Rapid Evaluation of Coronavirus Illness Severity (RECOILS) in intensive care: Development and validation of a prognostic tool for in‐hospital mortalityResearch Article Published on 2021-10-152022-10-28 Journal: Acta Anaesthesiologica Scandinavica [Category] COVID-19, MERS, SARS, [키워드] admitted to ICU age AUROC average Blood urea nitrogen Cohort Corona virus COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 Critical care dataset determine develop development died hospital Hospital stay ICU ICU admission ICU patient ICUs illness Intensive intensive care ISARIC 4C literature review Logistic males mechanical ventilation Mortality multicenter multivariable model National PaCO2 PaO2/FiO2 ratio Patient Platelets Predictive prognostic Rapid reported resource Respiratory failure Result scale score SOFA temperature Treatment validation study variable was performed were used [DOI] 10.1111/aas.13991 PMC 바로가기 [Article Type] Research Article
Enterococcal bloodstream infections in critically ill patients with COVID-19: a case seriesResearch Article Published on 2021-10-122022-10-28 Journal: Annals of Medicine [Category] COVID-19, SARS, [키워드] 30-Day mortality 95% confidence interval association Blood bloodstream bloodstream infection BSI case sery caused Characteristics clinical conditions confidence interval contribute COVID-19 COVID-19 patient Critically ill Critically ill patient cumulative Enterococcus Enterococcus faecium ICU ICU admission in vitro activity incidence increased mortality independent Infection intensive care material Most patient Odds ratio Organ failure outcome Patient patients patients with COVID-19 predictor Prevalence Registered Result SARS-CoV-2 severity SOFA study period therapy Viral pneumonia VRE with COVID-19 [DOI] 10.1080/07853890.2021.1988695 PMC 바로가기 [Article Type] Research Article
Tracheostomy in patients with COVID-19: predictors and clinical featuresObservational Study Published on 2021-10-012022-10-05 Journal: European archives of oto-rhino-laryngology : offic [Category] SARS, 임상, [키워드] 95% CI Agitation assessment Cardiac arrhythmia Clinical course Clinical data clinical feature cohort study collected Complication complications COVID-19 Critical cut-off demographic Depression failure hospital ICU ICU admission identify increased risk mechanical ventilation Negative predictive value Nosocomial infection parameter Patient patients hospitalized patients with COVID-19 Positive predictive value predictor primary endpoint Prolonged Prolonged mechanical ventilation respiratory Respiratory failure secondary endpoint sensitivity SOFA specificity supraventricular Thromboembolism tracheostomy transferred [DOI] 10.1007/s00405-020-06555-x PMC 바로가기 [Article Type] Observational Study
mNUTRIC tool is capable to predict nutritional needs and mortality early in patients suffering from severe pneumoniaObservational Study Published on 2021-10-012022-10-05 Journal: Clinical nutrition ESPEN [Category] SARS, 임상, [키워드] 95% CI Accuracy Admission Analysis APACHE II AUC value base calculated Care Chest CT chronic COVID-19 CURB-65 died discharged evaluate highest Hospitalization Hospitalized IBM initiated intensive care Intensive care unıt mNUTRIC. Mortality NRS-2002 nutrition nutritional need Organ failure pandemic Patient patients patients hospitalized Physiology positive predict prognostic retrospective reverse transcription PCR RT-PCR RT-PCR test severe pneumonia SOFA SPSS Statistics the patient Treatment was performed while [DOI] 10.1016/j.clnesp.2021.08.030 PMC 바로가기 [Article Type] Observational Study
The COVID-19 Assessment for Survival at Admission (CASA) Index: A 12 Months Observational StudyMedicine Published on 2021-09-302022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age albumin assessment AUC Care clinician Coronavirus disease 2019 COVID-19 COVID-19 patient Critical cut-off D-dimer defined develop disease help high risk hospital Hospital admission in-hospital mortality intensity Month Mortality mortality rate mortality risk Negative predictive value outcome outcome research Patient Positive predictive value Pragmatic progression respiratory rate risk sensitivity Seven SOFA specificity Stratification stratification index systemic score to define variable White blood cell [DOI] 10.3389/fmed.2021.719976 PMC 바로가기 [Article Type] Medicine
Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in PakistanClinical Trial Published on 2021-09-272022-10-04 Journal: BMC Infectious Diseases [Category] SARS, 임상, [키워드] Analysis ANOVA applied can be used Chi-square clinical status Complication conducted Convalescent CP recipient convalescent plasma Convalescent plasma (CP) correlated COVID pneumonia COVID-19 COVID-19 pandemic COVID-19 patient criterion Critical critical cases Cytokine storm death disease Disease progression Endpoint Enrollment expired Fisher’s exact test FIVE hospitalized patients interquartile ranges invasive ventilation lung infiltrates lung infiltration Mann-Whitney U test median median age median time multiorgan failure non-randomized onset of symptom open label oxygen saturation parameter Patient patients potential therapy recipient recipients registration date Result Safe SARS CoV2 infection severe adverse events severe patients severity SOFA SOFA score SPSS Study design transfused Treatment Trial Trial registration ventilator [DOI] 10.1186/s12879-021-06451-7 PMC 바로가기 [Article Type] Clinical Trial
Racial disparities in the SOFA score among patients hospitalized with COVID-19Research Article Published on 2021-09-172022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] 24 hour 95%CI Admission age Analysis analyzed assessment black Black patient Black patients Care cohort study conducted consecutive patient COVID-19 pandemic dichotomized elevated excluded failure female greater Health Hispanic Hispanic patient hospital Hospitalized in-hospital mortality inclusion criteria Logistic medical resource multivariate model New Patient patients hospitalized predict Primary outcome Probability question recorded resource Result social determinant SOFA SOFA score System white White patient with COVID-19 [DOI] 10.1371/journal.pone.0257608 PMC 바로가기 [Article Type] Research Article
The potential impact of triage protocols on racial disparities in clinical outcomes among COVID-positive patients in a large academic healthcare systemResearch Article Published on 2021-09-162022-10-28 Journal: PLoS ONE [Category] Coronavirus, SARS, [키워드] age analyzed ANOVA association assumption black Black patient Care chi-square test Clinical outcome clinical outcomes COVID patient COVID-19 COVID-19 pandemic determine develop equity exacerbate examined Final greater group Healthcare system Hospitalized ICU admission in-hospital mortality linear Logistic regression Organ failure Other Patient patients populations predictor protocol protocols Racial resource resources Result retrospective cohort Sex significantly Sociodemographic characteristics SOFA SOFA score System The United States translate while [DOI] 10.1371/journal.pone.0256763 PMC 바로가기 [Article Type] Research Article
Clinical characteristics and risk factors of fatal patients with COVID-19: a retrospective cohort study in Wuhan, ChinaResearch Article Published on 2021-09-142022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] Accuracy addition age APACHE II Biomarker caused Characteristics clinical Clinical management Clinical prognosis Comorbidity Complication coronavirus disease COVID-19 COVID-19 patient death Death risk early stage elevated enrolled Factor global pandemic help hypoxia Immune cell Immune cells subsets Inflammatory cytokines Mortality multi-organ dysfunction Multiple organ damage non-survivor Patient potential risk predict Predictive predictor propensity score matching qSOFA Result resulting retrospective cohort study Retrospective study risk risk factor Risk factors Risk prediction models Sex significantly significantly higher SIRS SOFA subset supplementary material survivor Wuhan, China [DOI] 10.1186/s12879-021-06585-8 PMC 바로가기 [Article Type] Research Article
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial가용성 우로 키나제 플라스 미노 겐 수용체 혈장 수준에 의해 유도 된 아나키라로 Covid-19의 조기 치료 : 이중 맹검, 무작위 대조 3 상 시험Clinical Trial Published on 2021-09-032022-08-13 Journal: Nature Medicine [Category] MERS, SARS, 바이오마커, 임상, 치료법, [키워드] 11-point World Health Organization Clinical Progression Scale adjusted proportional odd adjusted proportional odds Anakinra assessment baseline clinical clinical status coronavirus disease Coronavirus disease 2019 COVID-19 decrease Dexamethasone double-blind Efficacy Efficacy and safety evaluated failure group hazard ratio Health Organization Hospital stay IL-1α/β IL-1α/β inhibitor increased risk median Mortality Odds ratio patients with COVID-19 phase 3 study phase 3 trial Placebo plasma plasma suPAR progression Randomized Randomized controlled trial receiving receptor Respiratory failure risk SAVE SAVE-MORE SAVE-MORE double-blind scale Serum level SOFA soluble urokinase plasminogen activator receptor suPAR Treatment WHO-CPS World Health Organization [DOI] 10.1038/s41591-021-01499-z PMC 바로가기 [Article Type] Clinical Trial