COVID-19(15) Patient(13) severe COVID-19(13) reported(11) coronavirus disease(8) SARS-CoV-2(7) Biomarker(7) drug(7) Prognosis(7) prognostic biomarker(7) therapeutic agents(6) mechanism(6) Transient receptor potential channel.(6) acute respiratory syndrome coronavirus 2(6) Vaccine-resistant variants(6) Cancer(6) outcome(6) increase(6) heart failure(6) age(6) protein-protein interaction(6) Eco-pharma(6) acute respiratory syndrome(6) mammalian cells(6) Mortality(6) shown(6) hypertension(6) therapeutic(6) aggravation(6) Protein–protein interaction(6)