Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortalityObservational Study Published on 2022-06-012022-10-05 Journal: Intensive care medicine [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI acute respiratory distress adjusted Adjusted analysis affected association Blood CMV coronavirus disease COVID-19 Cox proportional hazard Critically ill Critically ill patient cytomegalovirus Cytomegalovirus reactivation Effect evaluated Hospital mortality ICU ICU admission ICU patient incidence increased risk intensive care Invasive mechanical ventilation large cohort Mechanical mechanical ventilation Mortality Occurrence outcome Patient Physiology Platelet Quantitative regression models risk factor SARS-COV-2 infection score screened secondary bacterial infection Sepsis severity syndrome worsening [DOI] 10.1007/s00134-022-06716-y PMC 바로가기 [Article Type] Observational Study
Urinary tubular biomarkers as predictors of death in critically ill patients with COVID-19COVID-19에 걸린 중환자의 사망 예측인자로서의 요세관 바이오마커Article Published on 2022-06-012022-09-11 Journal: Biomarkers in Medicine [Category] MERS, 바이오마커, [키워드] association Biomarker Biomarkers COVID-19 COVID-19 infection COVID-19 patients Cox regression analysis Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients cut-off value death evaluate had no ICU admission kidney kidney biomarkers. MCP-1 multivariate multivariate Cox regression analysis nephrin NGAL Patient predict predictor Prospective Study Proteinuria quantified regression analysis survival tubular urinary with COVID-19 worse prognosis [DOI] 10.2217/bmm-2021-0631 PMC 바로가기 [Article Type] Article
Aberrant Fibrin Clot Structure Visualized Ex Vivo in Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 InfectionObservational Study Published on 2022-06-012022-10-05 Journal: Critical Care Medicine [Category] 임상, [키워드] acute respiratory syndrome age anticoagulation assessment Biomarkers body mass index buffer clot Coagulation Cohort Comorbidities contribute coronavirus coronavirus 2 COVID-19 COVID-19 patient Critically ill patient cross-sectional determine died failure fibrin clot fluorescent functional Gender ICU ICU admission ICU patient Ill implication Infection interquartile range Laboratory measurement median microthrombi Mortality outcome Patient patients with COVID-19 patients without COVID-19 plasma positively correlated reported required respiratory Sepsis SOFA SOFA score Structure was collected was used widespread with COVID-19 [DOI] 10.1097/CCM.0000000000005465 PMC 바로가기 [Article Type] Observational Study
COVID-19 infection: an overview on cytokine storm and related interventionsCOVID-19 감염: 사이토카인 폭풍 및 관련 중재에 대한 개요Review Published on 2022-05-262022-09-12 Journal: Virology Journal [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory distress acute respiratory syndrome Affect ARDS ARDS patient cause caused conditions Coronavirus disease 2019 Coronavirus-2 COVID-19 Critically ill patient CRS Cytokine storm death defined Efficacy elevated Health IL-1 IL-17 IL1 IL6 impairment IMPROVE Infection Inflammatory response interleukin-6 Interleukins Intervention lung damage Patient patients with COVID-19 Pneumonia pro-inflammatory pro-inflammatory cytokines respiratory epithelium respiratory tract SARS-CoV-2 specific inhibitor specific treatment survival rate syndrome systemically TNF-α triggered tumor necrosis factor-alpha virus [DOI] 10.1186/s12985-022-01814-1 PMC 바로가기 [Article Type] Review
Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndromeObservational Study Published on 2022-05-232022-10-05 Journal: Critical Care [Category] 임상, [키워드] acute respiratory distress adjusted Analysis ARDS Bilirubin Chemical Chemical and drug-induced liver injury Cholangiopathy Cholangitis cholestasis competing confidence interval COVID-19 patient COVID-19 patients COVID-19-associated ARDS Critically ill Critically ill patient cumulative doses High-dose Hypnotics and sedatives. ICU incidence infused Ketamine liver Liver injury mechanically ventilated mechanically ventilated patient mixed-effects model multivariable Patient positively correlated post-hoc analysis propofol prospective observational cohort receiving regimen rising risk Sedation shown syndrome total bilirubin [DOI] 10.1186/s13054-022-04019-8 PMC 바로가기 [Article Type] Observational Study
TTCOV19: timing of tracheotomy in SARS-CoV-2-infected patients: a multicentre, single-blinded, randomized, controlled trialRandomized Controlled Trial Published on 2022-05-182022-10-05 Journal: Critical Care [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI acute respiratory distress adverse events age assigned Complication correlation COVID-19 COVID-19 patient Critically ill patient death rate develop evaluate Götaland group groups intensive care intention-to-treat analysis intubation IQR males Mechanical mechanical respiratory mechanical ventilation median multicentre no significant difference observational study Patient per-protocol analysis protocol Randomized controlled trial randomized, controlled trial Randomly reduced Region Registered Respiratory Support SARS-CoV-2-infected patient selected significantly Spearman suggested Support survival syndrome the timing time Time factors tracheotomy treatment regimen with COVID-19 [DOI] 10.1186/s13054-022-04005-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Fibronectin as a Marker of Disease Severity in Critically Ill COVID-19 Patients중환자 COVID-19 환자의 질병 중증도 지표로서의 피브로넥틴Article Published on 2022-05-062022-09-11 Journal: Cells [Category] Coronavirus, COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] Alter APACHE II Bacterial Bacterial sepsis Biomarker Biomarkers can be used cellular clinical setting clinical settings correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 sample COVID-19 samples Critically ill Critically ill patient critically ill patients disease severity ELISA etiology expression of gene Extracellular matrix Fibronectin form help Ill immune response immunoblotting Infection Intensive intensive care intensive care unit knowledge MONITOR Mortality mortality prediction no significant difference no significant differences Non-survivors outcomes Patient plasma predict Proteins proteolytic Research SARS-CoV-2 virus Sepsis significantly higher SOFA scores treated Treatment Treatment outcome Viral was related were measured [DOI] 10.3390/cells11091566 PMC 바로가기 [Article Type] Article
Low phase angle is associated with 60-day mortality in critically ill patients with COVID-19낮은 위상각은 COVID-19 중환자의 60일 사망률과 관련이 있습니다.Article Published on 2022-05-012022-09-11 Journal: JPEN. Journal of parenteral and enteral nutrition [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus Admission Analysis association bioelectrical impedance Bioelectrical Impedance Analysis biological marker body composition body water clinical outcomes coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill Critically ill patient critically ill patients Cutoff death Extracellular female hazard ratio Hospital stay increased risk intensive care intensive care unit admission Kaplan-Meier curves Linear regression model male Malnutrition mechanical ventilation mechanically ventilated patient mechanically ventilated patients Mortality mortality risk nutrition risk nutrition status Odds ratio on mechanical ventilation parameter Pathologies Patient Phase angle predictor prospective cohort risk Risk assessment SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly increased survival analysis variable was performed water were used with COVID-19 [DOI] 10.1002/jpen.2236 PMC 바로가기 [Article Type] Article
The role of Monocyte Distribution Width (MDW) in the prognosis and monitoring of COVID-19 patientsCOVID-19 환자의 예후 및 모니터링에서 단핵구 분포 폭(MDW)의 역할Article Published on 2022-05-012022-09-11 Journal: Clinical biochemistry [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, [키워드] age AUC Beckman Coulter blood count blood sample calculated complete blood count correlated COVID-19 COVID-19 patient COVID-19 patients Critically ill Critically ill patient critically ill patients cut-off diagnostic distribution Efficacy enrolled form hospitalisation ICU less monocyte Monocyte Distribution Width (MDW) non-survivor not significant outcome parameter Patient patients procalcitonin Prognosis prognostic reported SARS-CoV-2-positive patient Sensitivity and specificity severe forms of COVID-19 shown significantly Standard deviation Support Surveillance Survivors the mean unfavourable prognosis was used width [DOI] 10.1016/j.clinbiochem.2022.02.007 PMC 바로가기 [Article Type] Article
Oxygen therapy limiting peripheral oxygen saturation to 89-93% is associated with a better survival prognosis for critically ill COVID-19 patients at high altitudesObservational Study Published on 2022-05-012022-10-04 Journal: Respiratory physiology & neurobiology [Category] 임상, [키워드] Alto association automatically Blood central respiration connection COVID-19 COVID-19 patient Critically ill Critically ill patient cross-sectional death evaluated event expected fraction Frequency help high-altitude hyperoxemia Hypoxemia hypoxemic ICU IMPROVE intensive care intensive care unit intubated patient intubated patients intubation Invasive mechanical ventilation liberal liberal oxygen therapy life-threatening limit maintain Mortality multicenter normoxemia. normoxia overcome oxygen Oxygen therapy Oxygenation PaO Patient peripheral oxygen saturation Prognosis receive required Respiratory failure rises SOFA score suggested Support survival therapy undergo was performed [DOI] 10.1016/j.resp.2022.103868 PMC 바로가기 [Article Type] Observational Study