CD4 and CD8 Lymphocyte Counts as Surrogate Early Markers for Progression in SARS-CoV-2 Pneumonia: A Prospective StudyCD4 및 CD8 림프구는 SARS-CoV-2 폐렴의 진행을 위한 대리 조기 마커로 계산: 전향적 연구Article Published on 2020-11-092022-09-10 Journal: Viruses [Category] SARS, 바이오마커, [키워드] Admission appear Area association AUC best bilateral pneumonia CD3+CD4+ CD3+CD8+ CD4 CD4+ CD4+ T cells CD8 Complete count COVID-19 criteria Critical Curve decrease demographics disease dysregulation evaluate Evolution Factor Follow-up high correlation Hospital admission hospital discharge involved IQR Laboratory tests Linear regression model linear regression models lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes median medical history parameter pathophysiology Patient patients with SARS-CoV-2 Pneumonia Predictive Predictive value predictive values Prospective prospective cohort study receiver receiver operating characteristic recruited ROC ROC Curve ROC curves SARS-CoV-2 SARS-COV-2 infection severe disease severity subset suggested surrogate T cell T cells Treatment were recorded were used [DOI] 10.3390/v12111277 PMC 바로가기 [Article Type] Article
Ocular surface manifestations of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysisResearch Article Published on 2020-11-052022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome CINAHL conducted confirmed COVID-19 case coronavirus coronavirus disease COVID-19 COVID-19 patient cross-sectional study database determine diagnosed discharge feasible Features follicular Google heterogeneity manifestation Manifestations Meta-analysis Occurrence ocular ocular pain Ocular surface Pain Patient patients proportion Prospective reported Result RNA SARS-CoV-2 severe pneumonia specimen systematic review Viral RNA was performed was used Web of Science [DOI] 10.1371/journal.pone.0241661 PMC 바로가기 [Article Type] Research Article
Biomarkers of Hypercoagulability and Endothelial Cell Activation in Patients with Severe COVID-19 Admitted at the Intensive Care Unit. the Roadmap-COVID-19 Prospective Observational StudyConference abstract Published on 2020-11-042022-10-05 Journal: Blood [Category] 바이오마커, [키워드] Activation acute respiratory distress acute respiratory syndrome Algorithm Antithrombotic AP-HP ARDS Biomarker Blood coagulation calculated cause cellular change characterized clinically clotting factor Cluster Coagulation cohort study complications consecutive patient Control control group controls coronavirus coronavirus disease COVID-19 D-dimer decrease disease download effect of treatment endothelial Endothelial cell Endothelial dysfunction enrolled evaluate evaluated excessive inflammation expressing fibrinogen FVIII healthy individual Heparanase Hospitalized hypercoagulability ICU ICU admission ICU patient IL-6 IL-6 level increase indicate indicated inflammatory reaction Inhaled inhibitor intensive care unit intrinsic life-threatening LMWH management mandatory Microparticle moderate modify molecular weight monomer MRI Multisystem organ failure outcome Paris pathway Patient patients patients hospitalized patients with COVID-19 peak platelet activation Pneumonia Prospective Prospective Study Protein protein S ranged Ratio Respiratory failure Result SARS-CoV-2 SARS-COV-2 infection severe COVID-19 shown significant decrease significantly STABLE syndrome table TFPI the mean the patient thrombin Thromboprophylaxis university von Willebrand factor were assessed with COVID-19 [DOI] 10.1182/blood-2020-140275 [Article Type] Conference abstract
Prospective Study in 355 Patients With Suspected COVID-19 Infection: Value of Cough, Subjective Hyposmia, and HypogeusiaCOVID-19 감염이 의심되는 환자 355명을 대상으로 한 전향적 연구: 기침, 주관적인 저산소증 및 저체온증의 가치Article Published on 2020-11-012022-09-11 Journal: The Laryngoscope [Category] SARS, 치료기술, [키워드] Analysis analyzed association Care case-control study Chain Reaction characteristic conducted control groups coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 infection COVID-19 symptoms disorders evaluate Fever health worker health workers higher odd hospital Hypogeusia Hyposmia Hyposmia, hypogeusia, COVID-19, odds ratio, incidence, ROC. incidence incidence of COVID-19 Infection Laryngoscope Level negative RT-PCR Odds ratio olfactory function Patient patient groups patients polymerase chain polymerase chain reaction positive RT-PCR Positive test Prospective real-time polymerase chain reaction receiver operating characteristic ROC RT-PCR self-assessment Sensitivity and specificity significantly Subjective Suspected Symptom Symptoms value Visual Visual analog scales were used [DOI] 10.1002/lary.28999 PMC 바로가기 [Article Type] Article
[Variables associated with mortality in a selected sample of patients older than 80 years and with some degree of functional dependence hospitalized for COVID-19 in a Geriatrics Service][노인과 서비스에서 COVID-19로 입원한 80세 이상 및 어느 정도 기능적 의존성을 가진 환자의 선별된 샘플에서 사망률과 관련된 변수]Observational Study Published on 2020-11-012022-09-11 Journal: Revista española de geriatría y gerontología [Category] SARS, 임상, 치료기술, [키워드] age Analysis analyzed bivariate analysis cardiovascular cardiovascular disease Care carried characteristics of patient Chronic kidney disease CKD Cognitive impairment collected Comorbidity condition coronavirus disease Coronavirus disease 2019 COVID-19 Dependencia funcional Deterioration determine develop diagnostic Dyspnea Elderly patient elderly patients English Epidemic ERC Factor Factors Fever functional Functional impairment Functional status geriatric assessment Health healthcare high mortality rate higher risk Hospitalized hypertension identify In-hospital include Kidney disease laboratory-confirmed Laboratory-confirmed COVID-19 material media Mental moderate-severe Mortalidad Mortality mortality rate observational study Older older patient older patients outbreak outcome Pandemia Patient patients older Persona Personas mayores Prospective prospective observational study prospectivo radiological renal SARS-CoV-2 SARS-CoV-2 pandemic selected service Spanish Symptom therapeutic variable women [DOI] 10.1016/j.regg.2020.07.002 PMC 바로가기 [Article Type] Observational Study
Personnel Well-Being in the Helsinki University Hospital during the COVID-19 Pandemic—A Prospective Cohort StudyArticle Published on 2020-10-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] anxiety symptoms Asymptomatic baseline COVID-19 COVID-19 pandemic COVID-19 patient Depression District event Finland Finnish Follow-up healthcare personnel Helsinki highlight information Insomnia involved limit measure medical doctors pandemic Patient care Post-traumatic stress disorder Prospective Psychological distress psychological symptom reported Sociodemographic characteristics Support took place university Uusimaa while [DOI] 10.3390/ijerph17217905 PMC 바로가기 [Article Type] Article
COVID-19: What Iodine Maps From Perfusion CT can reveal—A Prospective Cohort StudyResearch Published on 2020-10-212022-11-01 Journal: Critical Care [Category] COVID-19, MERS, [키워드] 95% CI abnormality Admission admitted to ICU All participant anatomical angiotensin converting enzyme 2 Angiotensin II Anomaly carried change clinical outcomes Computed tomography angiography consolidation coronavirus COVID-19 COVID-19 patient COVID-19 patients D-dimer level death distribution Endpoint endpoints evidenced extension feature Ground-glass opacities ground-glass opacity healthy hospital discharge Hospitalization hospitals ICU IMV Invasive mechanical ventilation Iodine lung lung CT scan lung parenchyma Map material men Mild moderate morphologically Patient patients patients with COVID-19 pattern Perfusion Pneumonia predominant Probability Prospective prospective cohort study required Result SARS-COV-2 infection used to evaluate Vascular vasoconstriction Vasoplegia Ventilation-perfusion ratio was obtained [DOI] 10.1186/s13054-020-03333-3 PMC 바로가기 [Article Type] Research
Emerging Molecular Prospective of SARS-CoV-2: Feasible Nanotechnology Based Detection and InhibitionMicrobiology Published on 2020-10-202022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] affected Antiviral Apoptosis autophagy cascade change changes Community components COVID-19 death demonstrated detection diagnostics dissemination Endoplasmic reticulum Epidemiology Epigenetic event Genetic genetics and epigenetics global pandemic highlight host cell host’s immune response Inflammasome inhibition medications molecular mortality rate nanobased diagnosis nanobased therapeutics Nanotechnology outbreak Probability Prospective SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis Scientific community Stress target cells the SARS-CoV-2 therapeutic options unfolded protein response UPR viral infection viral replication viral-induced Worldometer [DOI] 10.3389/fmicb.2020.02098 PMC 바로가기 [Article Type] Microbiology
Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker복합 바이오마커로서 아연, 연령 및 셀레노단백질 P에 의한 COVID-19의 생존 확률 예측Clinical Trial Published on 2020-10-202022-08-13 Journal: Redox Biology [Category] MERS, SARS, 바이오마커, 임상, [키워드] age an area Analysis AUC Biomarker characteristic collected Concentration contribute convalescence coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients deficiency deficit different time point different time points EpiC EPIC cohort European healthy subject healthy subjects Hypothesis immune response immune system Inflammation information investigation majority Micronutrient non-survivor Non-survivors nutrition pandemic Patient personalised prediction Prevalence prognostic Prospective provide receiver operating characteristic reference range reference ranges ROC SARS-COV-2 infection SARS-CoV-2 infections Se transporter selenoprotein P Selenium SELENOP Selenoprotein P serum serum sample serum samples status Support survival survival odd survivor tested threshold Trace element trace elements was determined were used yielding Zinc [DOI] 10.1016/j.redox.2020.101764 PMC 바로가기 [Article Type] Clinical Trial
Analytical and Clinical Validation for RT-qPCR Detection of SARS-CoV-2 Without RNA ExtractionMedicine Published on 2020-10-152022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] amplification automated buffer clinical clinical decision clinical impact Concordance condition Contagion COVID-19 COVID-19 pandemic Cq value detection Diagnosis diagnostic direct RT-qPCR evaluated extraction include Laboratory limit limit of detection Nasopharyngeal swab pandemic (COVID-19) Prospective protocol RNA RNA extraction RT-qPCR Safe SARS-CoV-2 SARS-CoV-2 RNA selected Shock shortage of reagent validation was selected widespread [DOI] 10.3389/fmed.2020.567572 PMC 바로가기 [Article Type] Medicine