Treatment for COVID-19—a cohort study from Northern ItalyCovid-19에 대한 치료-이탈리아 북부의 코호트 연구Observational Study Published on 2021-10-252022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, 치료법, 치료제, [키워드] Antiviral Azithromycin clinical evaluation cohort study Combination Corticosteroid COVID-19 patient COVID-19 therapeutics Epidemiology heparin High dose Italy low molecular weight low molecular weight heparin lower mortality multicentre multivariable retrospective cohort study Support survival Tocilizumab Treatment viral infection [DOI] 10.1038/s41598-021-00243-4 PMC 바로가기 [Article Type] Observational Study
Correlation of Country Characteristics and Government Response Measures With COVID-19 Mortality During the First Phase of the Global COVID-19 Pandemic: A Worldwide Ecological StudyInfectious Disease Published on 2021-10-112022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Bank conducted coronavirus disease correlated correlation correlations country COVID-19 COVID-19 case COVID-19 mortality database decreased mortality Gender geographic location Government Health healthcare highest initial Johns Hopkins University lockdown lower mortality material measure Mortality mortality rates multivariable negative correlation Older pandemic peak Pearson correlation coefficient phase positive correlation predictor produced Progress proportion public health Regression model reported Repository response Result Social Progress Index socioeconomic determinants of healthcare Socioeconomic factor specific treatment Vaccine variable were excluded worldwide pandemic [DOI] 10.7759/cureus.18689 PMC 바로가기 [Article Type] Infectious Disease
Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity인플루엔자 및 SARS-CoV-2 동시 감염의 치사율 증가는 인플루엔자 면역에 의해 예방되지만 SARS-CoV-2 면역은 예방되지 않습니다.Article Published on 2021-10-052022-09-12 Journal: Nature Communications [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antibodies Coinfection Comorbidity Complete coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic elevated ENhance IAV Immunity increase Increased Infection Influenza influenza A influenza A virus influenza vaccination influenza viral Influenza virus K18-hACE2 mice lower mortality mice morbidity Mortality mouse model organs outcome pandemic Prevent prevented Probability PROTECT reducing risk SARS-CoV-2 SARS-CoV-2 immunity SARS-COV-2 infection Seasonal influenza severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease Spread Support susceptibility the disease These data vaccination Viral host response viral loads virus [DOI] 10.1038/s41467-021-26113-1 PMC 바로가기 [Article Type] Article
Association of Serum Ferritin Levels and Methylprednisolone Treatment With Outcomes in Nonintubated Patients With Severe COVID-19 Pneumonia삽관하지 않은 중증 코로나19 폐렴 환자에서 혈청 페리틴 수치와 메틸프레드니솔론 치료의 결과와의 연관성Research Published on 2021-10-042022-09-25 Journal: JAMA Network Open [Category] MERS, SARS, 바이오마커, 진단, [키워드] 95% CI acute phase Administered Admission age Analysis analyzed Asian association baseline benefit Biomarker Black patient Clinical outcome cohort study Composite Corticosteroid COVID-19 daily dose death Effectiveness end point exposure ferritin ferritin level finding fraction functions high-flow oxygen therapy Importance Inflammation Laboratory Level lower mortality marker measure mechanical ventilation median Methylprednisolone Mortality New York objective outcome oxidative stress oxygen participant Patient Point Primary outcome Probability Protein receiving reduced Relevance reported Result retrospective cohort study secondary outcome Serum ferritin serum ferritin level setting severe COVID-19 Severe COVID-19 pneumonia systemic Treatment Treatment outcome treatment with methylprednisolone variables White patient [DOI] 10.1001/jamanetworkopen.2021.27172 PMC 바로가기 [Article Type] Research
Patients with schizophrenia have decreased COVID-19 prevalence among hospitalised patients with psychiatric and neurological diseases: A retrospective analysis in Mexican population정신 분열증 환자는 정신과 및 신경계 질환으로 입원한 환자들 사이에서 COVID-19 유병률을 감소시켰습니다: 멕시코 인구에 대한 후향적 분석Article Published on 2021-10-012022-09-11 Journal: International journal of clinical practice [Category] SARS, 치료기술, [키워드] 95% CI age analysed average Comorbidities coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic diagnoses Diagnosis disorder Effect First wave Gender General population hospital hospitalised hospitalised patient Hospitalised patients incidence Increased increased risk intellectual disability lower mortality medical diagnosis Mortality mortality rate National neurologic neurologic disorder neurologic disorders neurological Neurological disorder Neurological disorders Odds ratios Patient patients with comorbidities patients with comorbidity patients with COVID-19 predisposition Prevalence prevalence of COVID-19 Psychiatric psychiatric disorder Psychiatric disorders Psychiatric Hospital reported Retrospective analysis Schizophrenia Variation [DOI] 10.1111/ijcp.14528 PMC 바로가기 [Article Type] Article
The protective role of statins in COVID-19 patients: a retrospective observational studyResearch Published on 2021-09-252022-10-29 Journal: Translational Medicine Communications [Category] COVID-19, [키워드] C-reactive protein Comorbidities Comorbidity conducted confounders confounding factor Coronary artery disease cough COVID-19 COVID-19 patients D-dimer determine diabete diagnosed with COVID-19 Dyspnea Effect evaluate fatigue FIVE Hemodialysis hospital Hospitalization Hospitalized hypertension incidence India Inference laboratory result lower mortality males mechanical ventilation observation outcome Prevalence protective role Result retrospective retrospective cohort study statistical WBC [DOI] 10.1186/s41231-021-00102-4 PMC 바로가기 [Article Type] Research
Early versus late awake prone positioning in non-intubated patients with COVID-19COVID-19를 가진 intubated 환자에서 조기 대 늦게 깨어있는 낙인 위치Randomized Controlled Trial Published on 2021-09-172022-08-13 Journal: Critical Care [Category] 임상, [키워드] 28-day mortality Acute hypoxemic respiratory failure Adult patient Adult patients advanced age age app Awake prone positioning ClinicalTrials.gov NCT04325906 collected coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients defined HFNC High-flow nasal cannula Hydrocortisone hypoxemic Hypoxemic respiratory failure IMPROVE increased mortality initiated intubation intubation rate lower mortality male management median time nasal nasal cannula NCT04325906 no difference Non-intubated non-intubated patient outcome Patient per day post-hoc analysis Primary outcomes prone positioning Randomized controlled trial Respiratory failure Result secondary to survival Trial registration with COVID-19 [DOI] 10.1186/s13054-021-03761-9 PMC 바로가기 [Article Type] Randomized Controlled Trial
Ruxolitinib in severe COVID-19: Results of a multicenter, prospective, single arm, open-label clinical study to investigate the efficacy and safety of ruxolitinib in patients with COVID-19 and severe acute respiratory syndromeClinical Trial Published on 2021-09-072022-10-05 Journal: Revista de la Facultad de Ciencias Médicas (Córd [Category] 임상, [키워드] according to protocol acute respiratory syndrome added Admission Adult anti-inflammatory effect caused circulating cytokines clinical study coronavirus Coronavirus infections COVID-19 COVID-19 patients COVID-19 pneumonia patient Critical determine distress Effect Efficacy and safety elevated English Host ill patient immune response intensive care Janus kinase Janus kinase inhibitors lower mortality mechanical ventilation multicenter Open-label organ injury Patient patients patients with COVID-19 Phase 2 study primary endpoint prospectivo receiving reduction reported Respiratory distress syndrome Result ruxolitinib ruxolitinib dose side Spanish Standard of care study drug Toxicity Treatment [DOI] 10.31053/1853.0605.v78.n3.32800 PMC 바로가기 [Article Type] Clinical Trial
Tocilizumab and Systemic Corticosteroids in the Management of Patients with COVID-19: A Systematic Review and Meta-AnalysisCOVID-19 환자 관리에서 토실리주맙과 전신 코르티코스테로이드: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-09-012022-09-12 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, [키워드] 95% confidence interval adjusted association Combination coronavirus COVID-19 COVID-19 patients data extraction disease effective Efficacy estimate Health lower mortality mortality rate New coronavirus not differ outcome performed randomized trial Record review risk risk of bia SCT searched severe COVID-19 Standard of care study outcomes subject systemic systemic corticosteroid systemic corticosteroid therapy TCZ therapy Tocilizumab Treatment were used [DOI] 10.1016/j.ijid.2021.07.021 PMC 바로가기 [Article Type] Meta-Analysis
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA networkResearch Article Published on 2021-08-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Admission age Comorbidity Corticosteroid COVID-19 pneumonia patient Critically ill patient death French ICU Impact increased risk Inflammation lower mortality male mechanical ventilation median median age Mortality multicenter cohort study objective Occurrence Patient patient survival patients patients with COVID-19 Pneumonia Probability required Result risk Severe COVID-19 pneumonia significantly study population subgroup survival Treatment two groups Weighting [DOI] 10.1371/journal.pone.0255644 PMC 바로가기 [Article Type] Research Article