SARS-CoV-2 spike protein antibody titers 6 months after SARS-CoV-2 mRNA vaccination among patients undergoing hemodialysis in JapanArticle Published on 2022-10-012022-11-15 Journal: Clinical and experimental nephrology [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome anti-SARS-CoV-2 spike protein antibody Antibody titer Antibody titers BNT162b2 calculated clinics conducted contributed controls coronavirus death dose FIVE HD group healthy control Hemodialysis immune response Japan linear log log-transformed Lower mixed-effects model mRNA vaccination mRNA vaccine Patient patients Pfizer-BioNTech Prevent Protein reduced remained Retrospective study S1 IgG SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein second dose second vaccination shown significantly significantly lower vaccination Vaccine were measured [DOI] 10.1007/s10157-022-02243-8 PMC 바로가기
Coronavirus disease 2019 (COVID-19)-related smell and taste impairment with widespread diffusion of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) Omicron variantArticle Published on 2022-10-012022-11-16 Journal: International forum of allergy & rhinology [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval Characteristics chemosensory clinical presentation coronavirus disease Coronavirus disease 2019 COVID-19 diffusion dropped dysfunction evaluated impairment Infection Mild-to-moderate olfactory olfactory dysfunction omicron Omicron variant outcomes Patient patients positive Prevalence Prospective reported SARS-CoV-2 sense of smell sense of taste severity significantly significantly lower Smell study cohort subject Taste taste dysfunction variant widespread [DOI] 10.1002/alr.22995 PMC 바로가기
Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccinationArticle Published on 2022-10-012022-11-16 Journal: RMD Open [Category] COVID19(2023년), SARS, 변종, [키워드] administration Arthritis booster booster vaccination control group COVID-19 COVID-19 vaccination demonstrated Epidemiology impairment medication methotrexate mRNA MTX neutralisation neutralising Observational cohort study occur omicron Patient Prevent pseudovirus neutralisation assay reached receiving SARS-CoV-2 serum significantly higher significantly lower therapy Treatment vaccination vaccine response variant variants were assessed while wild-type [DOI] 10.1136/rmdopen-2022-002639 PMC 바로가기
Characterization of serotonin as a candidate biomarker of severity and prognosis of COVID-19 using LC/MS analysisResearch article Published on 2022-10-012022-10-05 Journal: Journal of pharmacological sciences [Category] 바이오마커, 진단, [키워드] Analysis analyzed Biomarker characterization Concentration concentrations coronavirus disease COVID-19 COVID-19 severity diagnostic disease severity effective high mortality management moderate disease pandemic pathophysiology Patient patients with COVID-19 Prognosis prognostic biomarker Serotonin serum severe COVID-19 severe disease severity and prognosis significantly lower worsened [DOI] 10.1016/j.jphs.2022.06.005 [Article Type] Research article
Usefulness of the Legionella Score for differentiating from COVID-19 pneumonia to legionella pneumoniaResearch article Published on 2022-10-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] 진단, [키워드] analyzed Anosmia Bacterial C-reactive protein causative pathogen clinically community-acquired pneumonia cough COVID-19 COVID-19 pandemic demonstrated Diagnosis diagnostic groups investigated Japan Laboratory lactate dehydrogenase Legionella Legionella pneumophila Legionella score less Loss loss of taste median novel coronavirus disease parameter Patient patients with COVID-19 physician Pneumonia Psychiatric SARS-CoV-2 score scoring system significantly higher significantly lower Society sodium Symptom with COVID-19 [DOI] 10.1016/j.jiac.2022.06.012 [Article Type] Research article
Saliva for molecular detection of SARS-CoV-2 in pre-school and school-age childrenArticle Published on 2022-10-012022-11-15 Journal: Environmental microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Adults age asymptomatic subjects children collected comparable contrary coronavirus disease COVID-19 detection rate Diagnosis early stage independent Infection initial initial symptom invasive less management molecular nasopharyngeal NPs Numerous Patient performance RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 detection sensitivity serological seronegative significantly significantly lower Symptoms [DOI] 10.1111/1462-2920.16151 PMC 바로가기
“Lymphocyte * Neutrophil” count decreased in SARS-CoV-2 Omicron patients in Shanghai with no significant change in CRP and SAAArticle Published on 2022-10-012022-11-16 Journal: Journal of Clinical Laboratory Analysis [Category] COVID19(2023년), SARS, 변종, [키워드] all subject Analysis analyzed AUC Blood can be used CBC changes changes in Clinical data collected contrary correlated CRP cutoff value Diagnosis diagnostic differential diagnosis EOS excluded Fever had no in some inflammatory indicator lymphocyte neutrophil NLR not significantly different omicron Patient patients patients with SARS-CoV-2 PCT positive Previous studies prognosis of patients SAA SARS-CoV-2 selected Sensitivity and specificity Shanghai significantly significantly higher significantly lower the SARS-CoV-2 Toxicity variant was selected WBC while [DOI] 10.1002/jcla.24671 PMC 바로가기
The impact of COVID-19 restrictions on participant enrollment in the PREPARE trialResearch article Published on 2022-10-012022-10-05 Journal: Contemporary Clinical Trials Communications [Category] 임상, [키워드] affected approval clinical trials COVID-19 COVID-19 pandemic COVID-19 research Enrollment Evaluating extremities implementation interquartile range median pandemic participant Patient Pragmatic pragmatic trials PREPARE trial protocol recorded researcher Result significantly lower skin solution t-test Trial [DOI] 10.1016/j.conctc.2022.100973 [Article Type] Research article
Real-world effectiveness of early remdesivir and sotrovimab in the highest-risk COVID-19 outpatients during the Omicron surgeArticle Published on 2022-09-302022-11-15 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 진단, [키워드] 95% CI all-cause mortality B.1.1.529 clinical trial Cohort component control patient COVID-19 COVID-19 outpatient Effectiveness evaluate events Hospitalization Hospitalized incidence less likelihood no difference omicron Outpatient positive Primary outcome receive receiving reduction in Remdesivir retrospective cohort study risk SARS-CoV-2 secondary outcome severe COVID-19 significantly significantly lower Symptom symptom onset the primary endpoint therapy treated [DOI] 10.1093/jac/dkac256 PMC 바로가기
The changing spectrum of microbial aetiology of respiratory tract infections in hospitalized patients before and during the COVID-19 pandemicArticle Published on 2022-09-302022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] 95% CI Admission aetiology Bacteria Bacterial Bergen categorical data Cohort cohorts Community community acquired community acquired pneumonia conducted containment measures COVID COVID-19 COVID-19 pandemic declined Electronic health record Epidemiology FilmArray pneumonia panel Fisher Haemophilus influenzae hospital Hospital admission hospitalized patient infection control less Lower respiratory tract Mann-Whitney measure microbial molecular testing outbreak pathogen Patient patients Pneumonia proportion Prospective Study reducing respiratory respiratory tract infection Respiratory tract infections SARS-CoV-2 significantly lower specimens Spread Staphylococcus aureus Streptococcus pneumoniae surveillance data t-test Trust variables virus was used [DOI] 10.1186/s12879-022-07732-5 PMC 바로가기