Cardiovascular magnetic resonance evaluation of soldiers after recovery from symptomatic SARS-CoV-2 infection: a case–control study of cardiovascular post-acute sequelae of SARS-CoV-2 infection (CV PASC)증상이 있는 SARS-CoV-2 감염에서 회복된 군인의 심혈관 자기 공명 평가: SARS-CoV-2 감염(CV PASC)의 심혈관 급성 후유증에 대한 증례-대조군 연구Research Published on 2021-10-072022-09-10 Journal: Journal of Cardiovascular Magnetic Resonance [Category] MERS, SARS, 치료기술, [키워드] 1:1 Acute myocarditis acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 acute SARS-CoV-2 infection age Asymptomatic Athletes athletic cardiac death Cardiopulmonary cardiovascular Cardiovascular Symptoms characterization Chi-squared tests Clinical diagnosis Control control group controls convalescent phase coronavirus COVID-19 criteria Critical death demographic determine diagnosed Diagnosis dysfunction Ejection fraction enrolled etiology evaluate Follow-up gadolinium Gender groups healthy Hospitalization imaging parameters Infection insertion Isolated Laboratory Lake majority median median time moderate moderate symptoms myocarditis occur occurred parameter PASC pathology phenotype progression reported required respiratory Result return Return-to-service SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection septal service severe acute respiratory syndrome Coronavirus Soldiers Spectrum Sports Cardiology sudden cardiac death Symptom symptomatic Takotsubo cardiomyopathy variables ventricular was reduced were used Wilcoxon rank sum [DOI] 10.1186/s12968-021-00798-1 PMC 바로가기 [Article Type] Research
Evolving phenotypes of non-hospitalized patients that indicate long COVIDResearch Article Published on 2021-09-272022-10-28 Journal: BMC Medicine [Category] COVID-19, [키워드] 95% CI acute phase Adults age age and gender analyses analysis Anosmia applied Area Boston cause characterized chest pain chronic fatigue syndrome Clinical data Cohort cohort study COVID COVID-19 COVID-19 infection Diabetes Mellitus diagnoses Diagnosis Effects effort EHR Electronic health records evaluated Health Healthcare system help Hospitalized identify Infection knowledge machine learning mass Neurological disorder participant PASC Patient patients patients’ medical record performed phenotype Phenotypes Pneumonia positive Post-acute sequelae of SARS-CoV-2 recorded Research resource Result retrospective risk RT-PCR RT-PCR test SARS-CoV-2 SARS-COV-2 infection Shortness of breath supplementary material Survivors Symptom tested type 2 diabete vaccination variety was used [DOI] 10.1186/s12916-021-02115-0 PMC 바로가기 [Article Type] Research Article
Long-COVID: Langzeitsymptome und morphologische/radiologische KorrelateLeitthema Published on 2021-09-232022-10-29 Journal: Der Radiologe [Category] COVID-19, MERS, SARS, [키워드] Coronavirus diseases 2019 Coronavirus-Krankheit 2019 COVID-19 Delayed sequelae long haulers PASC phase Post-acute symptoms Postakute Symptome SARS-CoV‑2 Screening Spätfolgen [DOI] 10.1007/s00117-021-00910-7 PMC 바로가기 [Article Type] Leitthema
Development of ACE2 autoantibodies after SARS-CoV-2 infectionSARS-COV-2 감염 후 ACE2자가 항체의 발달Research Article Published on 2021-09-032022-08-13 Journal: PLoS ONE [Category] Biochemistry, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] abundance ACE2 ACE2 antibody ACE2 protein Activation Ang II angiotensin Angiotensin II Angiotensin-converting enzyme angiotensin-converting enzyme 2 Anti-spike antibodies antibody AT1 autoantibodies autoantibody cause cleave convalescent Cutoff decrease decreased activity detectable develop development enzyme enzyme activity exogenous ACE2 Hospitalized Hypothesis immune system implicated increase in Infection inhibit lead less mechanism Outpatient PASC Patient plasma positive PCR test proinflammatory Protein receptor resulting SARS-CoV-2 SARS-COV-2 infection serum soluble ACE2 Symptom tested threshold Trigger triggers [DOI] 10.1371/journal.pone.0257016 PMC 바로가기 [Article Type] Research Article
Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin장기간 COVID-19/PASC(Post-Acute Sequelae of COVID-19)의 지속적인 응고 단백질 병리는 항플라스민 수치 증가를 동반합니다Original Investigation Published on 2021-08-232022-09-10 Journal: Cardiovascular Diabetology [Category] MERS, SARS, 진단, 치료기술, [키워드] accompanied acute COVID-19 acute infection acute respiratory syndrome acute respiratory syndrome coronavirus amyloid A Antiplasmin Anxiety benefit blood clot Blood clots breath characterized circulating clinical pathologies clotting Coagulopathies Coagulopathy Control control sample coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 phenotype Depression diabetes digested fatigue Fibrin(ogen) fibrinogen fibrinolysis fibrinolytic system fluorescence microscopy healthy individuals Hypercoagulation increase in individual Infection Inflammatory inhibit Long Long COVID/PASC Microclots muscle weakness oxygen oxygen exchange PASC Pathologies pathology Patient pellet persistent plasma plasma sample plasma samples platelet hyperactivation Protein proteomics regime respiratory Result SAA serum amyloid A severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 supernatant Support survivor Symptom Symptoms syndrome therapy Type Type 2 diabetes mellitus Volume weakness [DOI] 10.1186/s12933-021-01359-7 PMC 바로가기 [Article Type] Original Investigation
Implications of Innate Immunity in Post-Acute Sequelae of Non-Persistent Viral InfectionsReview Published on 2021-08-192022-10-31 Journal: Cells [Category] COVID-19, MERS, [키워드] Activation Acute acute infection acute phase Anti-viral chronic Chronic fatigue chronic inflammation condition COVID COVID-19 Cytokines defined disorders dysregulated immune response evade highlight immune response in some Infection Inflammation Influenza Innate innate immune Innate immunity interferon Long COVID long hauler syndrome Neurological complication PAS PASC pathogen patients Perspective post-acute Post-acute sequelae reported resulting signaling pathway Symptom the patient Treatment triggering viral infections viral pathogen virus virus viruses [DOI] 10.3390/cells10082134 PMC 바로가기 [Article Type] Review
Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms급성 후 증상이 있거나 없는 COVID-19에서 회복하는 개인의 장기 SARS-CoV-2 특이적 면역 및 염증 반응Article Published on 2021-08-102022-09-11 Journal: Cell Reports [Category] MERS, SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody antibody levels CD107a CD4 CD8 coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 degranulation expressing Frequency immune immune response immune responses Immunity individual Infection Inflammation Inflammatory response initial Long COVID Lung disease magnitude marker neutralization capacity observé participant PASC PCR-confirmed peptide peptide pool post-acute sequelae of SARS-CoV-2 infection. recovering from COVID-19 respiratory Saliva SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severity Spectrum Symptom symptom onset T cell T cell response T cell responses T cells Viral viral shedding [DOI] 10.1016/j.celrep.2021.109518 PMC 바로가기 [Article Type] Article
Duration of post–COVID-19 symptoms is associated with sustained SARS-CoV-2–specific immune responses코로나19 이후 증상의 지속 기간은 지속적인 SARS-CoV-2 특정 면역 반응과 관련이 있습니다.Research Article Published on 2021-08-092022-09-12 Journal: JCI Insight [Category] MERS, SARS, 진단, [키워드] Adaptive immunity antibody Antigen CD4 cell population circulating correlation COVID-19 COVID-19 patient COVID-19 symptom COVID-19 symptoms demonstrated Duration etiology evaluated expected follicular groups helper cell IgG immune cell types immune response immune responses immune signature immunology individual investigated magnitude marker median PASC Patient Peripheral blood persistence phenotypic resolved SARS-COV-2 infection SARS-CoV-2 spike protein Significant Spike protein subset sustained Symptom symptom duration symptom resolution systemic inflammation T cell T cell response T cells Viral antigen viral antigens [DOI] 10.1172/jci.insight.151544 PMC 바로가기 [Article Type] Research Article
Post-acute sequelae of COVID-19 in a non-hospitalized cohort: Results from the Arizona CoVHORTResearch Article Published on 2021-08-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] average Brain clinical COVID COVID-19 COVID-19 test days post-infection defined fatigue female Follow-up hospitalized COVID-19 patient individual individual symptoms median moderate MOST number of symptom outcomes participant PASC population-based cohort positive Prevalence ranged Research Result SARS-CoV-2 severe disease Symptom Symptoms used data while [DOI] 10.1371/journal.pone.0254347 PMC 바로가기 [Article Type] Research Article
Serum Metabolic Profile in Patients With Long-C ovid (PASC) Syndrome: Clinical ImplicationsMedicine Published on 2021-07-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] albumin alteration Anti-inflammatory anticoagulant therapy Blood clinical clinical conditions clinically Coagulation Concentration concomitant disease COVID-19 CRP D-dimer Dyspnea Elevation erythrocyte sedimentation rate evaluated fatigue ferritin hemoglobin hospital discharge implicated indicated Inflammation knowledge LDH Long-COVID-syndrome Long-term follow-up maintain marker metabolic metabolism molecular muscular PASC pathophysiology Patient patient symptom patients persistence profile Prophylactic Protein raise rehabilitation reported risk SARS-COV-2 infection SARS-CoV2 selected serum Seven Symptom syndrome thromboembolic disease virus infection weakness [DOI] 10.3389/fmed.2021.714426 PMC 바로가기 [Article Type] Medicine