Age Related Differences in Monocyte Subsets and Cytokine Pattern during Acute COVID-19—A Prospective Observational Longitudinal Study급성 COVID-19 동안 단핵구 하위 집합 및 사이토카인 패턴의 연령 관련 차이 - 전향적 관찰 종단 연구Clinical Trial Published on 2021-11-302022-09-11 Journal: Cells [Category] MERS, SARS, 바이오마커, 임상, [키워드] accompanied Activation adverse outcome adverse outcomes age aging analyzed change circulating complex confounding factor confounding factors COVID-19 COVID-19 disease COVID-19 pandemic COVID-19 patients cytokine Cytokines difference Disease progression dysregulated immune response dysregulated immune responses Hospitalization IL-6 IL-8 immune response immune responses immunoparalysis individual infection with SARS-CoV-2 inflammaging Inflammatory cytokine Inflammatory cytokines innate immune response interleukin interleukin 6 longitudinal marker mechanism monocyte Monocyte activation Monocytes Necrosis Non-survivors older patient older patients outcome Pathogenesis patients pattern Phenotypes progression Prospective risk SARS-COV-2 infection subset survivor symptom onset Threats TNF Tumor tumor necrosis tumor necrosis factor Viral vulnerability [DOI] 10.3390/cells10123373 PMC 바로가기 [Article Type] Clinical Trial
Use of Monoclonal Antibodies Therapy for Treatment of Mild to Moderate COVID-19 in 4 Patients with Rheumatologic Disorders4명의 류마티스 질환 환자에서 경증에서 중등도의 COVID-19 치료를 위한 단일클론항체 요법의 사용Case Reports Published on 2021-11-252022-09-12 Journal: Medical science monitor : international medical jo [Category] MERS, SARS, 진단, [키워드] adverse outcomes case sery conducted Coronavirus disease 2019 Corticosteroid COVID-19 disease Diseases effective therapy Efficacy EUA FDA form hospital illness immunosuppressive increase information MAT a Mild moderate monoclonal antibody Patient protocol receiving retrospective rheumatological rheumatological disorder risk Safe therapy treated treating COVID-19 [DOI] 10.12659/MSM.934267 PMC 바로가기 [Article Type] Case Reports
The impact of COVID-19 on people who inject drugs in New York City: increased risk and decreased access to servicesCovid-19가 뉴욕시에 약물을 주입하는 사람들에게 미치는 영향 : 위험 증가 및 서비스 접근 감소Randomized Controlled Trial Published on 2021-11-242022-08-31 Journal: Harm Reduction Journal [Category] MERS, SARS, 임상, 치료기술, 치료제, [키워드] adverse outcome adverse outcomes affected alcohol alcohol consumption Analysis Big events Buprenorphine Care Community conducted COVID-19 criteria cross-sectional analysis detectable drug eligibility criteria event events greater HCV help IMPROVE increased risk injection maintain mental health mental health issues negatively affected New York New York City pandemic participant Participants People who inject drugs provide randomized trial recruited reductions in reported response Result reuse risk RNA significantly higher study group Substance use Treatment Trial registration usual care while [DOI] 10.1186/s12954-021-00568-3 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Predictive Value of Myoglobin for COVID-19-Related Adverse Outcomes: A Systematic Review and Meta-AnalysisCardiovascular Medicine Published on 2021-11-182022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] 95% CIs 95% confidence interval Adverse adverse outcomes Anomaly article Biomarker cardiac injury cardiac troponin Cardiac troponin I coronavirus disease correlation COVID-19 COVID-19 prognosis database demonstrated elevated Elevation enrolled estimate examined General population higher odd marker meta-analyses Meta-analysis Mortality Myoglobin Odds ratio outcomes Patient patients with COVID-19 Predictive value Prevalence PROSPERO Registration review risk searched severe COVID-19 severe disease severe illness significantly higher value Web of Science with COVID-19 [DOI] 10.3389/fcvm.2021.757799 PMC 바로가기 [Article Type] Cardiovascular Medicine
Association of Substance Use With Behavioral Adherence to Centers for Disease Control and Prevention Guidelines for COVID-19 Mitigation: Cross-sectional Web-Based SurveyOriginal Paper Published on 2021-11-092022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, SARS, [키워드] 95% CI accounted Addiction adherence Administered adverse outcomes age alcohol alcohol drinking Alcohol use Amazon’s Mechanical Turk Analysis black CDC center Connecticut Control covariate COVID-19 COVID-19 infection COVID-19 mitigation COVID-19 testing cross-sectional Daily determine drug elevated eligible evaluate finding Gender greater guideline Hispanic Hypothesis identity individual individuals likelihood Massachusetts men mental health New New York Nicotine Novel coronavirus objective Older Opioid use outcome pandemic platform positive COVID-19 prevention Primary outcome recruited reduce reported Result Rhode Island risk risk factor Risk factors SARS-CoV-2 secondary smoking Sociodemographic Sociodemographic characteristics spread of COVID-19 statistically stimulant use substance substance abuse Substance use Support survey tested vaccination variables was related white women [DOI] 10.2196/29319 PMC 바로가기 [Article Type] Original Paper
COVID-19 and renal infarct: To be or not to be on anticoagulationCase Report Published on 2021-11-092022-11-01 Journal: Clinical Nephrology. Case Studies [Category] COVID-19, [키워드] adverse outcomes anticoagulation antiplatelet approach arterial thrombi Aspirin Castleman disease clinician Complication COVID-19 COVID-19 diagnosis Diagnosis disease high risk highlight Infection inpatient admission low-dose male management medical resource Mild morbidity Oral anticoagulants Patient presenting Pulmonary emboli renal Renal Infarction risk spleen infarct therapy thrombosis thrombotic complication unique Vascular vascular thrombosis venous with COVID-19 [DOI] 10.5414/CNCS110602 PMC 바로가기 [Article Type] Case Report
D-dimer, disease severity, and deaths (3D-study) in patients with COVID-19: a systematic review and meta-analysis of 100 studiesCOVID-19 환자의 D-dimer, 질병 중증도 및 사망(3D 연구): 100개 연구에 대한 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-11-082022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, [키워드] adjusted adjusted hazard ratio adjusted odds ratio adverse outcome adverse outcomes association Biochemistry Biomarkers clinician Coagulation COVID-19 COVID-19 patient COVID-19 patients D-dimer D-dimer level death dimer Disease progression disease severity Diseases hazard ratio hypercoagulability information initial marker Meta-analysis Mortality Odds ratio outcome outcomes Patient patients with COVID-19 prognostic PROSPERO Registered risk Risk factors risk for disease systematic review [DOI] 10.1038/s41598-021-01462-5 PMC 바로가기 [Article Type] Meta-Analysis
SARS-CoV-2 vaccine uptake in a multi-ethnic UK healthcare workforce: A cross-sectional studyResearch Article Published on 2021-11-052022-10-29 Journal: PLoS Medicine [Category] COVID-19, MERS, SARS, [키워드] 95% CI absence acute respiratory syndrome adjusted odds ratio adverse outcomes age association black Care Characteristics Christopher Cohort collected data conducted confounders coronavirus COVID-19 COVID-19 infection COVID-19 test COVID-19 vaccination cross-sectional data extraction dataset Demographic factors Deprivation determine Determining effective evaluate Evidence examined Factor Factors female females group groups HCW HCWs Health healthcare healthcare worker Healthcare workers high risk hospital identify implication IMPROVE include increased risk Intervention lack less limitation Logistic regression National NHS offer pandemic Patient PCR predictor Pregnancy pregnant Prevent proportion PROTECT Research researcher risk of infection SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Sex significantly significantly lower South South Asian stratified Surveillance targeted intervention tested the patient These data Topic Trust university vaccination vaccination against COVID-19 Vaccine white [DOI] 10.1371/journal.pmed.1003823 PMC 바로가기 [Article Type] Research Article
Altered Mental Status: An Important but Overlooked Presenting Symptom of COVID-19 in Older AdultsObservational Study Published on 2021-11-012022-10-05 Journal: The American journal of geriatric psychiatry : official journal of the [Category] SARS, 임상, [키워드] 95% CI Acute cardiac injury Acute kidney injury acute respiratory distress Admitted Patient adverse outcomes age AKI Algorithm Altered Altered mental status AMS Clinical course COVID-19 determine diagnostic Geriatrics global pandemic greater healthcare help increased risk intubation Mortality multivariate regression analysis Older pandemic Patient patients positive COVID-19 presenting prognostic indicator reduce retrospective single center Symptom syndrome was used with COVID-19 [DOI] 10.1016/j.jagp.2021.06.004 PMC 바로가기 [Article Type] Observational Study
Heart-rate-variability (HRV), predicts outcomes in COVID-19심박수 변동성(HRV), COVID-19의 결과 예측Research Article Published on 2021-10-282022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] Admission adverse outcome adverse outcomes Asymptomatic disease bpm bradycardia Cardiac arrhythmia cardiac arrhythmias clinical manifestations consecutive patient COVID-19 COVID-19 infection death determine diagnosed ECG examined greater heart rate Hospitalization Hospitalized HRV ICU immune response independent independent of Inflammation intensive care intensive care unit interval marker median value Mild Mortality Older outcome pacemaker Patient patients hospitalized predict predicted Premature Premature contractions Previous studies previous study Prognostic factors Prognostic value protective role recorded Result retrospective cohort study risk Standard deviation survival Tachycardia vagus nerve variety ventricular with COVID-19 younger patients [DOI] 10.1371/journal.pone.0258841 PMC 바로가기 [Article Type] Research Article