NETs

[키워드] Abstract accumulation acute respiratory distress Adverse reaction AF, Alexa Fluor airway airways analyses Analysis approved ARDS, acute respiratory distress syndrome blood plasma CF, cystic fibrosis change clinically components contribute coronavirus disease COT, conventional oxygen therapy COVID-19 COVID-19 disease COVID-19, Coronavirus disease 2019 DAPI, 4,6 diamidino-2-phenylindole DIA-MS, data-independent acquisition MS DNA DNase ECMO, extracorporeal membrane oxygen therapy extracellular DNA FDR, false discovery rate FiO₂, fraction of inspired oxygen FIVE GGO, glass ground opacity hallmark hemorrhage HFNO, high-flow nasal oxygenation high-flow oxygen therapy hindrance Hypoxemia immunofluorescence implication IMPROVE infections Inflammation iRT, indexed retention time peptides Lung function mass spectrometry Microscopy NE, neutrophil elastase NET NET, neutrophil extracellular trap NETs Neutrophil extracellular trap oxygen saturation Oxygenation PADI-4, peptidyl arginine deiminase IV Patient patients plasma Pneumonia Profiling proteome pulmonary inflammation Quantitative recombinant reduce reduced reducing reduction Respiratory failure rhDNase, recombinant human DNase I Roche SARS-CoV2, severe acute respiratory syndrome coronavirus 2 severe COVID-19 patient severe COVID-19 patients Severe patient severely ill patient shown SpO₂, the oxygen saturation as measured by pulse oximetry sputum statistically significant Symptom syndrome systemic inflammatory targeting the disease therapeutic therapy treated Treatment with COVID-19
[DOI] 10.1016/j.mcpro.2021.100113 PMC 바로가기 [Article Type] Research