Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infectionSARS-CoV-2 감염에 대한 신경모세포종 및 교모세포종 세포주의 감수성Article Published on 2021-05-012022-09-11 Journal: Brain research [Category] SARS, 치료기술, [키워드] Analysis Apoptosis Cell cell line cell lines cell type cells Coronavirus-2 CTSB CTSL Cytopathic effect death demonstrated described downregulation epithelial cell epithelial cells Express Gene Expression Genes Glioblastoma Glutamate idea In situ hybridization infected cell infected cells Infection maintain MOI MOIs Neuroblastoma neuronal neurotropism Perspective quantification replicate retinoic acid RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 SH-SY5Y susceptibility tropism upregulation Vero E6 VERO E6 cells virus were expressed were infected [DOI] 10.1016/j.brainres.2021.147344 PMC 바로가기 [Article Type] Article
Physical activity, screen exposure and sleep among students during the pandemic of COVID-19Article Published on 2021-04-202022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] activity change Chi-square children’s health Chinese conducted COVID-19 pandemic cross-sectional determine Diseases Effect Gender groups Guangzhou, China health-related behaviour highest Inadequate indicated less median age moderate over pandemic pandemic of COVID-19 per day percentage physical activity proportion questionnaire Region reported Risk factors School Schools screen time stratified student was used were expressed [DOI] 10.1038/s41598-021-88071-4 PMC 바로가기 [Article Type] Article
AP205 VLPs Based on Dimerized Capsid Proteins Accommodate RBM Domain of SARS-CoV-2 and Serve as an Attractive Vaccine CandidateArticle Published on 2021-04-192022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] activities aggregate aggregates Analysis antibody AP205-VLPs C terminus candidate capsid caused Convalescent patients COVID-19 denatured dimerized disease displaying domain E. coli expressed fused generate Health humoral immune response IgG antibody immunization immunized mice Impact insoluble Microscopy neutralize neutralizing antibody pandemic produced Proteins RB motif RBD RBM Receptor binding domain receptor binding motif recognizing resulting SARS-CoV-2 Spike protein urea vaccination vaccine candidate virus-like particles VLP were expressed [DOI] 10.3390/vaccines9040403 PMC 바로가기 [Article Type] Article
Excess All-Cause Deaths during Coronavirus Disease Pandemic, Japan, January–May 2020 1Research Published on 2021-03-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] age all-cause deaths Analysis applied consequence coronavirus disease COVID-19 death deaths estimate excess excess deaths expected indicated Japan Mortality National pandemic Regression model reported respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 viruses were expressed zoonoses [DOI] 10.3201/eid2703.203925 PMC 바로가기 [Article Type] Research
ACE2 & TMPRSS2 Expressions in Head & Neck Tissues: A Systematic Review두경부 조직에서의 ACE2 및 TMPRSS2 발현: 체계적인 검토Article Published on 2021-03-012022-09-11 Journal: Head and Neck Pathology [Category] SARS, 치료기술, [키워드] ACE2 ACE2 expression acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age anatomical angiotensin angiotensin converting enzyme Angiotensin converting enzyme-2 animal cell type cell types Cochrane Library conducted coronavirus Coronavirus-2 COVID detect endothelial cells expressed expression goblet Google Scholar head Head Neck heterogeneity Host Human inclusion criteria independent Intervention investigator medRxiv mucosa Neck olfactory Olfactory region organism outcome pandemic pharyngeal protease respiratory cells review salivary SARS-CoV-2 SARS-CoV-2 receptors searched Serine Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus stem cells suggested tissue tissues TMPRSS2 TMPRSS2 expression transmembrane viral entry were expressed were used [DOI] 10.1007/s12105-020-01212-5 PMC 바로가기 [Article Type] Article
Features of patients that died for COVID-19 in a hospital in the south of Mexico: A observational cohort studyObservational Study Published on 2021-02-192022-10-04 Journal: PLoS ONE [Category] MERS, 임상, [키워드] age Clinical characteristics Cluster Comorbidity COVID-19 death Deceased diabete diagnose died drug dry cough Dyspnea evaluate feature Features Fever Frequency hospital Hydroxychloroquine hypertension individual individuals with COVID-19 information male mean hospital stay medical records number of infected obesity Observational cohort study off-label oseltamivir overlapping Patient performed pharmacological treatment present Prevalence proportion Result retrieved risk of death SARS-CoV2 Shortness of breath Spread Standard deviation Symptom treating COVID-19 Treatment Venn diagrams were expressed [DOI] 10.1371/journal.pone.0245394 PMC 바로가기 [Article Type] Observational Study
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapyArticle Published on 2021-02-062022-10-30 Journal: iScience [Category] COVID-19, [키워드] Abstract acute respiratory syndrome Analysis Biological Biological sciences Calu-3 coronavirus COVID-19 Disease progression elicited epithelial cell line epithelial cells expression gene expression profile Genes Heat shock host responses Hsp90 human cell line human cell lines identify IL-6 impair infected cell infected cells Infection inhibition inhibitor innate immune response interferon interferon regulatory factor knowledge Molecular biology NF-kB nuclear omics primary human airway pro-inflammatory cytokine pro-inflammatory gene Protein reduction RNA sequencing SARS-CoV SARS-CoV-2 subset suggested target gene Temporal therapy transcriptional activity transcriptomics upregulated viral replication Virology virus infection were expressed [DOI] 10.1016/j.isci.2021.102151 PMC 바로가기 [Article Type] Article
Frequency and characterization of ancillary chest CT findings in COVID-19 pneumoniaFull Paper Published on 2021-02-012022-10-27 Journal: The British Journal of Radiology [Category] COVID-19, [키워드] 95% confidence interval acute respiratory syndrome Admission advance association Chest CT Clinical data consolidation Continuous cough COVID-19 CT chest described disease disease severity feature Fever help heterogeneous High-resolution CT Hospital stay intensive care lower oxygen saturation Lymph node lymph nodes Mann–Whitney U test mechanism median nodule nodules oxygen saturation parameters Patient Pneumonia polymerase chain Prevalence respiratory rate subpleural tested to define transcriptase Typical vessel Viral pneumonia were excluded were expressed [DOI] 10.1259/bjr.20200716 PMC 바로가기 [Article Type] Full Paper
Frequency and characterization of ancillary chest CT findings in COVID-19 pneumoniaFull Paper Published on 2021-02-012022-10-27 Journal: The British Journal of Radiology [Category] Coronavirus, COVID-19, MERS, [키워드] 95% confidence interval acute respiratory syndrome Admission advance association Chest CT Clinical data consolidation Continuous cough COVID-19 CT chest described disease disease severity feature Fever help heterogeneous High-resolution CT Hospital stay intensive care lower oxygen saturation Lymph node lymph nodes Mann–Whitney U test mechanism median nodule nodules oxygen saturation parameters Patient Pneumonia polymerase chain Prevalence respiratory rate subpleural tested to define transcriptase Typical vessel Viral pneumonia were excluded were expressed [DOI] 10.1259/bjr.20200716 PMC 바로가기 [Article Type] Full Paper
Frequency and characterization of ancillary chest CT findings in COVID-19 pneumoniaCOVID-19 폐렴에서 보조 흉부 CT 소견의 빈도 및 특성Full Paper Published on 2021-02-012022-09-12 Journal: The British Journal of Radiology [Category] 진단, [키워드] 95% confidence interval acute respiratory syndrome Admission advance association Atelectasis Chain Reaction Chest CT Clinical data Clinical parameters consolidation Continuous Continuous data coronavirus disease Coronavirus disease-19 cough COVID-19 COVID-19 pneumonia CT chest described disease disease severity feature Fever ground-glass opacity help heterogeneous High-resolution CT Hospital stay intensive care intensive care unit admission lower oxygen saturation Lymph node lymph nodes Mann–Whitney U test mechanism median mediastinal lymph nodes negative RT-PCR nodule nodules oxygen oxygen saturation parameters Patient pericardial effusion pleural effusion Pneumonia polymerase chain polymerase chain reaction Prevalence respiratory respiratory rate reverse transcriptase RT-PCR Severe acute respiratory syndrome subpleural tested to define transcriptase Typical vessel Viral Viral pneumonia were excluded were expressed [DOI] 10.1259/bjr.20200716 PMC 바로가기 [Article Type] Full Paper