Global Health Partnerships During the COVID-19 Pandemic: Perspectives and Insights from International PartnersOriginal Research Paper Published on 2021-08-282022-10-28 Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, MERS, SARS, [키워드] analyzed conducted coronavirus disease COVID-19 COVID-19 pandemic cross-sectional facilitate global health Health identify impacted implication individual insight International MOST New organizations pandemic participant partner partnership performed Perspective positive provided reported the United State The United States transcribed United State were expressed [DOI] 10.4269/ajtmh.21-0156 PMC 바로가기 [Article Type] Original Research Paper
Development and clinical evaluation of a rapid antibody lateral flow assay for the diagnosis of SARS-CoV-2 infectionSARS-COV-2 감염의 진단을위한 빠른 항체 측면 흐름 분석의 발달 및 임상 평가Research Article Published on 2021-08-232022-09-01 Journal: BMC Infectious Diseases [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analytical sensitivity analyzed antibody Antibody test can be used caused clinic clinical Clinical application value clinical evaluation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19 patients cross-reactivity development Diagnosis diagnosis of SARS-CoV-2 disease course Escherichia coli evaluate expressed false-negative false-negative results Fever fragment of Health IgM antibody Infection Infectious disease lateral flow lateral flow assay limitations measure Mycoplasma pneumoniae N protein Novel coronavirus novel coronavirus disease nuclear Nurse Nurses outbreak Pathogens Patient pneumoniae positive rate professional Protein Pulmonary infection purified rapid antibody test rapid antibody test kit real-time PCR Kit Recombinant S1 protein respiratory Respiratory pathogens respiratory tract infection Result RT-PCR SARS-CoV-2 SARS-CoV-2 antibody test SARS-CoV-2 diagnosis SARS-COV-2 infection serum severe acute respiratory syndrome Coronavirus significantly specificity Spike protein Spread supplementary material were expressed [DOI] 10.1186/s12879-021-06568-9 PMC 바로가기 [Article Type] Research Article
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor binding domain (RBD) induces an enhanced and protective response in mice다량체화된 SARS-CoV-2 수용체 결합 도메인(RBD)을 사용한 단일 용량 면역은 마우스에서 강화된 보호 반응을 유도합니다Research Letter Published on 2021-08-222022-09-12 Journal: Febs Letters [Category] MERS, 진단, [키워드] Analysis Antibody titre Antigen antigens Bacteria buffer caused complexes coronavirus COVID‐19 COVID‐19 defined demonstrated Dps elicited exclusion experiment expressed form health emergency highlight immunisation increase induce introduced lung mammalian cells mice Microscopy monomeric RBD neutralising antibody pandemic Particle PBS preparation Protective purified Quality control RBD Receptor binding domain SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 SDS spike Subunit vaccine triggered Vaccine viral clearance were expressed [DOI] 10.1002/1873-3468.14171 PMC 바로가기 [Article Type] Research Letter
The aftermath of COVID-19 pandemic on the diagnosis of TB at a tertiary care hospital in IndiaResearch article Published on 2021-08-012022-10-05 Journal: Journal of infection and public health [Category] SARS, 진단, [키워드] analyzed Care categorical variable changed Chi-square conducted COVID-19 COVID-19 pandemic Culture Department Diagnosis diagnostic End TB Extra-pulmonary tuberculosis EZR Frequency global public health healthcare service highlight hospital Impact impacted increase in India indicated Microbiology Microscopy pandemic proportion pulmonary tuberculosis reduction Result resulting reveal South specimen statistical significance TB diagnostics Tuberculosis was performed were expressed [DOI] 10.1016/j.jiph.2021.07.001 [Article Type] Research article
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitroArticle Published on 2021-07-282022-10-04 Journal: Nature Communications [Category] SARS, 변종, [키워드] anti-viral activity antibody binding block Brain cells cofactor Coronaviruses dissemination Effect expression Gut human cell human lung human lung cells IFITM in vitro in vitro model in vivo Infection inhibit inhibit SARS-CoV-2 Innate immunity interact interferon organoids overexpression Pathogenesis peptide promote Protein Replication reported representing restrict SARS-CoV-2 SARS-COV-2 infection spike Support target the SARS-CoV-2 therapeutic approaches transmembrane protein viral infection viral pathogens Viral transmission virus entry virus inhibition viruses were expressed [DOI] 10.1038/s41467-021-24817-y PMC 바로가기 [Article Type] Article
A bivalent protein targeting glycans and HR1 domain in spike protein potently inhibited infection of SARS-CoV-2 and other human coronavirusesResearch Published on 2021-07-082022-11-01 Journal: Cell & Bioscience [Category] COVID-19, [키워드] Antiviral component conducted coronavirus COVID-19 Diseases E. coli effective EK1 ELISA evaluate exhibited expressing GL25E glycan GRFT HCoV-229E HCoV-NL63 HCoV-OC43 HIV HR1 domain human coronavirus in vitro in vivo Infection inhibit inhibited inhibiting inhibitory inhibitory activity intranasally mechanism of action MERS-CoV mice mutants mutated Newborn Ni-NTA peptide performed Prevent previous study Prophylactic protective effect Protein Proteins pseudovirus purified Result S protein S2 subunit SARS-CoV SARS-CoV-2 SARS-COV-2 infection selected shown significantly more Spike protein the S1 subunit therapeutic treat were expressed wild-type [DOI] 10.1186/s13578-021-00638-w PMC 바로가기 [Article Type] Research
The response of total testing process in clinical laboratory medicine to COVID-19 pandemicOriginal Articles Published on 2021-06-152022-10-27 Journal: Biochemia Medica [Category] COVID-19, [키워드] affected changes in COVID-19 evaluated Factors flexible Laboratory material pandemic percentage quality indicator Result sigma significantly higher significantly lower total testing process transported were assessed were expressed [DOI] 10.11613/BM.2021.020713 PMC 바로가기 [Article Type] Original Articles
The response of total testing process in clinical laboratory medicine to COVID-19 pandemicOriginal Articles Published on 2021-06-152022-10-27 Journal: Biochemia Medica [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] affected changes in COVID-19 evaluated Factors flexible Laboratory material pandemic percentage quality indicator Result sigma significantly higher significantly lower total testing process transported were assessed were expressed [DOI] 10.11613/BM.2021.020713 PMC 바로가기 [Article Type] Original Articles
Production of SARS-CoV-2 Virus-Like Particles in Insect CellsArticle Published on 2021-05-262022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] bacmid baculovirus cause Cell cloned competent COVID-19 disease Escherichia coli expression generate Health Infection insect insect cell insect cells morphology multiple cloning site Particle Plasmid platform Production promoter promoters S gene S protein SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 VLP virions virus-like particles VLPs were expressed [DOI] 10.3390/vaccines9060554 PMC 바로가기 [Article Type] Article
COVID-19 and Obesity: An Epidemiologic Analysis of the Brazilian DataResearch Article Published on 2021-05-052022-10-30 Journal: International Journal of Endocrinology [Category] COVID-19, [키워드] age Analysis analyzed Brazil categorical variable chi-square test Continuous country COVID-19 COVID-19 severity database death deaths Descriptive statistics diagnosed with COVID-19 died disease effective epidemiological data form Frequency highest increase intensive care invasive management median men Ministry of Health noninvasive nonparametric test obesity Older Patient patients hospitalized risk factor subject Support ventilatory support were expressed were used with COVID-19 worse prognosis [DOI] 10.1155/2021/6667135 PMC 바로가기 [Article Type] Research Article