Inhibition of SARS-CoV-2 replication by zinc gluconate in combination with hinokitiol
히노키티올과 함께 글루콘산아연에 의한 SARS-CoV-2 복제 억제
Article
[키워드] 3CLpro
acute respiratory syndrome coronavirus
antiviral therapy
approach
binding
catalytic site
chymotrypsin
Combination
Concentration
coronavirus 2
coronavirus disease
Coronavirus disease 2019
Coronavirus infections
COVID-19
elevated
Enzyme inhibition
exhibited
experimental evidence
global public health
gluconate
hinokitiol
in vitro
inhibit
inhibited
inhibition
inhibitory
Ionophore
mammalian cells
metal ion
MPro
pandemic
Papain
Papain-like protease
PLPro
potential benefit
potential benefits
protease
Protease activity
Proteases
protein structure
proteolytic
proteolytic activity
residues
respiratory
SARS-CoV-2
SARS-CoV-2 replication
screened
Severe acute respiratory syndrome
severe acute respiratory syndrome coronavirus 2
significantly
small molecule
target
Treatment
Zinc
zinc gluconate
Zinc gluconate.
[DOI] 10.1016/j.jinorgbio.2022.111777 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.jinorgbio.2022.111777 PMC 바로가기 [Article Type] Article