The impact of the COVID-19 pandemic on lifestyle behaviors in children and adolescents: an international overviewReview Published on 2022-02-042022-10-29 Journal: Italian Journal of Pediatrics [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] adverse effect children coronavirus 2 coronavirus disease COVID-19 COVID-19 and children COVID-19 and lifestyle COVID-19 and nutrition COVID-19 pandemic deficiencies deleterious effect effective effort greater immune system include increased risk indirect effects Infectious disease International lack Malnutrition mental health nutritional need offer pandemic Pediatrician physical resources respiratory risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infection and children Side effect social isolation stimulate Support targeted therapy [DOI] 10.1186/s13052-022-01211-y PMC 바로가기 [Article Type] Review
An observational study of hospitalized COVID-19 patients with cancer in San Diego countyObservational Study Published on 2022-02-022022-10-04 Journal: Future Oncology [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] accumulating Admission Analysis anti-cancer treatment association Cancer cancer patient Cancer patients Chemotherapy Clinical characteristics clinical feature conducted covariate covariates COVID-19 COVID-19 infection COVID-19 severity death determine diagnosis of cancer diagnosis of COVID-19 Diego disease Evidence greater hematologic Hematologic malignancy heterogenous hospital Hospitalized hospitalized COVID-19 patient hospitalized patient Immunotherapy incidence inclusion criteria increased mortality Laboratory lung lung cancer lung involvement lung metastasis malignancy metastatic tumor morbidity and mortality Mortality multivariate logistic regression Odds ratio outcome Patient patients positive presenting receiving retrospective SARS-CoV-2 severity significantly increased solid tumor statistically significant susceptibility systemic anti-cancer therapy targeted therapy therapy Treatment were used with COVID-19 [DOI] 10.2217/fon-2021-1116 PMC 바로가기 [Article Type] Observational Study
Pulmonary artery targeted therapy in treatment of COVID-19 related ARDS. Literature reviewReview article Published on 2022-02-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] 치료법, 치료제, [키워드] acute respiratory distress antagonists antiviral property Apoptosis appear ARDS Blood blood pressure bosentan Combination COVID-19 COVID-19 associated ARDS database decrease Deterioration drug Endothelin Endothelin receptor antagonists Epoprostenol Google Scholar help IMPROVE Infection inhibit inhibitors investigated literature lung Lung epithelial cells lung lesion Meta-analysis oedema Oxygenation PAH Patient PDE-5 inhibitors prostacyclin pulmonary arterial hypertension pulmonary artery Randomized controlled trials receptor reduce Respiratory function Result Riociguat Severe case severe SARS-CoV-2 syndrome synergism targeted therapy therapy Treatment ventilation/perfusion [DOI] 10.1016/j.biopha.2021.112592 [Article Type] Review article
Antineoplastic treatment class modulates COVID-19 mRNA-BNT162b2 vaccine immunogenicity in cancer patients: a secondary analysis of the prospective Vax-On study항암제 치료 클래스는 암 환자에서 COVID-19 mRNA-BNT162b2 백신 면역원성을 조절합니다: 전향적 Vax-On 연구의 2차 분석Article Published on 2022-02-012022-09-12 Journal: ESMO open [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] accounted Analysis antibody Antibody Response Antineoplastic Cancer cancer treatment carried Chemotherapy classification Cooperative correlated correlation Corticosteroid COVID-19 COVID-19 vaccination COVID-19 vaccine Cytotoxic chemotherapy defined DNA dose drug Effect enrolled granulocyte group humoral IgG Immunoglobulin immunosuppressive inhibitor inhibitors Interaction intravesical lack modulate mTOR inhibitor Patient performance status predicted Rapamycin Receptor binding domain reduced retained second dose Seroconversion seroconversion response significantly significantly lower Specific Spike protein subgroup subgroup analysis subgroups targeted therapy the S1 subunit the SARS-CoV-2 therapy TKI TKIs treated Treatment tyrosine kinase inhibitor Vaccine vaccine immunogenicity Variation [DOI] 10.1016/j.esmoop.2021.100350 PMC 바로가기 [Article Type] Article
HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management Reviews Published on 2022-02-012022-10-05 Journal: Nature Reviews Clinical Oncology [Category] 바이오마커, [키워드] addition Cancer Care Cell Clinical course Clinical management diagnostic biomarker disease effort Epidemiology greater highlight Human identify Immunotherapy IMPROVE incidence individuals lack molecular basis Molecular biology ongoing trial Oropharyngeal outcomes Patient Precision Prevalence Prognosis Quality of life review survival Symptom targeted therapy Treatment [DOI] 10.1038/s41571-022-00603-7 [Article Type] Reviews
Antigen Specific Humoral and Cellular Immunity Following SARS-CoV-2 Vaccination in ANCA-Associated Vasculitis Patients Receiving B-Cell Depleting TherapyB 세포 고갈 요법을 받는 ANCA 관련 혈관염 환자에서 SARS-CoV-2 백신 접종 후 항원 특이적 체액 및 세포 면역Immunology Published on 2022-01-282022-09-11 Journal: Frontiers in Immunology [Category] 진단, 치료법, [키워드] ANCA-associated vasculitis anti-CD20 anti-CD20 therapy anti-SARS-CoV-2 Anti-spike antibody assays B-cell B-cells cellular Cellular immune response characterized control subjects controls COVID-19 vaccination elicit ELISPOT enzyme-linked immunosorbent humoral humoral immune response Humoral response immune responses immunoassays interferon lack mounted Patient patients peptide peptide pool positive Protective protective effect receiving Receptor binding domain recovered patient Research response rituximab robust S glycoprotein SARS-CoV-2 SARS-CoV-2 vaccination Specific Specific T-cell response subject subjects subunit T-cell immunity T-cell Response T-cell responses targeted therapy vaccination Vaccine vaccine response Vasculitis were measured [DOI] 10.3389/fimmu.2022.834981 PMC 바로가기 [Article Type] Immunology
Matrix metalloproteinases (MMP) 3 and 9 as biomarkers of severity in COVID-19 patientsCOVID-19 환자의 중증도 바이오마커로서의 기질 금속단백분해효소(MMP) 3 및 9Clinical Trial Published on 2022-01-242022-09-10 Journal: Scientific Reports [Category] 바이오마커, 임상, 진단, 치료법, [키워드] benefit Biomarker Biomarkers circulating neutrophil circulating neutrophils clinical heterogeneity contribute controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 severity disease severity Diseases Health Organization help Hospital admission Hospitalization hospitalized patient immunology inflammatory process interleukin-6 lung damage Lung inflammation matrix matrix metalloproteinases Medical research metalloproteinase MMP3 MMP9 molecular basis monocyte Monocytes myeloperoxidase Neutrophils no correlation occur pathogenic positively correlated Potential biomarker potential biomarkers predict progression Protein Proteins regeneration serum Serum level serum levels severe COVID-19 patient severe COVID-19 patients severe patients severity severity of COVID-19 significantly increased targeted therapy the WHO to define was increased was reduced WHO World Health Organization [DOI] 10.1038/s41598-021-04677-8 PMC 바로가기 [Article Type] Clinical Trial
Insights Into the Changing Landscape of Coronavirus Disease 2019Cellular and Infection Microbiology Published on 2022-01-102022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome caused Changing China clinical manifestation confirmed case connection contagious coronavirus Coronavirus disease 2019 COVID epidemiology COVID origin COVID treatment COVID-19 death disease Epidemiology genetics global pandemic highlight Infectious disease insight landscape management pandemic pathology Personalized medicine reported SARS-CoV-2 targeted therapy Treatment World Health Organization Wuhan [DOI] 10.3389/fcimb.2021.761521 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Immunogenicity of COVID-19 Vaccination in Melanoma Patients under Immune Checkpoint Blockade면역관문 봉쇄하에 있는 흑색종 환자에서 코로나19 예방접종의 면역원성Article Published on 2022-01-012022-09-12 Journal: Oncology [Category] SARS, 진단, [키워드] Advanced melanoma Analysis anti-SARS-CoV-2 spike protein antibody Antibody Response Blood cancer patient Care center comparable COVID-19 COVID-19 vaccination COVID-19 vaccine described ELISA ENhance expected Germany Hanover Health healthy humoral immune response IgG antibodies Immune checkpoint inhibitors immune response immunogenicity independent influenza vaccines inhibitor median Melanoma observé Patient professionals Quantitative recruited SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine significantly higher skin study population targeted therapy the timing therapy Treatment vaccination was performed weakened immune system [DOI] 10.1159/000524894 PMC 바로가기 [Article Type] Article
Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applicationsSARS-CoV-2 유발 질환의 인터루킨-6: 상호작용 및 치료적 적용Review Published on 2022-01-012022-09-12 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome Angiogenesis anti-inflammatory activity blockade C-reactive protein C-reactive protein (CRP C-reactive protein (CRP) Cancer cancer patient chronic inflammation Complete complex Concentration coronavirus cytokine Cytokine storm determine disease effective event hyperinflammation Hypoxemia hypoxia IL-6 IL-6 inhibition IL-6 levels increase Inflammation Interaction Interleukin-6 (IL-6) lymphopenia multi-organ failure Patient patient with SARS-CoV-2 patients with SARS-CoV-2 pleiotropic Pneumonia promote representing SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulatory Taking targeted therapy the SARS-CoV-2 therapeutic therapy Tocilizumab [DOI] 10.1016/j.biopha.2021.112419 PMC 바로가기 [Article Type] Review