Sex Differences and Predictors of In-Hospital Mortality among Patients with COVID-19: Results from the ANCOHVID Multicentre StudyArticle Published on 2021-08-262022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] active cancer addressed advanced age affected Analysis applied Autoimmune disease azithromycin treatment cardiovascular disease Clinical data cohort of patient collected conducted country COVID-19 COVID-19 pandemic CURB-65 score death difference Effect Factor hospital Hospital mortality hospitalised identify in-hospital mortality Kaplan–Meier method Lung disease median age men men and women Mortality multicentre multiple Cox regression outcome pandemic Patient predictor public health reached receiving Research Result risk factor Risk factors SARS-CoV-2 severe disease Sex Sex difference Spain stratified by sex survival was used with COVID-19 women [DOI] 10.3390/ijerph18179018 PMC 바로가기 [Article Type] Article
Association between obesity and hospital mortality in critical COVID-19: a retrospective cohort study Research Published on 2021-08-252022-10-05 Journal: International journal of obesity (2005) [Category] 임상, 치료법, 치료제, [키워드] 95% CI acute respiratory distress adjusted age ARDS association BMI body mass index caused Comorbidity conducted continuous variable COVID-19 disease Cox proportional hazard Critical critical COVID-19 patients defined entire cohort evaluate hazard ratio hospital Hospital mortality hospitalized patient ICU mechanisms morbidity and mortality Mortality multivariable obese obesity outcome Patient patients prevalent recent Respiratory disease Result retrospective cohort study SARS-CoV-2 Sex significantly survival syndrome [DOI] 10.1038/s41366-021-00938-8 [Article Type] Research
Hospital mortality in patients with rare diseases during pandemics: lessons learnt from the COVID-19 and SARS pandemicsResearch Published on 2021-08-122022-10-29 Journal: Orphanet Journal of Rare Diseases [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome adjusted admission record classification coronavirus disease Coronavirus infection COVID-19 COVID-19 pandemic database demonstrated disease General population groups healthcare Hong Kong hospital Hospital mortality ICD-10 Impact increase in Infection Local Mortality occur pandemic Pandemics Patient Population problem Public Hospital rare disease resource Result retrieved risk risk factor SARS significantly significantly higher were infected while with COVID-19 [DOI] 10.1186/s13023-021-01994-z PMC 바로가기 [Article Type] Research
Antibiotic Use and Fatal Outcomes among Critically Ill Patients with COVID-19 in Tacna, PeruArticle Published on 2021-08-092022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] Acinetobacter acute renal failure Adjusted analysis Anti-bacterial agents Antibiotics aRR Bacteria Bacterial Characteristics Complication conducted COVID-19 Critical Critically ill patient critically ill patients Cross-infection death Dexamethasone died drug resistance evaluate evolution of patients Follow-up HAI healthcare hospital Hospital mortality ICU ICU admission Ill incidence increased risk Infection infections intensive care IQR Isolation median Mortality occurred organism pandemic pathogen Patient patients evaluated patients with COVID-19 Peru proportion Pseudomonas aeruginosa required retrospective cohort study SARS-CoV-2 significantly with COVID-19 [DOI] 10.3390/antibiotics10080959 PMC 바로가기 [Article Type] Article
An observational cohort study to assess N-acetylglucosamine for COVID-19 treatment in the inpatient settingResearch article Published on 2021-08-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 임상, 치료법, [키워드] Administered administration Admission affected Analysis anti-inflammatory activity Clinical outcome confidence interval control group Coronavirus disease 2019 COVID-19 effective Effects enrolled evaluated Follow-up hospital Hospital mortality Hospitalization ICU ICU admission ICU admission rates immune response IMPROVE independent intensive care intensive care units intubation Length of stay material median age modulate Mortality multivariate Multivariate analysis N-Aceytlglucosamine Observational cohort study Odds ratio Patient Primary outcome reduced Registration Result retrospective secondary outcome significantly lower single-center standard care supplemental oxygen Treatment treatment group Trial Univariate analysis with COVID-19 [DOI] 10.1016/j.amsu.2021.102574 [Article Type] Research article
Von Willebrand factor collagen-binding capacity predicts in-hospital mortality in COVID-19 patients: insight from VWF/ADAMTS13 ratio imbalance폰 빌레브란트 인자 콜라겐 결합 능력은 COVID-19 환자의 병원 내 사망률을 예측합니다: VWF/ADAMTS13 비율 불균형으로부터의 통찰력Article Published on 2021-08-012022-09-11 Journal: Angiogenesis [Category] SARS, 바이오마커, [키워드] 48 hour 48 hours 95% CI ADAMTS13 adjusted Admission Analysis AUC balance best Biomarker BMI C-reactive protein collagen Collagen-binding COVID-19 COVID-19 severity Critical cut-off D-dimer levels described enrolled hallmark hazard Hospital mortality hospitalized COVID-19 patient in-hospital mortality IQR Kaplan-Meier estimator median Microthrombosis molecular weight Mortality Multimers Patient Plasma level Plasma levels predict Predictive ROC Curve shown significantly subsequent Trigger von Willebrand factor vWF was increased were measured [DOI] 10.1007/s10456-021-09789-3 PMC 바로가기 [Article Type] Article
Impact on polytrauma patient prehospital care during the first wave of the COVID-19 pandemic: a cross-sectional studyOriginal Article Published on 2021-07-302022-11-01 Journal: European Journal of Trauma and Emergency Surgery [Category] COVID-19, MERS, SARS, [키워드] Activation affected Analysis assigned burns Care caused Characteristics clinical variable code conducted COVID-19 COVID-19 pandemic cross-sectional decrease determine Emergency epidemiological First wave Hospital mortality Impact increase in Injury Logistic regression Nonparametric tests objective pandemic pathology Patient patients Polytrauma prehospital presenting priority remained representing respond Result SARS-CoV-2 severity study period Support System Timely life-saving interventions treated [DOI] 10.1007/s00068-021-01748-3 PMC 바로가기 [Article Type] Original Article
Early but not late convalescent plasma is associated with better survival in moderate-to-severe COVID-19초기의 후기 회복기 혈장은 중등도에서 세상에서 더 나은 생존과 관련이 있습니다.Research Article Published on 2021-07-282022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] addressed administration administration of CCP Analysis CCP CCP administration Cohort Complete conducted convalescent plasma coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 convalescent plasma COVID-19 infection days alive discharge disease Endpoint Follow-up had more hospital hospital discharge Hospital mortality Hospital stay IMPROVE in-hospital mortality Inpatient investigated likelihood Limited mechanical ventilation median moderate-to-severe COVID-19 Mortality on mechanical ventilation outcome Patient plasma primary endpoint primary endpoints Propensity score question receive recipient recipients Research question Result secondary Secondary endpoints Study design survival therapeutic therapeutic option transfused trials ventilator WHO [DOI] 10.1371/journal.pone.0254453 PMC 바로가기 [Article Type] Research Article
A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trialSARS Cov-2 감염으로 입원한 환자에서 아스피린, 아토르바스타틴, 니코란딜을 사용한 삼중 요법의 효능과 안전성을 평가하기 위한 무작위 공개 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-07-152022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 ACHE Acute coronary syndrome Acute kidney injury acute renal failure adequate hydration adjuvant therapy Admission allergy ALT/AST Altered mental status Anti-inflammatory anticoagulation antipyretics Antithrombotic approved ARDS Aspirin AST/ALT atorvastatin bleeding Blinding block randomization Breastfeeding brown urine change characterized clinical clinical feature Clinical features Coagulopathy college Combination comorbid condition comorbid conditions comparator conducted control group coronary syndrome Corticosteroid Corticosteroids cough COVID-19 CPK creatine creatine kinase creatinine CRP current therapy Dexamethasone dissemination dose drug dysfunction Dyspnoea dysregulation effective Efficacy and safety element Endothelial dysfunction enrolled ethical committee evaluate excluded ferritin Fever followed by greater heparin hepatotoxicity Hospital admission hospital discharge Hospital mortality Hospital stay hospitalised patient Hospitalised patients hyperbilirubinemia hypoxia ICMR IEC immune dysregulation immunomodulatory impaired consciousness in-hospital mortality India Inflammation Inflammatory marker inflammatory markers Intervention intervention group intolerance intravenous Intravenous remdesivir invasive limit liver low molecular weight low molecular weight heparin management marker mechanical ventilation medication medications moderate muscle ache myalgia Myoglobin Myopathy myositis national guidelines Nicorandil Non-invasive number objective once daily Open-label open-label trial outcome oxygen Oxygen requirement oxygen support participant pathophysiologic pathophysiology Patient Platelet Platelet count Pneumonia positive Pregnancy Primary outcome progression protocol raised Rajendra Prasad Randomised control trial randomization randomize Randomized Randomized controlled trial randomly divided receive recruitment reducing mortality Registered registry Remdesivir renal failure reported respiratory rate rhabdomyolysis room air RT-PCR safety endpoint safety endpoints Sample size SARS-CoV-2 infected patient SARS-COV-2 infection Schematic screened Secondary outcomes Sepsis serum serum markers severe disease Shock significant interaction SpO2 Standard Standard of care starting dose statin statins Study design Study protocol substrates supplementary material Symptom Symptomatic treatment Tablet therapeutic therapeutic agent therapy thrombocytopenia Treatment Trial Trial registration two-arm parallel ULN Urine weakness website [DOI] 10.1186/s13063-021-05361-y PMC 바로가기 [Article Type] Letter
Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021*2019년 영국 코로나바이러스 질환 중환자의 28일 사망률 추세: 전국 코호트 연구, 2020년 3월~2021년 1월*Multicenter Study Published on 2021-07-132022-09-11 Journal: Critical Care Medicine [Category] MERS, SARS, 변종, [키워드] 28-day mortality 95% CI adjusted Admission age Characteristics Comorbidities content coronavirus disease Coronavirus disease 2019 Coronavirus infection Cox proportional hazard models Critical care Deprivation described Deterioration determine Digital Digital Content dominant England English Ethnicity First wave geographic location group high dependency unit hospital Hospital mortality ICU increased mortality independent independent of Mortality not applicable outcome Patient Primary outcome public health surveillance quality of healthcare recorded reflect required Research retrospective cohort study reversed second wave Sex social deprivation subgroup System text trend trough levels United Kingdom variant were used [DOI] 10.1097/CCM.0000000000005184 PMC 바로가기 [Article Type] Multicenter Study