cause – Page 69 – Communicable Diseases Research

Neurological complications and infection mechanism of SARS-CoV-2

SARS-CoV-2의 신경학적 합병증 및 감염 기전

Review

Published on 2021-11-232022-09-12
Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 진단, 치료제,

SARS‐CoV‐2 N Protein Induces Acute Kidney Injury via Smad3‐Dependent G1 Cell Cycle Arrest Mechanism

SARS -COV -2 N 단백질은 SMAD3- 의존적 G1 세포주기 정지 메커니즘을 통해 급성 신장 손상을 유도합니다.

Research Article

Published on 2021-11-232022-09-10
Journal: Advanced Science [Category] MERS, SARS, 유전자 메커니즘, 치료법,

[키워드] activate Acute kidney injury acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 AKI arrest cause Cell cell cycle cell cycle arrest cell death coronavirus COVID‐19 COVID‐19 patients Critically ill cycle death Deletion develop ENhance epithelial epithelial cell G1 cell cycle identify in vitro in vivo induce inhibit inhibitor kidney knockout mice mechanism mediator mice MOST N protein organ organ injury overexpressing p21 pharmacological PROTECT respiratory SARS‐CoV‐2 SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus Signaling significantly Smad3 target organs targeting TGF‐β therapy Treatment
[DOI] 10.1002/advs.202103248 PMC 바로가기 [Article Type] Research Article

COVID-19 Pandemic: Public Health Risk Assessment and Risk Mitigation Strategies

Review

Published on 2021-11-232022-10-30
Journal: Journal of Personalized Medicine [Category] COVID-19,

Phased Return of Students to 77 Transitional Kindergarten-8th Grade Schools With Cohesive Mitigation Strategies Serving as Protective Factors Against the Increase of COVID-19 Cases in Marin County: September 2020-January 2021

Infectious Disease

Published on 2021-11-222022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] acute respiratory syndrome Against Analysis approval cause children Community conducted Contact tracing contrary coronavirus coronavirus disease correlation COVID-19 COVID-19 case COVID-19 incidence covid-19 school protocols COVID-19 transmission Critical Department determine driver education education equity effective mask wearing epidemiological Factor GRADE Guidance Human implication in-person learning incidence rate increase increase in IRB material Mitigation nine office over pandemic participant pediatric pediatric quarantine/isolation performed public health recommendations reduced Result return returned safe school reopening SARS-CoV-2 transmission SARS‐CoV‐2 School school health service significantly Strategy student subject Surveillance Transmission Viral transmission virus
[DOI] 10.7759/cureus.19821 PMC 바로가기 [Article Type] Infectious Disease

Clinical and Laboratory Factors in Predicting Mortality Among COVID-19 RT-PCR Positive Patients: A Retrospective Observational Study From a Tertiary Care Center

Internal Medicine

Published on 2021-11-212022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] Acute kidney injury acute respiratory distress acute respiratory distress syndrome [ards] addition age age and sex AKI albumin analyzed Aspartate aminotransferase AST C-reactive protein (CRP Cardiac arrest carried categorical variable cause center clinical clinical and laboratory characteristics co-morbidities co-morbidity complications condition control group coronavirus disease coronavirus disease (COVID-19) Corticosteroids COVID-19 COVID-19 infection CRP D-dimer death diabetes Factor Frequency Gender higher odds hypertensive IL-6 independent risk factor information Intervention laboratory parameter lactate dehydrogenase LDH Lymphocytes lymphopenia mechanically ventilated medical records Monocytes Mortality Mortality predictors multivariable logistic regression nasal neurological Neutrophils non-survivor outcome Oxygen therapy patients with COVID-19 positive COVID-19 Prevent procalcitonin raised Randomly Result retrospective risk factor risk stratification RT-PCR selected serum creatinine severity shown significantly statistically survivor syndrome Tertiary Tocilizumab univariable was collected were expressed were used
[DOI] 10.7759/cureus.19791 PMC 바로가기 [Article Type] Internal Medicine

Predictors of Mortality in COVID-19-Positive Patients On and Off CPAP: A Review From a Tertiary Care Setting in the NHS

Internal Medicine

Published on 2021-11-202022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] affected affecting age Analysis cause collected consolidation coronavirus disease correlated Course COVID-19 COVID-19 patient CPAP creatinine diagnosed with COVID-19 England expired Final help identify inclusion criteria increased mortality Intubated James Cook lung lung involvement management Medical Research Council Mortality negative RT-PCR NHS objective Off outbreak pandemic Patient PCR test performance status Pneumonia positive airway pressure predictor predictors receiving respiratory rate Result review RT-PCR SARS-CoV-2 setting significantly small sample size Tertiary the disease the patient university virus were excluded
[DOI] 10.7759/cureus.19762 PMC 바로가기 [Article Type] Internal Medicine

Comparative genomic analysis reveals varying levels of mammalian adaptation to coronavirus infections

비교 게놈 분석은 코로나 바이러스 감염에 대한 다양한 수준의 포유류 적응을 보여줍니다.

Comparative Study

Published on 2021-11-182022-09-10
Journal: PLoS Computational Biology [Category] MERS, SARS, 바이오마커, 유전자 메커니즘,

[키워드] 229E ACE2 ACE2 protein ACE2 proteins acting adaptation adaptive Affect Amino acid amino acid substitution amino acid substitutions aminopeptidase aminopeptidase N Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Animal host APN bats binding causative agent cause caused cellular receptor Chinese Chinese Horseshoe bats clade class common cold Comparative coronavirus Coronavirus infection Coronaviruses COVID-19 Evidence evidence of Evolution genomic Genomic analysis HCoV HCoV-229E Health horseshoe horseshoe bats Host host receptor host susceptibility hosts human coronavirus human coronavirus 229E Interaction Lineage lineages mammal mammalian pathogen Pathogens pattern Phylogeny primates Protein receptor Research reservoir resistance to infection resistance to infections respiratory Respiratory Coronavirus reveal rodent rodents SARS-CoV SARS-CoV-2 SARS-CoV-2 spike protein SARS-like coronaviruses SARS-like virus SARS-like viruses severe acute respiratory coronavirus severe acute respiratory coronavirus 2 severity of symptom shown species Spike protein susceptible symptomatic disease the SARS-CoV-2 these viruses Tolerance Variation Viral viral entry viral infection viral infections Viral vector virus viruses zoonotic origin
[DOI] 10.1371/journal.pcbi.1009560 PMC 바로가기 [Article Type] Comparative Study

A coarse‐refine segmentation network for COVID‐19 CT images

Original Research Paper

Published on 2021-11-182022-10-30
Journal: Iet Image Processing [Category] COVID-19,

[키워드] added cause COVID‐19 COVID‐19 patient COVID‐19 patients Critical diagnose effective Experimental result IMPROVE Infection novel coronavirus disease outperform predict progression public health receive Region Spread Structure Treatment
[DOI] 10.1049/ipr2.12278 PMC 바로가기 [Article Type] Original Research Paper

Estimation of viral kinetics model parameters in young and aged SARS-CoV-2 infected macaques

Mathematics

Published on 2021-11-172022-10-28
Journal: Royal Society Open Science [Category] COVID-19,

Systemic Lupus Erythematosus With Hemophagocytic Lymphohistiocytosis: Is COVID-19 the Inciting Factor?

Infectious Disease

Published on 2021-11-172022-10-31
Journal: Cureus [Category] COVID-19,