] Clinical Trial

Detection of Antibodies Against the SARS-CoV-2 Spike Protein and Analysis of the Peripheral Blood Mononuclear Cell Transcriptomic Profile, 15 Years After Recovery From SARS

SARS-CoV-2 스파이크 단백질에 대한 항체 검출 및 SARS 회복 15년 후의 말초혈액 단핵세포 전사체 프로파일 분석

Cellular and Infection Microbiology

Published on 2021-11-182022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus Against antibodies antibody binding cellular entry cellular immunity chemiluminescence chemokine clinical manifestations collected conducted convalescent patient Convalescent patients coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-reactivity cytokine detection elicit epitope Epitopes exhibited expressed Genes heatmap homology immune immune cross-reactivity Immune status Immunity immunoassay in vitro inhibit interferon gamma microsphere mononuclear cell mRNA mRNAs pandemic patients with COVID-19 patients with SARS PBMC PBMCs peptide peptide epitope peripheral Peripheral blood Peripheral blood mononuclear cells Post-infection profile protein sequences Research respiratory responses SARS-CoV SARS-CoV-2 SARS-CoV-2 spike protein serum serum antibodies severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Signal transduction significantly spike Spike protein stimulated the SARS-CoV-2 transcriptomic profile was obtained were used Year
[DOI] 10.3389/fcimb.2021.768993 PMC 바로가기 [Article Type] Cellular and Infection Microbiology