Antimicrobial susceptibility patterns of respiratory Gram-negative bacterial isolates from COVID-19 patients in SwitzerlandObservational Study Published on 2021-09-072022-10-04 Journal: Annals of Clinical Microbiology and Antimicrobials [Category] SARS, 임상, [키워드] Aminoglycoside Analysis analyzed antibiotic Antibiotic therapy antimicrobial resistance antimicrobial susceptibility Apramycin assays Bacterial Bacterial infection bacterial superinfection collected contributed Coverage COVID-19 COVID-19 patient COVID-19 patients diffusion drug effective frameshift groups ICU patient isolate Lower respiratory tract lung morbidity Mutation Patient phenotypic Pneumonia profile provided Pseudomonas aeruginosa Result Specy Strains superinfection supplementary material susceptibility susceptible Switzerland transcriptional regulator Treatment Ventilated Ventilator-associated bacterial pneumonia was performed whole-genome sequencing with COVID-19 [DOI] 10.1186/s12941-021-00468-1 PMC 바로가기 [Article Type] Observational Study
Acute SARS-CoV-2 infection is associated with an increased abundance of bacterial pathogens, including Pseudomonas aeruginosa in the nose급성 SARS-CoV-2 감염은 코의 녹농균(Pseudomonas aeruginosa)을 비롯한 세균성 병원체의 풍부함 증가와 관련이 있습니다Article Published on 2021-08-312022-09-11 Journal: Cell Reports [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral Bacterial infections bacterial pathogen Bacterial pathogens caused Coinfection conducted contribute coronavirus coronavirus disease Coronavirus disease 2019 CoV COVID-19 Diagnosis epithelia healthcare worker host response Host transcriptional response incidence Infection Inflammation Inflammatory response innate immune response Microbiome nasal Nasal cavity nasal microbiome neuronal observé Outpatient Pathogenesis Pathogens patients Pseudomona Pseudomonas aeruginosa RNA-Seq robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-positive patient SARS-CoV-2-positive patients Secondary bacterial infections severe acute respiratory syndrome Coronavirus severely ill patients These data unique viral RNA load [DOI] 10.1016/j.celrep.2021.109637 PMC 바로가기 [Article Type] Article
Contamination of Hospital Surfaces with Bacterial Pathogens under the Current COVID-19 OutbreakArticle Published on 2021-08-272022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] 16S rRNA Achromobacter affected antimicrobial drugs approach bacterial pathogen caused circulating condition controlling COVID-19 COVID-19 disease COVID-19 patients Critical current disease DNA epidemiological ESKAPE Evolution of SARS-CoV-2 form Health hospital Hospital infection hospitals Immunity indicate Infection Infectious disease Klebsiella pneumoniae lack Measures Microbiome microorganism microorganisms Neutralizing antibodies NGS sequencing nosocomial pathogenic pathogenic bacteria Pathogens patients with moderate PCR Pseudomonas aeruginosa reservoir risk SARS-CoV-2 pandemic severity significantly Staphylococcus aureus surface surface contamination the disease Transmission Treatment vaccination rate viability [DOI] 10.3390/ijerph18179042 PMC 바로가기 [Article Type] Article
Application of validated severity scores for pneumonia caused by SARS-CoV-2Observational Study Published on 2021-08-132022-10-05 Journal: Medicina clínica [Category] 임상, [키워드] Accuracy Admission admitted to ICU application Area Bacterial bacterial co-infection caused Co-infection coronavirus COVID-19 COVID-GRAM CURB-65 enrolled Escalas pronósticas excluded Hospitalized ICU admission identify Immunocompromised patients Invasive mechanical ventilation Klebsiella pneumoniae Mortality Neumonía overall mortality Patient patients with pneumonia Penumonia Pneumonia predict Predictive prognostic Pseudomonas aeruginosa PSI required respiratory tract respiratory tract infection ROC Curve SARS-CoV-2 sensitivity Severity Score Severity scores. specificity strain was performed [DOI] 10.1016/j.medcli.2021.01.002 PMC 바로가기 [Article Type] Observational Study
Dynamics of SARS-CoV2 Infection and Multi-Drug Resistant Bacteria Superinfection in Patients With Assisted Mechanical VentilationSARS-COV2 감염의 역학 및 기계적 환기가 보조 된 환자에서 SARS-COV2 감염 및 다 약성 내성 박테리아 초부 감염Cellular and Infection Microbiology Published on 2021-08-122022-08-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] 2019-nCoV assay antimicrobial resistance Bacteria Bacterial bacterial and fungal infections bacterial superinfection bronchial aspirate samples carbapenem carbapenems carried CFU characterisation colonisation colony forming units COVID-19 COVID-19 disease COVID-19 patients Culture Deletion demonstrated detection dithiothreitol Dynamics Evolution fungal Fungal infection fungi growth Health hospitalisation ICU incidence intensive care intensive care unit isolate Klebsiella pneumoniae Mechanical mechanically ventilated patient mechanically ventilated patients molecular analysis Mutation objective outcome pathogen Patient patients pneumoniae Prospective Study Pseudomonas aeruginosa Resistant Result room temperature SARS-CoV-2 SARS-CoV-2-infected patient SARS-CoV2 severe COVID-19 disease severe SARS specimen Strains superinfection temperature These data treated was performed [DOI] 10.3389/fcimb.2021.683409 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Antibiotic Use and Fatal Outcomes among Critically Ill Patients with COVID-19 in Tacna, PeruArticle Published on 2021-08-092022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] Acinetobacter acute renal failure Adjusted analysis Anti-bacterial agents Antibiotics aRR Bacteria Bacterial Characteristics Complication conducted COVID-19 Critical Critically ill patient critically ill patients Cross-infection death Dexamethasone died drug resistance evaluate evolution of patients Follow-up HAI healthcare hospital Hospital mortality ICU ICU admission Ill incidence increased risk Infection infections intensive care IQR Isolation median Mortality occurred organism pandemic pathogen Patient patients evaluated patients with COVID-19 Peru proportion Pseudomonas aeruginosa required retrospective cohort study SARS-CoV-2 significantly with COVID-19 [DOI] 10.3390/antibiotics10080959 PMC 바로가기 [Article Type] Article
Emergence of Resistance to Novel Cephalosporin-β-Lactamase Inhibitor Combinations through the Modification of the Pseudomonas aeruginosa MexCD-OprJ Efflux Pump녹농균 MexCD-OprJ 유출 펌프의 변형을 통한 새로운 Cephalosporin-β-Lactamase 억제제 조합에 대한 내성의 출현Article Published on 2021-07-162022-09-11 Journal: Antimicrobial Agents and Chemotherapy [Category] SARS, 변종, [키워드] avibactam Azithromycin carbapenem caused ceftolozane ceftolozane-tazobactam cephalosporin Combination construction COVID-19 infection efflux efflux pumps. emergence evidenced inhibitor meropenem MexCD-OprJ Missense mutation Modification mutant Mutation nonsense mutation novel Patient periplasmic Pseudomona Pseudomonas aeruginosa pump resistance Sequencing specificity strain tazobactam Treatment Ventilator-associated pneumonia whole-genome sequencing wild-type [DOI] 10.1128/AAC.00089-21 PMC 바로가기 [Article Type] Article
Quantitative mapping of mRNA 3’ ends in Pseudomonas aeruginosa reveals a pervasive role for premature 3’ end formation in response to azithromycinPseudomonas aeruginosa에서 mRNA 3 '끝의 정량적 매핑은 아지트로 마이신에 대한 반응으로 조기 3'말단 형성에 대한 광범위한 역할을 보여줍니다.Research Article Published on 2021-07-122022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 3’ end accompanied accumulation Alter antibiotic Antibiotics approach Azithromycin azithromycin treatment cause change changes in chronic infection chronic infections clinical outcomes control gene Culture cystic fibrosis downregulated downregulated gene expression fibrosis Gene Expression Gene regulation Genes growth GTPase Hospital-acquired infection hospital-acquired infections hospitalized patient hospitalized patients immunocompromised individuals impair improve clinical outcome incidence Infection involved Macrolide mechanism molecular mechanism molecular mechanisms MOST mRNA nucleases nucleotide P . aeruginosa Patient persistence planktonic Premature promote provide Pseudomonas aeruginosa quorum reduced Regulation regulatory element respond resulting reveal RNA robust Stress stress response subject Support therapeutic intervention thought transcript Transcription transcriptional transcriptional response treated Treatment turn upregulated genes upregulating virulence [DOI] 10.1371/journal.pgen.1009634 PMC 바로가기 [Article Type] Research Article
Two Consecutive Runs of Veno-Venous Extracorporeal Membrane Oxygenation in a Peripartum Patient with COVID-19 Acute Respiratory Distress SyndromeCase Report Published on 2021-07-092022-10-31 Journal: Case Reports in Critical Care [Category] COVID-19, [키워드] acute respiratory distress anticoagulation ARDS characterized complications COVID-19 Critically ill patient decannulated discharged home Electrical impedance tomography Extracorporeal extracorporeal membrane oxygenation Follow-up general condition initiated inspired oxygen fraction lung mechanical ventilation oxygen Oxygen therapy Patient prone positioning Pseudomonas aeruginosa reduction required respiratory Respiratory failure Respiratory system severe hypoxemia static compliance Support syndrome treat V-V ECMO ventilator Ventilator-associated pneumonia with COVID-19 [DOI] 10.1155/2021/2032197 PMC 바로가기 [Article Type] Case Report
Immunomodulatory therapy, risk factors and outcomes of hospital-acquired bloodstream infection in patients with severe COVID-19 pneumonia: a Spanish case–control matched multicentre study (BACTCOVID)Original Article Published on 2021-07-072022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, MERS, [키워드] 1:1 Abstract accounted acute respiratory distress Admission age Analysis Bacteraemia bloodstream BSI caused characteristics of patient Cohort combinations Control Corticosteroids COVID-19 database Enterococcus hazard ratio Hospital-acquired infection Hospitalized hospitalized patient identify Image immunomodulatory drug immunomodulatory therapy in-hospital mortality increased risk Infection IQR median time mortality risk multicentre objective outcome Patient patients patients with COVID-19 performed polymicrobial infection prospective cohort Pseudomonas aeruginosa Result risk risk factor SARS-CoV-2 pneumonia severe COVID-19 Severe COVID-19 pneumonia severity Sex Spanish syndrome therapy time factor Tocilizumab was performed with COVID-19 [DOI] 10.1016/j.cmi.2021.06.041 PMC 바로가기 [Article Type] Original Article