pro-inflammatory cytokine – Page 5 – Communicable Diseases Research

Markers of endothelial cell activation are associated with the severity of pulmonary disease in COVID-19

내피 세포 활성화의 마커는 COVID-19에서 폐 질환의 중증도와 관련이 있습니다

Article

Published on 2022-05-192022-09-11
Journal: PLoS ONE [Category] 바이오마커,

Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm

Famotidine은 미주 신경 염증 반사를 활성화하여 사이토카인 폭풍을 약화시킵니다.

Article

Published on 2022-05-162022-09-11
Journal: Molecular Medicine [Category] 유전자 메커니즘,

[키워드] Acetylcholine acetylcholine receptor activate Administered Alpha antagonist Anti-inflammatory anti-inflammatory activity anti-inflammatory effect Anti-inflammatory effects antiviral activity attenuate Blood brain barrier Brain cause Central nervous system characterized cholinergic Cholinergic anti-inflammatory pathway Cimetidine Clinical course Clinical studies clinical study Clinical use concentrations COVID-19 Cytokine storm disease dosage dosages Effect Evidence Famotidine Gastroesophageal reflux gastroesophageal reflux disease Genetic Histamine Histamine receptors ICV IL-6 Inflammatory inhibits inflammation knock-out lipopolysaccharide mast cell Mast cells mechanism mechanism of action mice morbidity and mortality Necrosis observation penetrate Prevent pro-inflammatory cytokine pro-inflammatory cytokine release Ranitidine recent receptor reduced released replicated serum severe COVID-19 Signal transduction Signaling significantly significantly more stimulated survival syndrome TNF treat Tumor tumor necrosis tumor necrosis factor vagus nerve Vagus nerve signaling. were assessed while α7nAChR
[DOI] 10.1186/s10020-022-00483-8 PMC 바로가기 [Article Type] Article

Evaluation of patients with telogen effluvium during the pandemic: May the monocytes be responsible for post COVID-19 telogen effluvium?

Observational Study

Published on 2022-05-012022-10-04
Journal: Journal of cosmetic dermatology [Category] COVID19(2023년), SARS, 임상,

[키워드] cause circulating monocyte Clinical characteristics conducted coronavirus disease COVID-19 COVID-19 diagnosis COVID-19-related complications demographic develop diagnosed with COVID-19 Diagnosis electronic medical records evaluate hair follicle hair follicles Hair loss incidence IQR laboratory parameter Macrophage mechanism mechanisms median Migration monocyte Monocytes Observational cohort study occurred pandemic Patient patients Peripheral blood Physical examination polymerase chain pro-inflammatory cytokine reported responsible RT-PCR SARS-CoV-2 suggested telogen effluvium the patient triggering factor was performed were recorded
[DOI] 10.1111/jocd.14883 PMC 바로가기 [Article Type] Observational Study

Immunomodulatory effects of zinc and its impact on COVID-19 severity

Short communication

Published on 2022-05-012022-10-05
Journal: Annals of Medicine and Surgery [Category] 변종, 임상, 진단,

Can Panax ginseng help control cytokine storm in COVID-19?

Review article

Published on 2022-05-012022-10-05
Journal: Journal of Ginseng Research [Category] 치료제,

CSF Biomarkers in COVID-19 Associated Encephalopathy and Encephalitis Predict Long-Term Outcome

COVID-19 관련 뇌병증 및 뇌염의 CSF 바이오마커는 장기적인 결과를 예측합니다

Article

Published on 2022-04-112022-09-11
Journal: Frontiers in Immunology [Category] Coronavirus, COVID19(2023년), SARS, 바이오마커,

[키워드] activity acute COVID-19 antibodies antibody Antigen antigens Autoimmunity blood-brain barrier both groups Complication coronavirus disease Coronavirus disease 2019 correlated COVID-19 CSF cytokine cytokine profile Cytokine storm syndrome Cytokines develop diagnostic elevated Encephalitis Encephalopathy evaluate Follow-up functional group healthy control healthy controls Hospitalized IgG IL-10 IL-18 IL-1ra IL-6 IL-8 in both groups include Inflammation Inflammatory Inflammatory cytokines inflammatory process IP-10 manifestation MCP1 MIG neuro-COVID neurofilaments neurologic Neurological involvement neuronal neuronal antibodies. no difference no differences outcome Patient patients predict pro-inflammatory cytokine pro-inflammatory cytokines Prognosis prognostic Proinflammatory cytokine proinflammatory cytokines promoted Protein SARS-CoV-2 SARS-COV-2 infection serum serum biomarker serum biomarkers severity significantly viral-induced while
[DOI] 10.3389/fimmu.2022.866153 PMC 바로가기 [Article Type] Article

The Importance of Nutraceuticals in COVID-19: What’s the Role of Resveratrol?

COVID-19에서 기능식품의 중요성: 레스베라트롤의 역할은 무엇입니까?

Review

Published on 2022-04-072022-09-11
Journal: Molecules [Category] 치료제,

[키워드] acting adjuvant affected aggressiveness anti-inflammatory agent anti-inflammatory properties antiviral activity autophagy Cell characteristic concerning COVID-19 COVID-19 patients Cytokines decrease effective expression global public health immune Immune cell immune system Immunity immunomodulating Importance IMPROVE increase Infection infections Inflammation information inhibiting limit mechanisms Mortality Multiorgan dysfunction nutraceutical occur pathophysiology Patient Prevent pro-inflammatory pro-inflammatory cytokine pro-inflammatory cytokines regulate resveratrol risk role solution the disease therapy thrombotic thrombotic event Thrombotic events urgency viral replication virus
[DOI] 10.3390/molecules27082376 PMC 바로가기 [Article Type] Review

Regulation of Proinflammatory Molecules and Tissue Factor by SARS-CoV-2 Spike Protein in Human Placental Cells: Implications for SARS-CoV-2 Pathogenesis in Pregnant Women

인간 태반 세포에서 SARS-CoV-2 스파이크 단백질에 의한 전염증성 분자 및 조직 인자의 조절: 임산부의 SARS-CoV-2 발병에 대한 의미

Article

Published on 2022-04-072022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술,

[키워드] ACE2 binding CCL2 CCL5 Cell cell line chemokine chemokines coagulation cascade complications contribute CTBs CXCL10 CXCL9 cytokine Cytokine storm Cytokines dysfunction elevate elevated ELISA Endothelial cell endothelial cells Express expression extrinsic Factor first trimester FUSE host cells Human IL-6 IL-8 immunohistochemical staining immunoreactivity Impaired pregnancy indicated induce infect Infection molecule outcomes Placenta placental placental dysfunction placental thrombosis pregnancies Pregnancy pregnancy complications pregnant women pro-inflammatory cytokine pro-inflammatory cytokine release pro-inflammatory cytokines proinflammatory Proinflammatory cytokine proinflammatory cytokines qPCR S-protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein secreted significantly higher specimen spike Spike protein stromal cell stromal cells syncytiotrophoblast term the cytokine storm thrombosis tissue Tissue Factor TMPRSS2 TMPRSS2 level TMPRSS2 levels treated trophoblast Viral RNA virus was measured was performed were measured
[DOI] 10.3389/fimmu.2022.876555 PMC 바로가기 [Article Type] Article

In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release

미세혈관 내피 세포의 시험관 내 SARS-CoV-2 감염: 염증성 사이토카인 및 케모카인 방출에 대한 영향

Article

Published on 2022-04-062022-09-11
Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 치료기술,

[키워드] ACE2 receptor Activation Analysis chemokine contribute coronavirus disease Coronavirus disease 2019 cytokine release Cytokines cytoplasm days post-infection dysfunction Effect electron ELISA endothelial Endothelial cell evaluated expressed expression Human Human Microvascular Endothelial Cells (HMEC-1) IFN-α IL-6 IL-6 level IL-6 levels IL-8 in vitro Inflammatory mediators mRNA mRNA expression pandemic pro-inflammatory cytokine pro-inflammatory cytokines pro-inflammatory mediators Release RT-PCR SARS-CoV-2 SARS-COV-2 infection significantly higher significantly lower supernatant supernatants susceptible TEM These data thrombotic Thrombotic events tissue Tissue Factor TNF-α transmission electron microscopy uninfected viral amplification Viral load virion virions western blot Western blot analysis
[DOI] 10.3390/ijms23074063 PMC 바로가기 [Article Type] Article

Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression

Research article

Published on 2022-04-012022-10-05
Journal: Heliyon [Category] 바이오마커, 진단,