Diagnostic Efficacy and Tolerability of Molded Plastic Nasopharyngeal Swab (FinSwab) Compared to Flocked Nylon Swab in Detection of SARS-CoV-2 and Other Respiratory VirusesSARS-CoV-2 및 기타 호흡기 바이러스의 검출에서 플록 나일론 면봉과 비교한 성형 플라스틱 비인두 면봉(FinSwab)의 진단 효능 및 내약성Comparative Study Published on 2021-10-202022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, [키워드] age analyzed assays clinical setting collected comparable Copan coronavirus COVID-19 COVID-19 infection cycle threshold detection deviation diagnostic diagnostics discomfort Efficacy equipment evaluate Italy mRNA nasopharyngeal nasopharyngeal sample nasopharyngeal sampling Nasopharyngeal swab nasopharyngeal swabs no difference nostril Nylon OC43 Other Other respiratory viruses Patient patients plastic plastic injection molding positive Randomized respiratory respiratory virus respiratory viruses reverse transcriptase reverse transcriptase PCR rhinovirus RT-PCR sampling SARS-CoV-2 Spread subset supply Swab swabs symptomatic Tolerability virus β-actin [DOI] 10.1128/Spectrum.00736-21 PMC 바로가기 [Article Type] Comparative Study
Automated ELISA On-Chip for the Detection of Anti-SARS-CoV-2 AntibodiesAnti-SARS-CoV-2 항체 검출을 위한 자동화된 ELISA 온칩Communication Published on 2021-10-132022-09-10 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 진단, 치료기술, [키워드] Analysis analyzed anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibodies automated caused ChIP clinical setting COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients crisis Critical deficiencies demonstrated described detection ELISA equipment identify Image analysis Laboratory methodology Microfluidics microplate reader mitigate on-chip public health reaction SARS-CoV-2 SARS-CoV-2 antibodies serological test Serological tests serology serum sample serum samples significantly Smartphone Spike protein statistically significant difference vaccinated individuals vaccination worsened [DOI] 10.3390/s21206785 PMC 바로가기 [Article Type] Communication
Development of a Multiplex Tandem PCR (MT-PCR) Assay for the Detection of Emerging SARS-CoV-2 Variants신흥 SARS-COV-2 변이체의 검출을위한 멀티 플렉스 탠덤 PCR (MT-PCR) 분석의 개발Communication Published on 2021-10-082022-09-01 Journal: Viruses [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] absence Alpha Applying approach B.1.1.7 B.1.1.7 lineage Chain Reaction clinical isolates clinical setting Concordance defined detection development evaluated example facilitated FIVE Genome sequencing genomic hospital identify in vitro diagnostic test information international public health isolate K417 Lineage Mutation National nucleic acid nucleotide P681 PCR polymerase chain polymerase chain reaction polymorphism Polymorphisms presence or absence Public health responses reference strain S gene SARS-CoV-2 SARS-CoV-2 lineage Sequence analysis Sequencing single nucleotide Single nucleotide polymorphism SNP tandem turnaround time UK hospital utilised variant variants variants of SARS-CoV-2 [DOI] 10.3390/v13102028 PMC 바로가기 [Article Type] Communication
A Virtual Approach to Promote Inter-Professional Learning (IPL) Between Biomedical Science and Medicine in Higher Education for the Benefit of Patient CarePublic Health Published on 2021-10-062022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] addition Analysis Biomedical science clinical setting cross-discipline collaboration diagnosing Diagnosis disease education effective healthcare healthcare professionals healthcare professions interprofessional education (IPE) Interprofessional learning Laboratory learning majority Medic Medicine nine outcome pandemic participant pathology Patient care Perspective platform positive professional provided Regulatory reported Science scientist similarity supported university virtual education [DOI] 10.3389/fpubh.2021.747751 PMC 바로가기 [Article Type] Public Health
In silico drug repurposing in COVID-19: A network-based analysisCovid-19의 Silico Drug Reperhing에서 : 네트워크 기반 분석Article Published on 2021-10-012022-08-31 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] MERS, 신약개발, 임상, 치료제, [키워드] addition Analysis analyzed antibodies Anticoagulants approach Blood cells bowel Central nervous system clinical clinical setting clinical trial clinical trials compounds conditions Corticosteroid Corticosteroids corticosteroids) COVID-19 COVID-19 patient COVID-19 patients de novo drug Drug discovery Drug repurposing examined faster healthy subjects heparin identify Inflammatory bowel disease inhibitor mandatory patients with COVID-19 priority public health emergency SARS-CoV-2 pandemic SCN5A septic Septic shock Shock transcriptomic data treat vaccination whole blood cell whole blood cells [DOI] 10.1016/j.biopha.2021.111954 PMC 바로가기 [Article Type] Article
Telepsychiatry to Provide Mental Health Support to Healthcare Professionals during the COVID-19 Crisis: A Cross-Sectional Survey among 321 Healthcare Professionals in FranceArticle Published on 2021-09-272022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] approach Care clinical setting communicable contagious COVID-19 COVID-19 pandemic COVID-19 patient cross-sectional disease France healthcare healthcare professionals healthcare worker involved less management mental health multicenter Pandemics professional questionnaire receiving response Support survey Symptoms Telemedicine telepsychiatry usual care women [DOI] 10.3390/ijerph181910146 PMC 바로가기 [Article Type] Article
Sample Preparation and Diagnostic Methods for a Variety of Settings: A Comprehensive ReviewReview Published on 2021-09-182022-10-30 Journal: Molecules [Category] Coronavirus, SARS, [키워드] addition Analysis approach biochemical biosensors clinical setting Comprehensive coronavirus disease COVID-19 Diagnosis Diseases extraction High-throughput screening improvement Laboratory medical diagnosis Microfluidics Outbreaks pandemic POC point-of-care Point-of-Care (POC) point-of-care testing (POCT) preparation Prevent review Sample sample preparation separations Spread Treatment variety [DOI] 10.3390/molecules26185666 PMC 바로가기 [Article Type] Review
Rapid diagnosis of SARS-CoV-2 pneumonia on lower respiratory tract specimensResearch Article Published on 2021-09-082022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] accelerate Accuracy BAL BAS Bronchoalveolar lavage Bronchoalveolar lavage (BAL) Bronchoaspirates (BAS) can be used Characteristics clinical setting collected cycle threshold Cycle threshold value demographic diagnosis of SARS-CoV-2 diagnostic diagnostic tests distribution E gene evaluate expected feasible Germany Inc. intensive care unit intensive care units IQR Italy Lower respiratory tract LRT median molecular negative NPV PCR PCR assay Pneumonia positive PPV Predictive proportion Rapid Rapid PCR Result RT-PCR RT-PCR testing Sample size SARS-CoV-2 SARS-CoV-2 pandemic sensitivity solution South Korea specificity specimen specimens table tested threshold variables Viral load viral loads was used were expressed [DOI] 10.1186/s12879-021-06591-w PMC 바로가기 [Article Type] Research Article
Machine-learning-based COVID-19 mortality prediction model and identification of patients at low and high risk of dyingResearch Published on 2021-09-082022-11-01 Journal: Critical Care [Category] COVID-19, [키워드] Accuracy Admission Altered Analysis applied approach assigned biochemical marker Blood blood biochemical carried caused clinical feature Clinical features clinical phenotypes clinical setting Cluster cohort of patient Comorbidities Comorbidity Coronary artery coronavirus disease COVID patient COVID-19 COVID-19 mortality Critically ill CRP Dementia diabetes different clinical manifestation disease Health high accuracy high mortality rate high risk High-risk patients hospital Hospitalized hospitalized patient identify Lactate Latent machine learning management marker moderate Modification Mortality multivariate non-survivor outcome pandemic Patient patients with COVID-19 predict prediction Prediction model Predictive predictive power predictor predictors Principal component Randomly reduce Result SARS-CoV-2 status survivor Survivors the patient variable variables virus was obtained was performed were used with COVID-19 [DOI] 10.1186/s13054-021-03749-5 PMC 바로가기 [Article Type] Research
COVID-19: a fatal case of acute liver failure associated with SARS-CoV-2 infection in pre-existing liver cirrhosisCOVID-19 : 기존 간경변에서 SARS-COV-2 감염과 관련된 급성 간부전의 치명적인 경우Case Reports Published on 2021-09-032022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] accompanied ACE2 acute hepatitis acute liver failure acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 Autopsy Bile duct Case report cathepsin cathepsin L clinical setting Clinical sign Clinical signs coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 debate died differential diagnosis enzyme Evidence expression Hepatitis human tissues jaundice liver Liver cirrhosis Liver damage liver failure non-respiratory tissues Pneumonia Post-mortem respiratory SARS-CoV-2 SARS-COV-2 infection Serine severe acute respiratory syndrome Coronavirus susceptibility TMPRSS2 transmembrane serine protease transmembrane serine protease 2 Viral viral infection Viremia women [DOI] 10.1186/s12879-021-06605-7 PMC 바로가기 [Article Type] Case Reports