Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020Research Published on 2020-10-222022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome antibody Blood blood donor can be used collected Control coronavirus COVID19 demonstrated detect detection determine diagnosed Donor Epidemic geographical distribution Infection marker microneutralisation assay neutralising antibody number of sample outbreak pandemic performed progression pseudotyped SARS-CoV-2 virus remained Result SARS-CoV-2 Scottish sera serological serology Serosurvey significantly surveillance, Scotland symptomatic individual the epidemic the SARS-CoV-2 United Kingdom was used [DOI] 10.2807/1560-7917.ES.2020.25.42.2000685 PMC 바로가기 [Article Type] Research
Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic IndividualsMicrobiology Published on 2020-10-192022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] anti-N antibody anti-RBD anti-S2 anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody asymptomatic individual asymptomatic patients Convalescent plasma therapy COVID-19 declined detectable evaluate help immune response in-house ELISAs individual induce infected patients Inpatient majority Neutralizing antibodies neutralizing antibody Neutralizing antibody response nucleocapsid Particle post-symptom onset predict pseudotyped RBD reached Reinfection retroviral SARS-CoV-2 Seroconversion serological Serological assay seropositive shown specific antibody spike subunits the SARS-CoV-2 undetectable Vaccine Vaccines [DOI] 10.3389/fmicb.2020.584251 PMC 바로가기 [Article Type] Microbiology
Capillary whole-blood IgG-IgM COVID-19 self-test as a serological screening tool for SARS-CoV-2 infection adapted to the general publicResearch Article Published on 2020-10-152022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] All participant asked capillary coded Complete conditioned COVID-19 COVID-19 epidemic cross-sectional defined demonstrated enrolled evaluated expected France help IgG and IgM Immune status Interpretation median age Migration observation occurred participant performed positive Questionnaires SARS-CoV-2 SARS-COV-2 infection Satisfaction serological Serological assay Switzerland verbal [DOI] 10.1371/journal.pone.0240779 PMC 바로가기 [Article Type] Research Article
Characteristics of recovered COVID-19 patients with recurrent positive RT-PCR findings in Wuhan, China: a retrospective studyResearch Article Published on 2020-10-132022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Antibody detection Clinical characteristics Controlled coronavirus coronavirus disease COVID-19 current Follow-up hospital Hospitalized hospitalized patient IgG outbreak Patient positive positive RT-PCR Rapid diagnostic test RDT recovered COVID-19 patient recovered patient recovered patients Recurrent Registered rehabilitation Result Retrospective study RT-PCR SARS-CoV-2 serological specimen throat swab throat swabs Transmission virus Wuhan Wuhan, China [DOI] 10.1186/s12879-020-05463-z PMC 바로가기 [Article Type] Research Article
A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds새로운 세포 내 ELISA 분석을 통해 SARS-CoV-2의 신속하고 자동화된 정량화를 통해 중화 항체 및 항바이러스 화합물 분석Immunology Published on 2020-10-092022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition antibodies Antigen antiviral agent Antiviral agents antiviral drug antiviral drugs antiviral interferon antiviral interferons Applying approach automated caused Cell culture cell lines Compound convalescent plasma convalescent sera coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 diagnostics dose doses Duration of infection Efficacy ELISA ELISAs equipment evaluate human sera Immunity immunity certificates infected cells interferon interferons NAb NAbs neutralization Neutralization assay neutralization test neutralization tests Neutralizing novel optimization other coronaviruses parameter plaque reduction neutralization PRNT quantification Quantitative raised Rapid reagent reagents reduced respiratory SARS-CoV-2 SARS-CoV-2 neutralization SARS-CoV-2 PRNT SARS-CoV-2-infected cell SARS-CoV-2-infected cells serological severe acute respiratory syndrome Coronavirus the SARS-CoV-2 time-consuming Vaccine vaccine candidate virus virus infection virus-neutralizing antibodies virus-neutralizing antibody virus-specific antibodies viruses [DOI] 10.3389/fimmu.2020.573526 PMC 바로가기 [Article Type] Immunology
COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions?Review Published on 2020-10-082022-10-30 Journal: Journal of Fungi [Category] COVID-19, [키워드] acute respiratory distress antibiotic use ARDS Candida Candidemia candidiasis candiduria clinical clinical factors Combination Complication COVID-19 COVID-19 patient COVID-19 patients develop diagnose diagnostic drug echinocandin fungal infections global pandemic high mortality rate ICU Immune cell immune dysregulation Immunity increasingly Infection invasive key factor mechanism molecular multidrug-resistant Mycobiome oral candidiasis Patient reported required risk serological severe COVID-19 syndrome therapeutic treat venous yeast [DOI] 10.3390/jof6040211 PMC 바로가기 [Article Type] Review
COVID-19: molecular and serological detection methodsMicrobiology Published on 2020-10-072022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome agency approach authorization caused Contact coronavirus COVID-19 COVID19 CRISPR-Cas12 develop diagnose Diagnostic method disadvantage droplets drug early stage ELISA Emergency food gold standard Health highlight ID NOW COVID-19 isothermal amplification knowledge lack LFA molecular mortality rates organization pandemic disease positive-sense RNA rRT-PCR SARS-CoV-2 serological Spread viral infection virus World Health Organization [DOI] 10.7717/peerj.10180 PMC 바로가기 [Article Type] Microbiology
Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)Immunology Published on 2020-10-022022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Activation acute exacerbation acute respiratory distress Analysis ARDS autoantibodies autoantibody Autoimmune Autoimmunity clinical Clinical course collagen Computed tomography connective tissue connective tissue disease coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients detection determine died disease ENA enrolled exacerbating Exacerbation feature fibroblast FIVE heterogeneous High-resolution histopathological finding Histopathology immunoblot immunofluorescence intensive care treatment Interstitial lung disease interstitial thickening investigated Laboratory testing mechanism objective Occurrence overlapping pathophysiology Patient Pneumonia positive predict Respiratory failure Result SARS-CoV-2 SARS-COV-2 infection serological severe complication severe COVID-19 significantly similarity syndrome the disease Therapeutic strategies tissue sample understanding was performed [DOI] 10.3389/fimmu.2020.587517 PMC 바로가기 [Article Type] Immunology
Molecular diagnosis of COVID-19 in different biologic matrix, their diagnostic validity and clinical relevance: A systematic reviewReview article Published on 2020-10-012022-10-05 Journal: Life sciences [Category] SARS, 진단, [키워드] ACE2angiotensin converting enzyme 2 addressed angiotensin converting enzyme 2 article assist biologic clinical decision conducted COVID 19 COVID-19 database diagnosis of COVID-19 diagnostic Effectiveness evaluate FETfield effect transistor field effect transistor Google Scholar ICTVInternational committee on taxonomy of viruses International committee on taxonomy of viruses lack LAMPloop-mediated isothermal amplification limit of detection localized surface plasmon resonance LoDlimit of detection Loop-mediated isothermal amplification LSPRLocalized surface plasmon resonance molecular observation outbreak overcome Patient point of care required Research researcher RT-PCR SARS-CoV-2 screened searched Sensitivity and specificity serological Serological testing Support systematic review the disease therapeutic strategy utility Vaccine Validity veterinary validation of point-of-care diagnostic instrument VIVALDIveterinary validation of point-of-care diagnostic instrument Web of Science [DOI] 10.1016/j.lfs.2020.118207 [Article Type] Review article
Multicenter evaluation of two chemiluminescence and three lateral flow immunoassays for the diagnosis of COVID-19 and assessment of antibody dynamic responses to SARS-CoV-2 in TaiwanResearch Article Published on 2020-10-012022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV 95% CI 95% confidence interval Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome antibody Antibody Response antibody tests autoantibodies Characteristics chemiluminescence chemiluminescence immunoassay chemiluminescence immunoassays CMV coronavirus coronavirus disease COVID-19 COVID-19 infection cross-reactivity demonstrated Diagnosis diagnosis of COVID-19 diagnostic evaluate FIVE IgG/IgM antibody Infection Interpretation lateral flow immunoassay Lateral flow immunoassays LFIAs multicenter non-COVID-19 patient Patient patient with COVID-19 patients with COVID-19 Pneumonia Rapid response Retrospective study risk Roche SARS-CoV-2 sensitivity sera Seroconversion seroconversion time serological serological test serum sample specificity suggested symptom onset Taiwan Test [DOI] 10.1080/22221751.2020.1825016 PMC 바로가기 [Article Type] Research Article