Antiplatelet therapy and outcome in COVID-19: the Health Outcome Predictive Evaluation RegistryObservational Study Published on 2022-01-012022-10-04 Journal: Heart (British Cardiac Society) [Category] 임상, [키워드] 95% CI anticoagulation antiplatelet Aspirin bleeding clinical consecutive patient COVID-19 diabete drugs Efficacy embolic enrolled evaluate event hospitalisation hospitalised patient In-hospital in-hospital complication in-hospital mortality increased risk International invasive ventilation lower mortality lower mortality risk male mechanical ventilation microthrombi multicentre multivariable analysis no difference Older organs outcome Patient Pharmacology Prevalence registry risk Standard survival therapy therapy for COVID-19 treated were recorded with COVID-19 [DOI] 10.1136/heartjnl-2021-319552 PMC 바로가기 [Article Type] Observational Study
Editor’s Choice – Update of the European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Acute Limb Ischaemia in Light of the COVID-19 Pandemic, Based on a Scoping Review of the LiteratureReview article Published on 2022-01-012022-10-05 Journal: European journal of vascular and endovascular surgery : the official [Category] SARS, 임상, [키워드] acute limb ischaemia affected affecting anaesthesia arterial thromboembolic event Case report Case series changed choice clinical concerning COVID-19 COVID-19 infection CTA D-dimer defined dosage Epidemiology European evaluate greater guideline heparin hospitalised COVID-19 patient hospitalised patient incidence include LIGHT limb literature Local measure Modification MOST objective Occurrence outcome pandemic Patient patients patients with COVID-19 Peripheral arterial disease Practice predict Prophylactic proportion Protective question randomised controlled trial recommendation remained remains uncertain reported Result retrieved review severe COVID-19 Society surgery systematic literature search Treatment unique upper limb was performed [DOI] 10.1016/j.ejvs.2021.08.028 [Article Type] Review article
Association of the patterns of use of medications with mortality of COVID-19 infection: a hospital-based observational studyObservational Study Published on 2021-12-312022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] 95% CI ACE inhibitor ACE2 ACE2 expression ACE2 receptor Affair Affect analysed angiotensin receptor blocker ARB ARBs association benefit Beta blockers Cell condition COVID-19 COVID-19 diagnosis Cox proportional hazard death diagnosis of COVID-19 dysregulation Epidemiology examined hospitalised patient identify increased risk indicated Infection Initiating Injury Logistic regression magnitude medical record medication medications morbidity Mortality Patient patients with COVID-19 PROTECT public health randomised clinical trial Randomised trial recent reduced risk Remdesivir Result reverse transcription PCR SARS-CoV-2 statistically significant Support survival therapeutic potential Treatment veteran virus were used with COVID-19 [DOI] 10.1136/bmjopen-2021-050051 PMC 바로가기 [Article Type] Observational Study
Safety and Efficacy of Intermediate- and Therapeutic-Dose Anticoagulation for Hospitalised Patients with COVID-19: A Systematic Review and Meta-AnalysisReview Published on 2021-12-232022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI affected all-cause mortality anticoagulant therapy anticoagulation benefit bleeding certainty clinical status Coronavirus disease 2019 COVID-19 COVID-19 patient death decrease disease severity Efficacy Efficacy and safety Evidence hospitalised patient independent intermediate major bleeding meta-analysed moderate Patient patients patients with moderate randomised controlled trial RCTs regimen review risk Safety searched severe COVID-19 patients severe disease standard thromboprophylaxis thrombosis thrombotic thrombotic risk with COVID-19 [DOI] 10.3390/jcm11010057 PMC 바로가기 [Article Type] Review
Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort studyObservational Study Published on 2021-12-222022-10-04 Journal: BMJ Open [Category] Fulltext, SARS, 임상, [키워드] 95% CI acute respiratory distress adverse event adverse outcome arrhythmia Cohort cohort study Comorbidity COVID-19 COVID-19 patient database death diabetes diagnosed diagnosed with COVID-19 disease dyslipidaemia Epidemiology Europe female had more healthcare hospitalisation hospitalised hospitalised patient hypertension increased mortality individual Inpatient National obesity objective outcome outcomes outpatients participant partnership Patient patients with COVID-19 prevalent reported Result retrospective cohort study South Korea stratified study period syndrome USA with COVID-19 [DOI] 10.1136/bmjopen-2021-057632 PMC 바로가기 [Article Type] Observational Study
Limitation of life-sustaining treatment and patient involvement in decision-making: a retrospective study of a Danish COVID-19 patient cohortObservational Study Published on 2021-12-202022-10-04 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] SARS, 임상, [키워드] Admission age body mass index Characteristics Cohort Comorbidities conducted coronavirus COVID-19 COVID-19 patient Diagnosis end-of-life frailty Gender Healthcare system hospital Hospital admission Hospital admissions hospitalisation hospitalised patient hospitals ICU admission information Life-sustaining treatment limitation list Mental Mortality pandemic Patient Patient involvement patients Physicians proportion Registered Result retrospective Retrospective study risk Shared decision-making supplementary material the patient Treatment with COVID-19 [DOI] 10.1186/s13049-021-00984-1 PMC 바로가기 [Article Type] Observational Study
Evaluation of new or repurposed treatments for COVID-19: protocol for the phase Ib/IIa DEFINE trial platformCOVID-19에 대한 신규 또는 용도 변경 치료제 평가: Ib/IIa상 DEFINE 시험 플랫폼 프로토콜Article Published on 2021-12-152022-09-11 Journal: BMJ Open [Category] 임상, [키워드] acceptance adaptive administration Analysis Appropriate approval Arm ARMS assisted ventilation caused changes in clinical trial Coagulation Cohort Community Complete computer COVID-19 COVID-19 therapy dependent on development during treatment effective Efficacy Ethics ethics committee EudraCT Evidence evidence of Experimental medicine exploratory Follow-up hospital Hospital stay hospitalised patient Infection Infectious diseases information initial mechanism mechanism of action Medicine MHRA National Health Service NEWS2 NHS Novel coronavirus Open-label Ordinal Scale oxygen Oxygen requirements participant Pathways Patient patient cohorts patient safety patients with COVID-19 peer-reviewed pharmacokinetic Pneumonia Pneumonitis positive present product protocol randomisation randomised Randomised Evaluation REC recovery recruited recruitment registration number research and development Research Ethics Research Ethics Committee respiratory medicine (see thoracic medicine) Safe SARS-CoV-2 score secondary Standard of care statistical analysis submitted Support Therapeutics therapy Thoracic Treatment treatment arm treatment period Trial trial platform variable Viral load viral-induced WHO ordinal scale [DOI] 10.1136/bmjopen-2021-054442 PMC 바로가기 [Article Type] Article
The impact of therapeutics on mortality in hospitalised patients with COVID-19: systematic review and meta-analyses informing the European Respiratory Society living guideline코로나19 입원환자 사망률에 대한 치료제의 영향: 유럽호흡기학회 생활지침을 알려주는 체계적인 검토 및 메타분석Review Published on 2021-12-152022-09-11 Journal: European respiratory review : an official journal [Category] SARS, 치료제, [키워드] anti-IL-6 receptor Anti-inflammatory Anti-viral Azithromycin Colchicine comparator conducted coronavirus disease Coronavirus disease 2019 Corticosteroids COVID-19 Dexamethasone Effect estimate European Evidence guideline high mortality rate hospitalised patient Hospitalised patients Hydroxychloroquine identify inclusion criteria interferon International Intervention Lopinavir Lopinavir/ritonavir Meta-analysis monoclonal antibodies monoclonal antibody monoclonal antibody therapy Mortality other treatments outcome Patient question Random-effects meta-analysis randomised controlled trial Randomised controlled trials recommendation Remdesivir respiratory Ritonavir Society Support systematic review systematic reviews therapy These data Treatment use of corticosteroids was used with COVID-19 [DOI] 10.1183/16000617.0171-2021 PMC 바로가기 [Article Type] Review
Rehabilitation needs following COVID-19: Five-month post-discharge clinical follow-up of individuals with concerning self-reported symptomsResearch article Published on 2021-12-052022-10-05 Journal: EClinicalMedicine [Category] 임상, [키워드] affective Analysis auditory breathlessness clinical examination clinically cognitive Cognitive function Cognitive impairment Cohort cohort study complexity concerning Consequences COVID-19 detrimental fatigue finding FIVE Follow-up form functional healthcare hospital hospitalised patient hospitalized COVID-19 patient individual Intervention Linköping Long-term follow-up nonspecific Östergötland PACS Pain Patient performed post-COVID-19 primary care problem provided Region regions rehabilitation Rehabilitation need reported required Residual symptoms SARS-CoV-2 self-reported symptom survivor Swedish Symptom Symptoms translated weakness were assessed [DOI] 10.1016/j.eclinm.2021.101219 [Article Type] Research article
Soluble Urokinase Plasminogen Activator Receptor (suPAR) Independently Predicts Severity and Length of Hospitalisation in Patients With COVID-19Medicine Published on 2021-12-022022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] activator addition analysed Biomarker blood cell body mass index C-reactive protein (CRP Care Clinical outcome Complication Control correlated COVID-19 COVID-19 disease severity COVID-19 severity creatinine CRP death disease severity efficient enzyme-linked immunosorbent glomerular filtration rate healthcare healthy control Hospital stay hospitalisation hospitalised hospitalised patient ill patient independent individual Infection Kidney injury lactate dehydrogenase LDH Length Length of hospital stay Level males median median age median symptom neutrophil count Neutrophil-to-lymphocyte ratio other variables oxygen Patient patients with COVID-19 patients with SARS-CoV-2 plasma plasminogen predict predictor prognostic prognostic variable recorded reduce renal Respiratory failure risk serum shown significantly higher suPAR urokinase were measured with COVID-19 [DOI] 10.3389/fmed.2021.791716 PMC 바로가기 [Article Type] Medicine