Molnupiravir; molecular and functional descriptors of mitochondrial safety
몰누피라비르; 미토콘드리아 안전성의 분자 및 기능 설명자
Article
Published on
Journal: Toxicology and applied pharmacology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제,
Journal: Toxicology and applied pharmacology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제,
[키워드] active form
Adult patients
Analyzer
antiviral drug
antiviral drugs
approved
arrest
cell line
Concentration
concentrations
copy number
COVID-19
Culture
cytotoxicity
DNA polymerase
dose
drug
emergency treatment
Endpoint
expression
flux
functional
Genome
HepG2
HepG2 cell
incorporation
inhibit
lack
mechanism
metabolite
Mitochondria
mitochondrial
mitochondrial DNA
Mitochondrial function
mitochondrial gene
molecular
molnupiravir
Mutation
N-hydroxycytidine
NHC
nucleoside
Patient
phenotypic
PolG
POLRMT
progression
RdRP
replicating virus
Replication
resulting
risk
RNA polymerase
significantly
specificity
the SARS-CoV-2
Toxicity
Transcription
Treatment
triphosphate
U.S. FDA
viral genome
virus
was measured
[DOI] 10.1016/j.taap.2022.116003 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.taap.2022.116003 PMC 바로가기 [Article Type] Article